[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100562743":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":10,"centralContacts":29,"locations":35,"responsibleParty":48,"collaborators":10,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":10,"eligibilityCriteria":58,"healthyVolunteers":54,"sex":59,"minAge":60,"maxAge":61,"enrollmentInfo":62,"targetDuration":65,"studyType":66,"phases":10,"briefSummary":67,"conditions":68,"keywords":70,"overallStatus":73,"whyStopped":10,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"China-Japan Friendship Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"surgery group",null,"patients treated with thyroidectomy for benign thyroid nodules",[13],"Procedure: surgery",{"label":15,"type":10,"description":16,"interventionNames":17},"thermal ablation group","patients treated with staged thermal ablation for benign thyroid nodules",[18],"Procedure: staged thermal ablation",[20,25],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":10},"PROCEDURE","surgery","patients undergo conventional\u002Fopen thyroidectomy or endoscopic thyroidectomy for large benign thyroid nodules",[9],{"type":21,"name":26,"description":27,"armGroupLabels":28,"otherNames":10},"staged thermal ablation","patients undergo multiple sessions of thermal ablation for large benign thyroid nodules",[15],[30],{"name":31,"role":32,"phone":33,"phoneExt":10,"email":34},"Ming-an Yu, MD","CONTACT","86-84205756","yma301@163.com",[36],{"facility":5,"status":10,"city":37,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":10},"Beijing","Beijing Municipality","100029","China","CN",{"type":43,"coordinates":44},"Point",[45,46],116.39723,39.9075,{"lat":46,"lon":45},{"type":49,"investigatorFullName":50,"investigatorTitle":51,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"SPONSOR_INVESTIGATOR","Ming-an Yu","Head of the Department of Interventional Medicine","100562743","thermal-ablation-vs-thyroidectomy-for-large-benign-thyroid-nodules-100562743",false,"NCT06607133","Thermal Ablation Vs Thyroidectomy for Large Benign Thyroid Nodules","Comparison of Staged Thermal Ablation and Thyroidectomy for Large Benign Thyroid Nodules","Inclusion Criteria:\n\n* benign thyroid nodules confirmed by surgical pathology in surgery group, and by two separate US-guided fine-needle aspiration (FNA) or core needle biopsy (CNB) in thermal ablation group;\n* the largest diameter of the nodule ≥4 cm;\n* the presence of nodule-related symptoms, cosmetic concerns, or psychological stress;\n* patients treated with surgery, or staged thermal ablation (who explicitly refused surgery);\n* more than 12-month follow-up duration\n\nExclusion Criteria:\n\n* suspicion of malignant nodule on ultrasound findings (e.g., marked hypoechoic, microcalcifications, or ill-defined margins);\n* comorbidities of other severe diseases;\n* without complete treatment and\u002For follow-up information","ALL","18 Years","80 Years",{"count":63,"type":64},300,"ESTIMATED","6 Months","OBSERVATIONAL","To compare the safety, efficacy and quality of life between staged thermal ablation and thyroidectomy in the treatment of Large benign thyroid nodules.",[69],"Benign Thyroid Nodules",[71,72],"thermal ablation","Thyroidectomy","NOT_YET_RECRUITING","2024-09-18",{"date":76,"type":77},"2024-09-23","ACTUAL",{"date":79,"type":64},"2024-09-10",{"date":81,"type":64},"2027-12",{"name":50,"class":6},1]