[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100379910":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":24,"centralContacts":28,"locations":36,"responsibleParty":52,"collaborators":55,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":64,"eligibilityCriteria":65,"healthyVolunteers":66,"sex":67,"minAge":68,"maxAge":69,"enrollmentInfo":70,"targetDuration":23,"studyType":73,"phases":74,"briefSummary":76,"conditions":77,"keywords":80,"overallStatus":38,"whyStopped":23,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"Hasselt University","OTHER",[8,13],{"label":9,"type":6,"description":10,"interventionNames":11},"Multiparous, pregnant women","Multiparous women are followed over time and measurements are performed during the first and third pregnancy trimester, and six weeks and six months postpartum.",[12],"Behavioral: Assessment of postural control, body perception, psychosocial factors and inflammation",{"label":14,"type":6,"description":15,"interventionNames":16},"Nulliparous women","Nulliparous women are measured at one timepoint and their data are compared to the data of the multiparous women. Nulliparous women who take part in the reliability study are measured twice.",[12],[18],{"type":19,"name":20,"description":21,"armGroupLabels":22,"otherNames":23},"BEHAVIORAL","Assessment of postural control, body perception, psychosocial factors and inflammation","Behavioral assessment of postural control, lumbar proprioceptive use during postural control, back-specific body perception, psychosocial factors (incl. perceived harmfulness of daily activities, pain-related fear of movement, fear-avoidance beliefs, (pregnancy-related) depression, anxiety and stress, optimism\u002Fpessimism, pain coping and coping with stressful life events) and inflammatory mediators",[9,14],null,[25],{"name":26,"affiliation":5,"role":27},"Lotte Janssens, PhD, PT","PRINCIPAL_INVESTIGATOR",[29,34],{"name":30,"role":31,"phone":32,"phoneExt":23,"email":33},"Nina Goossens, PhD, PT","CONTACT","+3211292174","nina.goossens@uhasselt.be",{"name":26,"role":31,"phone":32,"phoneExt":23,"email":35},"lotte.janssens@uhasselt.be",[37],{"facility":5,"status":38,"city":39,"state":23,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"RECRUITING","Hasselt","3590","Belgium","BE",{"type":44,"coordinates":45},"Point",[46,47],5.33781,50.93106,{"lat":47,"lon":46},[50],{"name":51,"role":31,"phone":23,"phoneExt":23,"email":23},"Nina Goossens, PhD",{"type":27,"investigatorFullName":53,"investigatorTitle":54,"investigatorAffiliation":5,"oldNameTitle":23,"oldOrganization":23},"Lotte Janssens","Professor",[56],{"name":57,"class":6},"Ziekenhuis Oost-Limburg","100379910","the-role-of-proprioceptive-deficits-psychosocial-factors-and-inflammation-in-pregnancy-related-pelvic-girdle-pain-100379910",false,"NCT04226716","The Role of Proprioceptive Deficits, Psychosocial Factors and Inflammation in Pregnancy-related Pelvic Girdle Pain","The Role of Lumbar Proprioceptive Deficits, Psychosocial Factors and Inflammation in Pregnancy-related Pelvic Girdle Pain: a Follow-up Study in Multiparous Pregnant Women","PROFit","Inclusion Criteria Multiparous Women:\n\n* Singleton pregnancy\n* Pregnant of second child or more than second child\n* No current PPGP or did not have PPGP during current pregnancy\n* Willing to provide written informed consent\n\nExclusion Criteria Multiparous Women:\n\n* Pregnant for more than 16 weeks\n* Having current PPGP or having had PPGP during the current pregnancy\n* History of surgery\u002Fmajor trauma to spine or pelvis\n* Surgery\u002Fphysical trauma to the lower limbs more than two years ago and currently still experiencing symptoms such as pain, instability, or stiffness\n* Surgery\u002Fphysical trauma to the lower limbs less than two years ago\n* Specific balance or vestibular disorders\n* A medical diagnosis of a rheumatic condition or being under treatment for such a condition by a rheumatologist\n* Neurological abnormalities (e.g., peripheral neuropathy)\n* Uncorrected visual problems\n* Acute ankle problems\n* Being on absolute or relative bed rest due to pregnancy-related complications\n* Having (had) a formal diagnosis of a psychiatric disorder\n* Non-Dutch speaking\n\nInclusion Criteria Nulliparous Women:\n\n* Age- and BMI- matched to pregnant participants\n* Nulliparous\n* Willing to provide written informed consent\n\nExclusion Criteria Nulliparous Women:\n\n* Having low back or pelvic girdle pain at the time of inclusion or in the six months leading up to inclusion\n* History of chronic low back or pelvic girdle pain\n* History of surgery\u002Fmajor trauma to spine, pelvis and\u002For lower limbs,\n* Specific balance or vestibular disorders\n* Spinal deformities\n* Rheumatic disease\n* Neurological abnormalities\n* Acute ankle problems\n* (A history of) psychiatric disorders\n* Uncorrected visual problems\n* Non-Dutch speaking",true,"FEMALE","18 Years","40 Years",{"count":71,"type":72},192,"ESTIMATED","INTERVENTIONAL",[75],"NA","A large proportion of pregnant women develop pregnancy-related low back and\u002For pelvic girdle pain (PPGP), which often does not recover spontaneously postpartum. As a result, 10% of women with PPGP are thus crucial. However, the underlying mechanisms of PPGP are still poorly understood. The main objective of this study is to investigate whether lumbar proprioceptive deficits, a disturbed body perception at the lumbar spine, psychosocial factors (incl. pain-related fear of movement, depression, anxiety and stress) and increased serum concentrations of specific inflammatory mediators are associated with (1) a reduced postural control and (2) the development and\u002For persistence of PPGP in multiparous women during the first and third trimester of pregnancy, and six weeks and six months postpartum.",[78,79],"Pelvic Girdle Pain","Low Back Pain",[81,82,83,84],"Postural control","Body perception","Psychosocial factors","Inflammation","2026-02-27",{"date":87,"type":88},"2026-03-03","ACTUAL",{"date":90,"type":88},"2020-06-01",{"date":92,"type":72},"2028-09-30",{"name":5,"class":6},1]