[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100583365":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":11,"centralContacts":29,"locations":11,"responsibleParty":35,"collaborators":11,"id":37,"slug":38,"hasResults":39,"nctId":40,"briefTitle":41,"officialTitle":42,"acronym":11,"eligibilityCriteria":43,"healthyVolunteers":44,"sex":45,"minAge":46,"maxAge":47,"enrollmentInfo":48,"targetDuration":11,"studyType":51,"phases":52,"briefSummary":54,"conditions":55,"keywords":11,"overallStatus":57,"whyStopped":11,"lastUpdateSubmitDate":58,"lastUpdatePostDateStruct":59,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":11},{"fullName":5,"class":6},"Wecare Probiotics Co., Ltd.","INDUSTRY",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Placebo group","PLACEBO_COMPARATOR",null,[13],"Dietary Supplement: Placebo",{"label":15,"type":16,"description":11,"interventionNames":17},"Probiotic group","EXPERIMENTAL",[18],"Dietary Supplement: probiotic LH76",[20,25],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":11},"DIETARY_SUPPLEMENT","probiotic LH76","Intervention with LH76 (30 billion CFU\u002F day, 3g) was administered daily for 8 weeks. Store in a cool, dry place.",[15],{"type":21,"name":26,"description":27,"armGroupLabels":28,"otherNames":11},"Placebo","Every day to give 3 g maltodextrin intervention for 8 weeks. Store in a cool and dry place.",[9],[30],{"name":31,"role":32,"phone":33,"phoneExt":11,"email":34},"Fei Xu, Dr.","CONTACT","13671979116","xu.fei@haut.edu.cn",{"type":36,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100583365","the-role-of-probiotic-lh76-in-human-gut-health-100583365",false,"NCT06875375","The Role of Probiotic LH76 in Human Gut Health","A Clinical Study on the Safety and Efficacy of Probiotic LH76 in Modulating Gut Microbiota and Enhancing Intestinal Health in Healthy Adults","Inclusion Criteria:\n\n1. Willing to undergo 3 follow-up visits during the intervention period Be willing to provide blood, urine and stool samples 2 times during the intervention period\n2. Willing to self-administer probiotic or placebo once a day during the intervention period\n3. Good eyesight, can read and write, can wear glasses\n4. Have good hearing and be able to hear and understand all instructions during the intervention\n\nExclusion Criteria:\n\n1. Digestive diseases, mainly gastrointestinal diseases (celiac disease, ulcerative colitis, Crohn's disease)\n2. Have a serious neurological condition (epilepsy, stroke, severe head trauma, meningitis in the last 10 years, brain surgery, brain tumor, prolonged coma - not including general anaesthesia)\n3. Have received\u002Fare receiving treatment for the following mental disorders: alcohol\u002Fdrug\u002Fsubstance abuse dependence, schizophrenia, psychosis, bipolar disorder\n4. Take medication for depression or low mood Internal organ failure (heart, liver or kidney failure, etc.)\n5. Have received radiation or chemotherapy in the past\n6. Have undergone a general anesthesia procedure\u002Fprocedure within the past three years, or plan to undergo a general anesthesia procedure\u002Fprocedure within the next 3 months during this trial period\n7. Have had hepatitis (hepatitis B, hepatitis C), HIV or syphilis in the past Open Contacts\u002FLocations",true,"ALL","18 Years","45 Years",{"count":49,"type":50},50,"ESTIMATED","INTERVENTIONAL",[53],"NA","This study aims to evaluate the safety and efficacy of the probiotic LH76 as a dietary supplement in healthy adults. The research will assess its effects on gut microbiota composition, intestinal health, and immune function compared to a placebo. Key outcomes include changes in microbial diversity, intestinal barrier integrity, and immune response markers over the intervention period. The findings will contribute to understanding the potential health benefits of LH76 and its role in supporting gut and immune health.",[56],"Gut Microbiota Modulation","NOT_YET_RECRUITING","2025-03-13",{"date":60,"type":61},"2025-03-18","ACTUAL",{"date":63,"type":50},"2025-05-11",{"date":65,"type":50},"2025-10-26",{"name":5,"class":6}]