[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100634125":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":15,"locations":24,"responsibleParty":82,"collaborators":86,"id":94,"slug":95,"hasResults":96,"nctId":97,"briefTitle":98,"officialTitle":99,"acronym":10,"eligibilityCriteria":100,"healthyVolunteers":101,"sex":102,"minAge":103,"maxAge":104,"enrollmentInfo":105,"targetDuration":10,"studyType":108,"phases":10,"briefSummary":109,"conditions":110,"keywords":119,"overallStatus":27,"whyStopped":10,"lastUpdateSubmitDate":124,"lastUpdatePostDateStruct":125,"startDateStruct":128,"completionDateStruct":130,"leadSponsor":132,"locationsCount":133},{"fullName":5,"class":6},"Aalborg University Hospital","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Children with Daytime Urinary Incontinence",null,"Children, aged 5-17 years, who suffers from overactive bladder (OAB) and daytime urinary incontinence (DUI).",{"label":13,"type":10,"description":14,"interventionNames":10},"Healthy children","Children, aged 5-17 years, who are healthy and have no bladder symptoms.",[16,21],{"name":17,"role":18,"phone":19,"phoneExt":10,"email":20},"Kristina Thorsteinsson, MD","CONTACT","+4597663372","uroforsk@rn.dk",{"name":22,"role":18,"phone":23,"phoneExt":10,"email":20},"Søren Hagstrøm, MD, PhD","+4597663400",[25,40,55,69],{"facility":26,"status":27,"city":28,"state":10,"zip":29,"country":30,"countryCode":31,"cosmosGeoPoint":32,"geoPoint":37,"contacts":38},"Department of Pediatrics, Aalborg University Hospital","RECRUITING","Aalborg","9000","Denmark","DK",{"type":33,"coordinates":34},"Point",[35,36],9.9187,57.048,{"lat":36,"lon":35},[39],{"name":17,"role":18,"phone":19,"phoneExt":10,"email":20},{"facility":41,"status":42,"city":43,"state":10,"zip":44,"country":30,"countryCode":31,"cosmosGeoPoint":45,"geoPoint":49,"contacts":50},"Department of Pediatrics, Aarhus University Hospital","NOT_YET_RECRUITING","Aarhus","8200",{"type":33,"coordinates":46},[47,48],10.21076,56.15674,{"lat":48,"lon":47},[51],{"name":52,"role":18,"phone":53,"phoneExt":10,"email":54},"Konstantinos Kamperis, MD, PhD","+4578450000","kostas.kamperis@clin.au.dk",{"facility":56,"status":27,"city":57,"state":10,"zip":58,"country":30,"countryCode":31,"cosmosGeoPoint":59,"geoPoint":63,"contacts":64},"Department of Pediatrics, Regional Hospital West Jutland","Herning","7400",{"type":33,"coordinates":60},[61,62],8.97662,56.13615,{"lat":62,"lon":61},[65],{"name":66,"role":18,"phone":67,"phoneExt":10,"email":68},"Luise Borch, MD, PhD","+4578430000","luise.borch@rm.dk",{"facility":70,"status":42,"city":71,"state":10,"zip":72,"country":30,"countryCode":31,"cosmosGeoPoint":73,"geoPoint":77,"contacts":78},"Department of Pediatrics, North Denmark Regional Hospital","Hjørring","9800",{"type":33,"coordinates":74},[75,76],9.98229,57.46417,{"lat":76,"lon":75},[79],{"name":80,"role":18,"phone":10,"phoneExt":10,"email":81},"Mette Line Roed, MD, PhD","mld@rn.dk",{"type":83,"investigatorFullName":84,"investigatorTitle":85,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Kristina Thorsteinsson","Principal investigator",[87,89,91],{"name":88,"class":6},"Aarhus University Hospital",{"name":90,"class":6},"Regional Hospital West Jutland",{"name":92,"class":93},"Regionshospital Nordjylland","OTHER_GOV","100634125","the-voided-urinary-perineal-and-faecal-microbiota-among-children-and-adolescents---the-ppuf-study-100634125",false,"NCT07535619","The Voided Urinary, Perineal, and Faecal Microbiota Among Children and Adolescents - the PpUF-study.","The Voided Urinary, Perineal, and Faecal Microbiota Among Children and Adolescents With Overactive Bladder and Daytime Urinary Incontinence and Healthy Children and Adolescents - the PpUF-study.","Inclusion Criteria:\n\n* Overactive bladder as per International Children's Continence Society criteria (cases only).\n* At least two wet days per week (cases only).\n* No prior pharmacological treatment of OAB and DUI (cases only).\n* No lower urinary tract symptoms (healthy participants only).\n* Negative urine dipstick test\n\nExclusion Criteria:\n\n* No known urogenital abnormality affecting the lower urinary tract function.\n* No known gastrointestinal or neurological diseases.\n* No use of systemic drugs within five half-lives of the drug.\n* No use of systemic antibiotics within three months before inclusion\n* No current urinary tract infection.\n* No urinary tract infection within the last three months prior to inclusion.\n* No current constipation.\n* Abnormal uroflowmetry (healthy participants only).",true,"ALL","5 Years","17 Years",{"count":106,"type":107},110,"ESTIMATED","OBSERVATIONAL","The aim of this study is to investigate whether the voided urinary, perineal\u002Fpreputial, and the fecal microbiota are different between children suffering from Overactive Bladder (OAB) and Daytime Urinary Incontinence (DUI) compared to age- and gender-matched healthy children without bladder symptoms. Moreover, the study aims to investigate if the microbiota is different according to the severity of DUI and if the microbiota is changed throughout treatment of DUI. A follow-up study will as well be performed on healthy children to investigate how the microbiota evolves with increasing age and pubertal stage. Children with OAB and DUI will be recruited from involved pediatric departments, and specimen in the form of urine, perineal\u002Fpreputial swabs, and feces will be collected according to the protocol.",[111,112,113,114,115,116,117,118],"Urinary Incontinence","Daytime Wetting","Urination Disorders","Urologic Diseases","Lower Urinary Tract Symptoms","Urological Manifestations","Elimination Disorders","Behavioral Symptoms",[120,121,122,123],"Voided Urinary Microbiota","Perineal Microbiota","Fecal Microbiota","Illumina MiSeq Sequencing","2026-04-15",{"date":126,"type":127},"2026-04-17","ACTUAL",{"date":129,"type":127},"2022-12-14",{"date":131,"type":107},"2028-06",{"name":5,"class":6},4]