[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100623796":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":21,"locations":30,"responsibleParty":81,"collaborators":20,"id":85,"slug":86,"hasResults":87,"nctId":88,"briefTitle":89,"officialTitle":89,"acronym":20,"eligibilityCriteria":90,"healthyVolunteers":87,"sex":91,"minAge":20,"maxAge":20,"enrollmentInfo":92,"targetDuration":20,"studyType":95,"phases":96,"briefSummary":98,"conditions":99,"keywords":20,"overallStatus":101,"whyStopped":20,"lastUpdateSubmitDate":102,"lastUpdatePostDateStruct":103,"startDateStruct":106,"completionDateStruct":108,"leadSponsor":110,"locationsCount":111},{"fullName":5,"class":6},"Vance Thompson Vision","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Treated Group","EXPERIMENTAL","Patients treated with DSLT",[13],"Device: Direct selective laser trabeculoplasty",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DEVICE","Direct selective laser trabeculoplasty","A non-invasive laser procedure for treating glaucoma and ocular hypertension by improving the eye's natural fluid drainage",[9],null,[22,27],{"name":23,"role":24,"phone":25,"phoneExt":20,"email":26},"Lorraine Provencher, MD","CONTACT","402-506-9970","lorraine.provencher@vancethompsonvision.com",{"name":28,"role":24,"phone":25,"phoneExt":20,"email":29},"Dana Dubas","dana.dubas@vancethompsonvision.com",[31,51,64],{"facility":5,"status":20,"city":32,"state":33,"zip":34,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"Alexandria","Minnesota","56308","United States","US",{"type":38,"coordinates":39},"Point",[40,41],-95.37754,45.88524,{"lat":41,"lon":40},[44,48],{"name":45,"role":24,"phone":46,"phoneExt":20,"email":47},"Deborah Ristvedt, DO","(320) 762-2166","deborah.ristvedt@vancethompsonvision.com",{"name":49,"role":24,"phone":46,"phoneExt":20,"email":50},"Miranda Danielson","miranda.danielson@vancethompsonvision.com",{"facility":5,"status":20,"city":52,"state":53,"zip":54,"country":35,"countryCode":36,"cosmosGeoPoint":55,"geoPoint":59,"contacts":60},"Omaha","Nebraska","68137",{"type":38,"coordinates":56},[57,58],-95.94043,41.25626,{"lat":58,"lon":57},[61,63],{"name":23,"role":24,"phone":62,"phoneExt":20,"email":26},"4025069970",{"name":28,"role":24,"phone":62,"phoneExt":20,"email":20},{"facility":5,"status":20,"city":65,"state":66,"zip":67,"country":35,"countryCode":36,"cosmosGeoPoint":68,"geoPoint":72,"contacts":73},"Fargo","North Dakota","58078",{"type":38,"coordinates":69},[70,71],-96.7898,46.87719,{"lat":71,"lon":70},[74,78],{"name":75,"role":24,"phone":76,"phoneExt":20,"email":77},"Michael Greenwood, MD","(701) 566-5390","michael.greenwood@vancethompsonvision.com",{"name":79,"role":24,"phone":76,"phoneExt":20,"email":80},"McKenzie Schueller","mckenzie.schueller@vancethompsonvision.com",{"type":82,"investigatorFullName":83,"investigatorTitle":84,"investigatorAffiliation":5,"oldNameTitle":20,"oldOrganization":20},"PRINCIPAL_INVESTIGATOR","Lorraine Provencher","Sponsor-Investigator","100623796","the-safety-and-efficacy-of-direct-slt-in-pseudoexfoliation-glaucoma-100623796",false,"NCT07401290","The Safety and Efficacy of Direct SLT in Pseudoexfoliation Glaucoma","Inclusion Criteria:\n\n* Adult patients diagnosed with pseudoexfoliation glaucoma (PXFG), with optic neuropathy consistent with glaucomatous damage of any severity\n* Open iridocorneal angle by gonioscopy, defined as a Shafer Grade II or greater\n* Treatment naive, or washed out IOP ranging from ≥18-35 mmHg\n* Able to complete medication washout safely and all follow-up visits\n* Participants must have a best correct visual acuity of 20\u002F40 or better in the study eye(s), be able to undertake a reliable Humphrey visual field (HVF) (defined as fixation losses, false positives and false negatives less than 33%), and must have field loss no worse than -20 dB in treatment eye\n\nExclusion Criteria:\n\n* Any contraindication to SLT or unable to have DSLT\n* Angle closure glaucoma or any other types of glaucoma other than PXFG\n* Prior incisional glaucoma surgery or glaucoma-related procedures in the study eye\n* Any prior refractive surgery\n* H\u002Fo LPI within last 6 months\n* A history of any significant cataract required during study duration or cataract surgery in the last 6 months\n* Prior laser trabeculoplasty (ALT\u002FSLT)\n* History of ocular inflammation and infection\n* Patients who are pregnant or have any clinically relevant systemic disease that may prevent them from reliably completing follow-up visits\n* Vulnerable populations that cannot provide proper informed consent will not be enrolled, such as children, prisoners, handicapped, or mentally disabled persons, or economically or educationally disadvantaged persons","ALL",{"count":93,"type":94},40,"ESTIMATED","INTERVENTIONAL",[97],"NA","Prospective, multi-center, single arm, interventional study evaluating DSLT in patients with pseudoexfoliative glaucoma.",[100],"Pseudoexfoliation Glaucoma","NOT_YET_RECRUITING","2026-02-03",{"date":104,"type":105},"2026-02-10","ACTUAL",{"date":107,"type":94},"2026-03",{"date":109,"type":94},"2028-03",{"name":5,"class":6},3]