[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100592576":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":13,"centralContacts":18,"locations":27,"responsibleParty":45,"collaborators":7,"id":49,"slug":50,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":7,"eligibilityCriteria":55,"healthyVolunteers":51,"sex":56,"minAge":57,"maxAge":7,"enrollmentInfo":58,"targetDuration":61,"studyType":62,"phases":7,"briefSummary":63,"conditions":64,"keywords":67,"overallStatus":29,"whyStopped":7,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":81},{"fullName":5,"class":6},"Gulhane Training and Research Hospital","OTHER_GOV",null,[9],{"type":10,"name":11,"description":12,"armGroupLabels":7,"otherNames":7},"DIAGNOSTIC_TEST","renal resistive index with Doppler ultrasound","Renal resistive index uses doppler ultrasonography which assesses blood flow velocity in the renal arteries. The Renal Resistive Index (RI) is calculated by substracting diastolic velocity from systolic velocity then dividing result by systolic velocity\n\nWhere:\n\nSystolic velocity is the peak velocity of the blood flow during the systolic phase of the cardiac cycle.\n\nDiastolic velocity is the velocity of blood flow during the diastolic phase.",[14],{"name":15,"affiliation":16,"role":17},"Gürhan T associate professor doctor","Gulhane Education and Research Hospital Ankara Türkiye","STUDY_DIRECTOR",[19,24],{"name":20,"role":21,"phone":22,"phoneExt":7,"email":23},"Mete E specialist","CONTACT","+905066321175","meteerdemir@hotmail.com",{"name":15,"role":21,"phone":25,"phoneExt":7,"email":26},"+905057202781","drgurhantaskin@gmail.com",[28],{"facility":16,"status":29,"city":30,"state":31,"zip":32,"country":33,"countryCode":7,"cosmosGeoPoint":34,"geoPoint":39,"contacts":40},"RECRUITING","Ankara","Türkiye","06010","Turkey (Türkiye)",{"type":35,"coordinates":36},"Point",[37,38],32.85427,39.91987,{"lat":38,"lon":37},[41,42,43],{"name":20,"role":21,"phone":22,"phoneExt":7,"email":23},{"name":15,"role":21,"phone":25,"phoneExt":7,"email":26},{"name":20,"role":44,"phone":7,"phoneExt":7,"email":7},"SUB_INVESTIGATOR",{"type":46,"investigatorFullName":47,"investigatorTitle":48,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"PRINCIPAL_INVESTIGATOR","Mete Erdemir","principal investigator","100592576","the-role-of-renal-resistive-index-ri-in-predicting-acute-kidney-injury-progression-in-intensive-care-clinic-100592576",false,"NCT06995222","The Role of Renal Resistive Index (RI) in Predicting Acute Kidney Injury Progression in Intensive Care Clinic","The Role of Renal Resistive Index (RI) in Predicting Acute Kidney Injury Progression and Need for Renal Replacement Therapy in Patients Followed in the Intensive Care Clinic","Inclusion Criteria:\n\n1. Being over 18 years of age\n2. Having KDIGO stage 1 or stage 2 acute kidney injury within the first 24 hours of admission\n\nExclusion Criteria:\n\n* 1\\. Patients who did not provide a consent form for participation in the study 2. Patients under 18 years of age 3. Pregnant women 4. Patients with postrenal acute kidney injury 5. Patients 24 hours after the diagnosis of acute kidney injury 6. Patients with acute kidney injury in the recovery period 7. Patients who were evaluated as KDIGO ABH stage 3 during hospitalization 8. Patients with a known history of renal artery stenosis 9. Patients with a diagnosis of cardiac arrhythmia 10. Patients with a diagnosis of chronic kidney disease and a glomerular filtration rate below 30 ml\u002Fmin\u002F1.73m2 11. Patients with intra-abdominal pressure above 20 mmHg 12. Patients with a hospitalization period of less than 24 hours","ALL","18 Years",{"count":59,"type":60},120,"ESTIMATED","28 Days","OBSERVATIONAL","Acute kidney injury(AKI) is defined in the KDIGO guidelines as a ≥0.3 mg\u002FdL (≥26.5 micromol\u002FL) increase in serum creatinine in the previous 48 hours or a ≥1.5-fold increase in serum creatinine from baseline, known or presumed to have occurred in the previous seven days, or a urine volume \\\u003C0.5 mL\u002Fkg\u002Fhour for six hours.\n\nGiven the high morbidity and mortality associated with AKI, many investigators are studying several novel biomarkers to detect AKI progression earlier, identify etiologies and predict outcomes. However, the utilisation of these novel biomarkers may be constrained by reimbursement considerations.\n\nThe renal resistive index (RRI) is a well-established metric for evaluating renal perfusion; however, its application in the context of AKI has been a subject of recent debate. While RRI has been utilised to demonstrate perfusion in acute and chronic renal diseases, particularly in conjunction with ultrasonography, its efficacy remains a subject of scientific discourse. In addition, Boddi reported that RRI is a strong indicator of mortality and a diagnostic marker, especially in patients with persistent AKI.\n\nThe present study aims to evaluate the appropriateness of using the RRI, a non-invasive procedure, to determine the progression of AKI stages and the need for renal replacement therapy in patients hospitalised in intensive care units.",[65,66],"Akut Kidney Injury","Renal Replacement Therapy for Acute Kidney Injury in ICU",[68,69,70,71],"akut kidney injury","renal resistive index","renal replacement therapy","intensive care","2025-05-27",{"date":74,"type":75},"2025-05-29","ACTUAL",{"date":77,"type":75},"2025-01-01",{"date":79,"type":60},"2026-07-01",{"name":5,"class":6},1]