[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100605855":3},{"organization":4,"armGroups":7,"interventions":33,"overallOfficials":57,"centralContacts":61,"locations":70,"responsibleParty":87,"collaborators":89,"id":93,"slug":94,"hasResults":95,"nctId":96,"briefTitle":97,"officialTitle":98,"acronym":39,"eligibilityCriteria":99,"healthyVolunteers":100,"sex":101,"minAge":102,"maxAge":39,"enrollmentInfo":103,"targetDuration":39,"studyType":106,"phases":107,"briefSummary":109,"conditions":110,"keywords":39,"overallStatus":111,"whyStopped":39,"lastUpdateSubmitDate":112,"lastUpdatePostDateStruct":113,"startDateStruct":116,"completionDateStruct":118,"leadSponsor":120,"locationsCount":121},{"fullName":5,"class":6},"University of Wisconsin, Madison","OTHER",[8,14,20,24,27,30],{"label":9,"type":10,"description":11,"interventionNames":12},"Healthy Participants - Scan Efficiency","EXPERIMENTAL","Participants not otherwise undergoing a brain MRI",[13],"Device: Brain MRI - SOC and spiral",{"label":15,"type":16,"description":17,"interventionNames":18},"Standard of Care (SOC) Brain MRI","ACTIVE_COMPARATOR","Participants undergoing SOC MRI",[19],"Device: Brain MRI",{"label":21,"type":10,"description":11,"interventionNames":22},"Healthy Participants - Tau",[23],"Device: Brain MRI - spiral",{"label":25,"type":10,"description":11,"interventionNames":26},"Healthy Participants - image quality",[13],{"label":28,"type":10,"description":11,"interventionNames":29},"Healthy Participants - SNR",[23],{"label":31,"type":10,"description":11,"interventionNames":32},"Healthy Participants - Gradient Derating",[23],[34,40,44,48,51,54],{"type":35,"name":36,"description":37,"armGroupLabels":38,"otherNames":39},"DEVICE","Brain MRI","90 participants will undergo a 60 minute SOC brain MRI followed by 15 minute spiral MRI",[15],null,{"type":35,"name":41,"description":42,"armGroupLabels":43,"otherNames":39},"Brain MRI - SOC and spiral","6 participants will be scanned using 2 versions (SOC and spiral) pf 6 sequences (12 scans total).",[9],{"type":35,"name":45,"description":46,"armGroupLabels":47,"otherNames":39},"Brain MRI - spiral","10 participants will be scanned with 3 sequences, 3 times (9 total scans per participants)",[21],{"type":35,"name":41,"description":49,"armGroupLabels":50,"otherNames":39},"10 participants will be scanned using 2 versions (SOC and spiral) of 6 sequences (12 scans total).",[25],{"type":35,"name":45,"description":52,"armGroupLabels":53,"otherNames":39},"10 participants will be scanned with 3 spiral sequences to achieve desired signal to noise ratio (SNR).",[28],{"type":35,"name":45,"description":55,"armGroupLabels":56,"otherNames":39},"5 participants will be scanned with 2 pairs of 6 spiral sequences.",[31],[58],{"name":59,"affiliation":5,"role":60},"James Pipe, PhD","PRINCIPAL_INVESTIGATOR",[62,67],{"name":63,"role":64,"phone":65,"phoneExt":39,"email":66},"Study Coordinator","CONTACT","608-282-8349","Radstudy@uwhealth.org",{"name":68,"role":64,"phone":39,"phoneExt":39,"email":69},"Suzanne Hanson","shanson@uwhealth.org",[71],{"facility":72,"status":39,"city":73,"state":74,"zip":75,"country":76,"countryCode":77,"cosmosGeoPoint":78,"geoPoint":83,"contacts":84},"University of Wisconsin - Madison","Madison","Wisconsin","53705","United States","US",{"type":79,"coordinates":80},"Point",[81,82],-89.40123,43.07305,{"lat":82,"lon":81},[85,86],{"name":63,"role":64,"phone":65,"phoneExt":39,"email":66},{"name":59,"role":60,"phone":39,"phoneExt":39,"email":39},{"type":88,"investigatorFullName":39,"investigatorTitle":39,"investigatorAffiliation":39,"oldNameTitle":39,"oldOrganization":39},"SPONSOR",[90],{"name":91,"class":92},"National Institute for Biomedical Imaging and Bioengineering (NIBIB)","NIH","100605855","the-spiral-mri-study-100605855",false,"NCT07167953","The Spiral MRI Study","MRI Technology for Greater Efficiency and Improved Value","Healthy Controls Inclusion Criteria:\n\n* Adults at least 18 years\n* Able to provide written informed consent on their own behalf\n\nBrain MR Inclusion Criteria:\n\n* Adults at least 18 years\n* Able to provide written informed consent on their own behalf\n* Scheduled for standard of care brain MRI\n\nExclusion Criteria (ALL):\n\n* Unable or unwilling to provide informed consent\n* Contraindication(s) to or inability to undergo MRI\n* Currently pregnant\n* Participants requiring intravenous (IV) conscious sedation for imaging are not eligible; participants requiring mild, oral anxiolytics for the clinical MRI will be allowed as long as the following criteria are met:\n* participant has their own prescription for the medication\n* informed consent process is conducted prior to the self-administration of the medication\n* they come to the research visit with a driver",true,"ALL","18 Years",{"count":104,"type":105},131,"ESTIMATED","INTERVENTIONAL",[108],"NA","The goal of this clinical trial is to find out if new Magnetic Resonance Imaging (MRI) computer software will:\n\n* help make scans and exams faster\n* reduce artifacts\n* make MRI easier to understand\n* allow technicians to focus more on the participant and less on the scanner\n\nParticipants will complete one brain MRI imaging session, lasting about 60 minutes.",[36],"NOT_YET_RECRUITING","2026-06-30",{"date":114,"type":115},"2026-07-01","ACTUAL",{"date":117,"type":105},"2028-08",{"date":119,"type":105},"2031-05",{"name":5,"class":6},1]