[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100639112":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":27,"centralContacts":32,"locations":11,"responsibleParty":42,"collaborators":11,"id":46,"slug":47,"hasResults":48,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":11,"eligibilityCriteria":52,"healthyVolunteers":48,"sex":53,"minAge":54,"maxAge":55,"enrollmentInfo":56,"targetDuration":11,"studyType":59,"phases":60,"briefSummary":62,"conditions":63,"keywords":65,"overallStatus":69,"whyStopped":11,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":11},{"fullName":5,"class":6},"Cairo University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"conventional retentive overlay design","EXPERIMENTAL",null,[13],"Other: hybrid ceramic retentive overlay",{"label":15,"type":10,"description":11,"interventionNames":16},"minimal invasive non-retentive overlay design",[17],"Other: hybrid ceramic non-retentive overlay",[19,23],{"type":6,"name":20,"description":21,"armGroupLabels":22,"otherNames":11},"hybrid ceramic retentive overlay","Endodontically treated molars will receive indirect overlay restorations utilizing a conventional retentive occlusal box cavity design.",[9],{"type":6,"name":24,"description":25,"armGroupLabels":26,"otherNames":11},"hybrid ceramic non-retentive overlay","Endodontically treated molars will receive indirect overlay restorations utilizing a minimal invasive anatomical non-retentive design.",[15],[28],{"name":29,"affiliation":30,"role":31},"Olfat ElSayed Hassanein, Professor","Conservative Dentistry, Faculty of Dentistry, Cairo University","STUDY_DIRECTOR",[33,39],{"name":34,"role":35,"phone":36,"phoneExt":37,"email":38},"Sara Ibrahim Fahmy, PhD","CONTACT","01006256086","002","sara.fahmy@dentistry.cu.edu.eg",{"name":40,"role":35,"phone":11,"phoneExt":11,"email":41},"Aya Mohamed Adly, Lecturer","aya.mohamed@dentistry.cu.edu.eg",{"type":43,"investigatorFullName":44,"investigatorTitle":45,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","Sara Ibrahim Mohamed Fahmy","part-time assistant lecturer","100639112","this-study-is-conducted-to-evaluate-the-clinical-performance-of-indirect-overlay-restorations-with-different-cavity-preparation-designs-in-endodontically-treated-molars-100639112",false,"NCT07614451","This Study is Conducted to Evaluate the Clinical Performance of Indirect Overlay Restorations With Different Cavity Preparation Designs in Endodontically Treated Molars.","A Prospective Clinical Evaluation of Indirect Overlay Restorations With Different Cavity Preparation Designs in Endodontically Treated Molars: Two Year Randomized Clinical Trial","Inclusion Criteria:\n\nPatient Related Criteria:\n\n* Adult patients (age: 20-60 years) of both genders.\n* Healthy patients (not suffering of any systematic or chronic diseases).\n* Able to tolerate the necessary restorative procedures.\n* Willing to sign the informed ethical consent.\n* Accepts the follow-up period.\n\nTooth Related Criteria:\n\n* Proper endodontically treated teeth.\n* First and second permanent molars.\n* Absence of any peri-apical lesions.\n* Absence of any periodontal disease involvement.\n* Large access cavities with one or two missing walls.\n* Patients with proper oral hygiene.\n* Presence of opposing tooth.\n\nExclusion Criteria:\n\n* Patient related:\n* Patients younger than 20 or older than 60 years old.\n* Pregnant females.\n* Patients with any systemic or chronic diseases.\n* Patients not accepting the follow-up period.\n* Patients not willing to sign the informed ethical consent.\n* Patients with known allergies to latex and\u002For resinous material.\n\nTooth related\n\n* Endodontically treated anterior, premolar and third molar teeth.\n* Hopelessly carious\u002Fdestructed teeth necessitating extraction.\n* Mobile teeth, indicating periodontal disease or trauma.\n* External or internal resorption.\n* Poor endodontic treatment.\n* Periapical lesion present.\n* Cervical carious lesions involved.","ALL","20 Years","60 Years",{"count":57,"type":58},50,"ESTIMATED","INTERVENTIONAL",[61],"NA","This study is conducted to evaluate the clinical performance of indirect overlay restorations with different cavity preparation designs in endodontically treated molars over two years.",[64],"Endodontically Treated Molar",[66,67,68],"overlay","endodontically treated molars","biomimetic preparation","NOT_YET_RECRUITING","2026-05-22",{"date":72,"type":73},"2026-05-29","ACTUAL",{"date":75,"type":58},"2026-06-15",{"date":77,"type":58},"2028-08-15",{"name":5,"class":6}]