[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100630012":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":17,"centralContacts":24,"locations":30,"responsibleParty":50,"collaborators":17,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":59,"eligibilityCriteria":60,"healthyVolunteers":55,"sex":61,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":17,"studyType":67,"phases":68,"briefSummary":70,"conditions":71,"keywords":73,"overallStatus":33,"whyStopped":17,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"Zhongda Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"the electroacupuncture group","ACTIVE_COMPARATOR","receive treatment at Zusanli every other day",[13],"Procedure: Electroacupuncture at Zusanli (ST-36)",{"label":15,"type":16,"description":17,"interventionNames":17},"Usual Care Group","NO_INTERVENTION",null,[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":17},"PROCEDURE","Electroacupuncture at Zusanli (ST-36)","The primary acupuncture point is Zusanli (ST-36). Depending on the location of the gangrenous lesion, 1 to 2 additional local acupoints are chosen on intact skin near the affected area as adjunct points. After routine sterilization of the acupoint area, disposable sterile acupuncture needles (0.3 × 40 mm) are inserted perpendicularly to a depth of approximately 1 cun. An XS-998C photoelectric therapy device is used with a dense-sparse wave at frequency setting f1. The current intensity is adjusted to a level tolerable for the participant. Treatment is administered for 6 consecutive days, followed by a 1-day break. A total of 4 weeks constitutes one treatment course.",[9],[25],{"name":26,"role":27,"phone":28,"phoneExt":17,"email":29},"Dachun Chen","CONTACT","13912992162","peoplechenda@126.com",[31],{"facility":32,"status":33,"city":34,"state":35,"zip":36,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"Zongda Hospital affiliated to Southeast University","RECRUITING","Nanjing","Jiangsu","210009","China","CN",{"type":40,"coordinates":41},"Point",[42,43],118.77778,32.06167,{"lat":43,"lon":42},[46],{"name":47,"role":27,"phone":48,"phoneExt":17,"email":49},"Huiping Wang","+86 25 83272015","zdll2015@163.com",{"type":51,"investigatorFullName":26,"investigatorTitle":52,"investigatorAffiliation":32,"oldNameTitle":17,"oldOrganization":17},"PRINCIPAL_INVESTIGATOR","Attending Physician of Traditional Chinese Medicine","100630012","therapeutic-effect-of-electroacupuncture-at-zusanli-st-36-on-diabetic-foot-wounds-100630012",false,"NCT07482137","Therapeutic Effect of Electroacupuncture at Zusanli (ST-36) on Diabetic Foot Wounds","Clinical Observation and Mechanism Study on the Therapeutic Effect of Electroacupuncture at Zusanli (ST-36) in Promoting Diabetic Foot Wound Healing Through Mediating Macrophage Polarization","EA for DFU","Inclusion Criteria:\n\n1. Meet the diagnostic criteria for diabetic foot ulcers;\n2. Meet the criteria for Traditional Chinese Medicine syndrome differentiation, classified as blood stasis obstructing the collateral pattern;\n3. Wagner Grade 1-3, with ulcer area ranging from 2 cm² to 30 cm²;\n4. Male or female, aged between 18 and 75 years;\n5. Provide signed informed consent, voluntarily participate in this study, and demonstrate good compliance.\n\nExclusion Criteria:\n\n1. Complicated with severe diseases of the brain, liver, heart, lungs, or kidneys;\n2. Pregnant women or women planning to become pregnant;\n3. Glycosylated hemoglobin (HbA1c) level ≥ 9%;\n4. Complicated with psychiatric disorders;\n5. Complicated with genetic or infectious diseases, malignant tumors, or other severe conditions associated with a short life expectancy;\n6. Concurrent participation in other clinical trials or participation within 4 weeks prior to randomization.","ALL","18 Years","75 Years",{"count":65,"type":66},76,"ESTIMATED","INTERVENTIONAL",[69],"NA","The goal of this clinical trial is to learn if electroacupuncture at the Zusanli (ST-36) can assist in the treatment of diabetic foot ulcers. The main question it aims to answer is: Can electroacupuncture at the Zusanli (ST-36) promote wound healing in patients with diabetic foot ulcers?\n\nResearchers will compare outcomes between participants receiving electroacupuncture plus standard treatment and those receiving standard treatment alone to assess the effect of Zusanli (ST36) stimulation on wound healing in patients with diabetic foot ulcers.\n\nParticipants will:\n\nReceive standard diabetes treatment (including diabetes education, dietary control, insulin combined with oral hypoglycemic agents to manage blood glucose, and effective antibiotics to control infection. For patients with foot ulcers, the wound will be cleaned with saline; abscesses will be drained if present; daily dressing changes.) Participants in the electroacupuncture group will receive electroacupuncture at Zusanli(ST-36) every day; 6 sessions constitute one treatment course, for a total of 4 courses.\n\nVisit the hospital for examinations before treatment and after each treatment course to measure the ankle-brachial index (ABI), assess diabetic foot Wagner grade, and evaluate hemodynamic parameters.",[72],"Diabetes Foot Care",[74,75],"Diabetic Foot Ulcers","Electroacupuncture","2026-03-15",{"date":78,"type":79},"2026-03-19","ACTUAL",{"date":81,"type":79},"2025-07-15",{"date":83,"type":66},"2027-12-31",{"name":5,"class":6},1]