[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100496892":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":19,"centralContacts":23,"locations":29,"responsibleParty":51,"collaborators":10,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":59,"eligibilityCriteria":60,"healthyVolunteers":55,"sex":61,"minAge":10,"maxAge":10,"enrollmentInfo":62,"targetDuration":10,"studyType":65,"phases":10,"briefSummary":66,"conditions":67,"keywords":10,"overallStatus":32,"whyStopped":10,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":79},{"fullName":5,"class":6},"Imperial College London","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Cardiomyopathies",null,"Approximately 1000 participants recruited prospectively from participating sites with a diagnosis of cardiomyopathy\n\nParticipants will provide biosamples and allow access to medical scans and records for health data collection",[13],"Other: Blood Sample Collection",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"Blood Sample Collection","Blood for DNA and biomarker analysis",[9],[20],{"name":21,"affiliation":5,"role":22},"James Ware","PRINCIPAL_INVESTIGATOR",[24],{"name":25,"role":26,"phone":27,"phoneExt":10,"email":28},"Study Coordinator","CONTACT","02073528121","smarter-cm@imperial.ac.uk",[30,44],{"facility":31,"status":32,"city":33,"state":10,"zip":10,"country":34,"countryCode":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":42},"Guys & St Thomas' NHS Foundation Trust","RECRUITING","London","United Kingdom","UK",{"type":37,"coordinates":38},"Point",[39,40],-0.12574,51.50853,{"lat":40,"lon":39},[43],{"name":10,"role":26,"phone":10,"phoneExt":10,"email":28},{"facility":45,"status":32,"city":33,"state":10,"zip":10,"country":34,"countryCode":35,"cosmosGeoPoint":46,"geoPoint":48,"contacts":49},"Kings College Hospital",{"type":37,"coordinates":47},[39,40],{"lat":40,"lon":39},[50],{"name":10,"role":26,"phone":10,"phoneExt":10,"email":28},{"type":52,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100496892","the-smarter-cardiomyopathy-study-100496892",false,"NCT05750147","The SMARTER Cardiomyopathy Study","Genetics, Imaging and Artificial Intelligence for Precision Care in Cardiomyopathy","SMARTER-CM","Inclusion Criteria:\n\nAdults with the capacity to consent Children with parental\u002Fguardian consent Male and Female\n\nMeeting the following criteria:\n\n1. Patients with a confirmed diagnosis of cardiomyopathy or related condition\n2. Patients with a family member with cardiomyopathy, or a related condition\n3. Patients with a genetic variant that may predispose to cardiomyopathy, or a related condition\n\nExclusion Criteria:\n\nPatients without the capacity to provide informed consent","ALL",{"count":63,"type":64},1000,"ESTIMATED","OBSERVATIONAL","Cardiomyopathies are diseases of the heart muscle. Known genetic factors may account for some cardiomyopathy cases but there is still much to understand about the genetic and environmental causes and how the disease progresses.\n\nFinding new ways to diagnose and treat cardiomyopathies could improve the health and well-being of patients with these conditions.\n\nThis study will collect data from individuals with cardiomyopathy or related heart muscle disease, or with a possible genetic predisposition to cardiomyopathy, and follow them over time to observe the progress of their heart and health. This study will collect DNA, blood samples, and detailed clinical \\& lifestyle information at the start of the study, and data collected during routine healthcare visits over time.\n\n* learn what causes cardiomyopathy, and therefore how to treat it\n* understand why cardiomyopathy progresses differently in different people, to improve the ability to recognise who will benefit from different treatments at different times\n\nThe investigators will collaborate with other centres internationally to collect a large of group of participants with similar cardiomyopathies, providing power to identify new pathways that cause disease and ways of predicting which participants are at risk of having more severe disease.",[9,68,69],"Hypertrophic Cardiomyopathy","Dilated Cardiomyopathy","2024-03-05",{"date":72,"type":73},"2024-03-06","ACTUAL",{"date":75,"type":73},"2023-03-01",{"date":77,"type":64},"2027-08-01",{"name":5,"class":6},2]