[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100560706":3},{"organization":4,"armGroups":7,"interventions":26,"overallOfficials":32,"centralContacts":36,"locations":41,"responsibleParty":76,"collaborators":10,"id":79,"slug":80,"hasResults":81,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":85,"eligibilityCriteria":86,"healthyVolunteers":87,"sex":88,"minAge":89,"maxAge":10,"enrollmentInfo":90,"targetDuration":10,"studyType":93,"phases":10,"briefSummary":94,"conditions":95,"keywords":10,"overallStatus":44,"whyStopped":10,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":106,"locationsCount":107},{"fullName":5,"class":6},"Linkoeping University","OTHER_GOV",[8,14,18,22],{"label":9,"type":10,"description":11,"interventionNames":12},"Healthy Individuals",null,"Patients with a negative IGRA (Quantiferon) who are apparently healthy.",[13],"Other: No intervention.",{"label":15,"type":10,"description":16,"interventionNames":17},"Close contacts to patients with active TB","Close contacts to patients with active, smear positive pulmonary TB.",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Patients with (latent) tuberculosis infection","Patients without active TB who have a positive IGRA (Quantiferon Plus) result.",[13],{"label":23,"type":10,"description":24,"interventionNames":25},"Patients with active TB","Culture or PCR-verified active TB who are initiated on treatment.",[13],[27],{"type":28,"name":29,"description":30,"armGroupLabels":31,"otherNames":10},"OTHER","No intervention.","Blood sampling for analysis of mycobacterial growth inhibition assay (MGIA) analysis.",[15,9,19,23],[33],{"name":34,"affiliation":5,"role":35},"Thomas Schoen, Professor","PRINCIPAL_INVESTIGATOR",[37],{"name":34,"role":38,"phone":39,"phoneExt":10,"email":40},"CONTACT","+48013580000","tschon@hotmail.com",[42,59],{"facility":43,"status":44,"city":45,"state":10,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"Kalmar County Hospital","RECRUITING","Kalmar","391 85","Sweden","SE",{"type":50,"coordinates":51},"Point",[52,53],16.36163,56.66157,{"lat":53,"lon":52},[56],{"name":57,"role":38,"phone":58,"phoneExt":10,"email":40},"Thomas Schön, Professor","+46103850000",{"facility":60,"status":44,"city":61,"state":10,"zip":62,"country":47,"countryCode":48,"cosmosGeoPoint":63,"geoPoint":67,"contacts":68},"Dept of Infectious Diseases","Linköping","581 85",{"type":50,"coordinates":64},[65,66],15.62157,58.41086,{"lat":66,"lon":65},[69,71,74],{"name":57,"role":38,"phone":70,"phoneExt":10,"email":40},"+461010000000",{"name":72,"role":73,"phone":10,"phoneExt":10,"email":10},"Jakob Paues, MD PhD","SUB_INVESTIGATOR",{"name":75,"role":73,"phone":10,"phoneExt":10,"email":10},"Katarina Niward, MD PhD",{"type":35,"investigatorFullName":77,"investigatorTitle":78,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Thomas Schon","Professor","100560706","the-role-of-a-mycobacterium-growth-inhibition-assay-to-quantify-host-immune-control-of-m-tuberculosis-100560706",false,"NCT06580639","The Role of a Mycobacterium Growth Inhibition Assay to Quantify Host Immune Control of M. Tuberculosis","The Role of a Mycobacterium Growth Inhibition Assay to Quantify Host Immune Control of M. Tuberculosis From Healthy Blood Donors and Patients With Latent or Active Tuberculosis.","MGIA","Inclusion Criteria: Healthy blood donors or subjects who will get vaccinated.\n\nExclusion Criteria:Known HIV infection, not Swedish citizen, chronic liver och kidney disease,immunosuppression from treatment or disease.",true,"ALL","18 Years",{"count":91,"type":92},280,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to learn about how the blood leucocytes from patients with and without exposure or disease from tuberculosis (TB) are able to kill live mycobacteria (M. tuberculosis). The main question it aims to answer is:\n\nIs intracellular growth suppression of M. tuberculosis in peripheral blood mononuclear cells variable among healthy blood donors and higher than in patients with latent TB compared to active TB?",[96,97],"Tuberculosis","Immunologic Activity Alteration","2024-08-28",{"date":100,"type":101},"2024-08-30","ACTUAL",{"date":103,"type":101},"2020-08-01",{"date":105,"type":92},"2025-12-01",{"name":5,"class":6},2]