[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100590928":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":10,"centralContacts":26,"locations":32,"responsibleParty":50,"collaborators":54,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":10,"eligibilityCriteria":62,"healthyVolunteers":63,"sex":64,"minAge":65,"maxAge":66,"enrollmentInfo":67,"targetDuration":10,"studyType":70,"phases":71,"briefSummary":73,"conditions":74,"keywords":78,"overallStatus":83,"whyStopped":10,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"Peking Union Medical College Hospital","OTHER",[8,13],{"label":9,"type":6,"description":10,"interventionNames":11},"Patients planned for partial nephrectomy due to renal tumors",null,[12],"Diagnostic Test: GFR will be measured using three methods at two weeks before surgery and four ± one week after surgery",{"label":14,"type":6,"description":10,"interventionNames":15},"Subjects with varying levels of renal function and no history of renal tumors",[16],"Diagnostic Test: GFR will be measured using three methods: [68Ga]Ga-HBED-CC-DiAsp PET\u002FCT, the Gates method, and the dual plasma sampling method with 99mTc-DTPA.",[18,22],{"type":19,"name":20,"description":20,"armGroupLabels":21,"otherNames":10},"DIAGNOSTIC_TEST","GFR will be measured using three methods at two weeks before surgery and four ± one week after surgery",[9],{"type":19,"name":23,"description":24,"armGroupLabels":25,"otherNames":10},"GFR will be measured using three methods: [68Ga]Ga-HBED-CC-DiAsp PET\u002FCT, the Gates method, and the dual plasma sampling method with 99mTc-DTPA.","GFR will be measured using three methods: \\[68Ga\\]Ga-HBED-CC-DiAsp PET\u002FCT, the Gates method, and the dual plasma sampling method with 99mTc-DTPA.",[14],[27],{"name":28,"role":29,"phone":30,"phoneExt":10,"email":31},"Yaping Luo, MD","CONTACT","86-010-69154716","luoyaping@live.com",[33],{"facility":5,"status":10,"city":34,"state":35,"zip":36,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"Beijing","Beijing Municipality","100730","China","CN",{"type":40,"coordinates":41},"Point",[42,43],116.39723,39.9075,{"lat":43,"lon":42},[46],{"name":47,"role":29,"phone":48,"phoneExt":10,"email":49},"Jiayue Li","86-010-69156874","xs@abscd.com",{"type":51,"investigatorFullName":52,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"SPONSOR_INVESTIGATOR","Luo Yaping","Medical Doctor (M.D.), Chief Physician, Professor, Assistant Director",[55],{"name":5,"class":6},"100590928","the-study-on-the-effectiveness-of-68gaga-hbed-cc-diasp-petct-in-calculating-gfr-and-predicting-residual-renal-function-after-partial-nephrectomy-100590928",false,"NCT06973798","The Study on the Effectiveness of [68Ga]Ga-HBED-CC-DiAsp PET\u002FCT in Calculating GFR and Predicting Residual Renal Function After Partial Nephrectomy","The Study on the Effectiveness of [68Ga]Ga-HBED-CC-DiAsp PET\u002FCT in Calculating Glomerular Filtration Rate and Predicting Residual Renal Function After Partial Nephrectomy","Inclusion Criteria:\n\n* Age \\> 18 years;\n* Written informed consent obtained.\n\nExclusion Criteria:\n\n* Patients with claustrophobia or fear of radiation;\n* Women who are planning to conceive, pregnant, or breastfeeding;\n* Patients unable to lie flat for 30 minutes;\n* Patients or family members who cannot understand the conditions and objectives of the study, or who refuse to participate.",true,"ALL","18 Years","88 Years",{"count":68,"type":69},40,"ESTIMATED","INTERVENTIONAL",[72],"NA","In subjects with different levels of renal function and no history of renal tumors, GFR is measured using \\[68Ga\\]Ga-HBED-CC-DiAsp PET\u002FCT, the Gates method, and the 99mTc-DTPA dual plasma method. The consistency between the three methods is analyzed using intra-class correlation coefficient (ICC), concordance correlation coefficient (CCC), and Bland-Altman analysis.\n\nIn patients scheduled for partial nephrectomy due to renal tumors, GFR is measured using the three methods within 2 weeks before surgery and 4±1 weeks post-surgery. The percentage of postoperative residual renal function (postoperative GFR\u002Fpreoperative GFR × 100%, hereafter referred to as RRF%) is calculated for each method. By comparing and overlaying preoperative and postoperative PET\u002FCT images, the resected renal area can be delineated on the preoperative PET\u002FCT image. Based on the preoperative PET\u002FCT and the delineated surgical area, a predictive value for postoperative GFR is calculated to obtain the predicted RRF%. A consistency analysis is then performed between the predicted RRF% and the actual RRF% measured by the three methods, using ICC, CCC, and Bland-Altman analysis to evaluate the efficacy of \\[68Ga\\]Ga-HBED-CC-DiAsp PET\u002FCT in predicting residual renal function after partial nephrectomy.",[75,76,77],"Kidney Neoplasms \u002F Surgery","Glomerular Filtration Rate","Positron-Emission Tomography(PET)",[79,80,81,82],"[68Ga]Ga-HBED-CC-DiAsp","PET\u002FCT","glomerular filtration rate","partial nephrectomy","NOT_YET_RECRUITING","2025-05-07",{"date":86,"type":87},"2025-05-15","ACTUAL",{"date":89,"type":69},"2025-07-01",{"date":91,"type":69},"2025-11-10",{"name":52,"class":6},1]