[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100621174":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":20,"locations":29,"responsibleParty":44,"collaborators":10,"id":46,"slug":47,"hasResults":48,"nctId":49,"briefTitle":50,"officialTitle":50,"acronym":10,"eligibilityCriteria":51,"healthyVolunteers":48,"sex":52,"minAge":53,"maxAge":54,"enrollmentInfo":55,"targetDuration":10,"studyType":58,"phases":10,"briefSummary":59,"conditions":60,"keywords":65,"overallStatus":72,"whyStopped":10,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":82},{"fullName":5,"class":6},"Marmara University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients Receiving Treatment for Lumbar Disc Herniation-Related Radiculopathy",null,"Adult patients with lumbar disc herniation-related radiculopathy undergoing routine fluoroscopy-guided transforaminal epidural steroid injection as part of standard clinical care, followed prospectively for pain outcomes.",[13],"Procedure: Transforaminal epidural steroid injection",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"PROCEDURE","Transforaminal epidural steroid injection","Fluoroscopy-guided transforaminal epidural steroid injection performed as part of routine clinical care. After confirmation of correct needle placement with contrast medium and exclusion of intravascular uptake, a mixture of betamethasone, bupivacaine, and normal saline is injected slowly into the epidural space. This procedure is not assigned by the study and is performed according to standard clinical practice.",[9],[21,26],{"name":22,"role":23,"phone":24,"phoneExt":10,"email":25},"Oguzhan Kasimoglu","CONTACT","+90 5448911835","kasimogluoguzhan@gmail.com",{"name":27,"role":23,"phone":10,"phoneExt":10,"email":28},"Savas Sencan","savas-44@hotmail.com",[30],{"facility":31,"status":10,"city":32,"state":10,"zip":10,"country":33,"countryCode":10,"cosmosGeoPoint":34,"geoPoint":39,"contacts":40},"Marmara Üniversitesi Tıp Fakültesi, Istanbul, Maltepe 34854","Istanbul","Turkey (Türkiye)",{"type":35,"coordinates":36},"Point",[37,38],28.94966,41.01384,{"lat":38,"lon":37},[41],{"name":42,"role":23,"phone":43,"phoneExt":10,"email":25},"Secretary General Secretary","+90 2166254545",{"type":45,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100621174","the-role-of-temporal-changes-in-pain-response-after-transforaminal-epidural-steroid-injection-on-treatment-success-100621174",false,"NCT07367191","The Role of Temporal Changes in Pain Response After Transforaminal Epidural Steroid Injection on Treatment Success","Inclusion Criteria:\n\n* Age between 18 and 65 years\n* Pre-procedural Numeric Rating Scale (NRS) pain score of 4 or higher\n* Presence of segmental lumbar disc herniation demonstrated on magnetic resonance imaging (MRI) consistent with clinical findings\n* Undergoing fluoroscopy-guided transforaminal epidural steroid injection due to insufficient response to conservative treatments, as determined by the algology clinic\n\nExclusion Criteria:\n\n* Presence of spondylolisthesis, scoliosis, or lumbar spinal stenosis accompanying lumbar disc herniation\n* Presence of malignancy\n* History of lumbar spine surgery for disc herniation\n* Transforaminal epidural steroid injection within the previous 6 months\n* Requirement for repeat epidural steroid injection during the data collection or follow-up period\n* Inability to be contacted for follow-up assessments by telephone","ALL","18 Years","65 Years",{"count":56,"type":57},120,"ESTIMATED","OBSERVATIONAL","Transforaminal epidural steroid injection (TFESI) is a commonly used minimally invasive procedure for the treatment of lumbar radicular pain secondary to disc herniation. Although TFESI has been shown to provide significant pain relief in a substantial proportion of patients, the onset, duration, and temporal pattern of pain relief after the procedure vary considerably among individuals. The relationship between early pain response patterns and long-term treatment success remains poorly understood.\n\nThis prospective observational study aims to evaluate whether temporal changes in pain intensity following TFESI, particularly during the early post-procedural period, are associated with clinical treatment success at mid- and long-term follow-up. Pain intensity will be assessed using the Numeric Rating Scale (NRS) at predefined time points following the procedure, and treatment success will be defined as a ≥50% reduction in NRS score compared with baseline.",[61,62,63,64],"Lumbar Disc Herniation","Lumbar Radiculopathy","Radicular Low Back Pain","Sciatica",[66,67,68,69,70,71],"TFESI","Temporal Pain Response","Numeric Rating Scale","NRS","Transforaminal Epidural Steroid Injection","Treatment Success","NOT_YET_RECRUITING","2026-01-16",{"date":75,"type":76},"2026-01-26","ACTUAL",{"date":78,"type":57},"2026-02-15",{"date":80,"type":57},"2026-10-15",{"name":5,"class":6},1]