[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100560183":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":24,"locations":31,"responsibleParty":51,"collaborators":10,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":57,"acronym":10,"eligibilityCriteria":58,"healthyVolunteers":59,"sex":60,"minAge":61,"maxAge":10,"enrollmentInfo":62,"targetDuration":10,"studyType":65,"phases":10,"briefSummary":66,"conditions":67,"keywords":69,"overallStatus":74,"whyStopped":10,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"University Hospital Ostrava","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Microbiome in healthy volunteers",null,"Healthy volunteers willing to provide blood and urine samples for microbiome evaluation",[13],"Diagnostic Test: Blood and urine sample evaluation",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"DIAGNOSTIC_TEST","Blood and urine sample evaluation","Blood and urine sample evaluation will be performed in healthy female volunteers.",[9],[21],{"name":22,"affiliation":5,"role":23},"Jan Krhut, prof.,MD,PhD","PRINCIPAL_INVESTIGATOR",[25],{"name":26,"role":27,"phone":28,"phoneExt":29,"email":30},"Jiří Hynčica","CONTACT","0042059737","2587","jiri.hyncica@fno.cz",[32],{"facility":5,"status":10,"city":33,"state":34,"zip":35,"country":36,"countryCode":10,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"Ostrava","Moravian-Silesian Region","70852","Czechia",{"type":38,"coordinates":39},"Point",[40,41],18.28204,49.83465,{"lat":41,"lon":40},[44,45,46,49],{"name":26,"role":27,"phone":28,"phoneExt":29,"email":30},{"name":22,"role":23,"phone":10,"phoneExt":10,"email":10},{"name":47,"role":48,"phone":10,"phoneExt":10,"email":10},"Tomáš Rychlý, MD","SUB_INVESTIGATOR",{"name":50,"role":48,"phone":10,"phoneExt":10,"email":10},"Kateřína Ryšánková, MD,PhD",{"type":52,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100560183","the-urinary-microbiome-and-its-relationship-to-the-urinary-and-serum-metabolome-in-healthy-peri--and-postmenopausal-women-100560183",false,"NCT06573827","The Urinary Microbiome and Its Relationship to the Urinary and Serum Metabolome in Healthy Peri- and Postmenopausal Women","Inclusion Criteria:\n\n* Women over 50 years old\n* Consent to participate in the study\n* Willingness to take urine and blood samples according to the protocol\n\nExclusion Criteria:\n\n* Known congenital developmental defects of the urinary tract (congenital hydronephrosis, vesicoureteral reflux, renal agenesis, and hypoplasia, multicystic and polycystic kidneys)\n* Recurrent urinary tract infections (more than 3 episodes in the last 12 months)\n* Presence of any lower-urinary tract symptoms (urgency, frequency, incontinence, stranguria, urge to urinate, weak urine stream, the feeling of post-micturition residue)\n* The presence of a foreign body in the urinary tract - urolithiasis, urinary catheter, ureteral stent\n* Acute or chronic diseases with possible influence on lower-urinary tract function\n* Medications with possible influence on lower-urinary tract function\n* Rheumatoid arthritis\n* Diabetes mellitus",true,"FEMALE","50 Years",{"count":63,"type":64},100,"ESTIMATED","OBSERVATIONAL","The presented project aims to characterize the microbiome of healthy peri- and postmenopausal women and its correlation with the metabolome of urine and serum.",[68],"Urinary Tract Infections",[70,71,72,73],"microbiome","urinary metabolome","urinary bladder","menopause","NOT_YET_RECRUITING","2024-08-23",{"date":77,"type":78},"2024-08-27","ACTUAL",{"date":80,"type":64},"2024-09-01",{"date":82,"type":64},"2028-12-31",{"name":5,"class":6},1]