[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100560119":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":8,"centralContacts":12,"locations":20,"responsibleParty":53,"collaborators":7,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":61,"eligibilityCriteria":62,"healthyVolunteers":57,"sex":63,"minAge":64,"maxAge":65,"enrollmentInfo":66,"targetDuration":7,"studyType":69,"phases":7,"briefSummary":70,"conditions":71,"keywords":7,"overallStatus":23,"whyStopped":7,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"University Hospital, Brest","OTHER",null,[9],{"name":10,"affiliation":5,"role":11},"Xavier Chapalain, MD","PRINCIPAL_INVESTIGATOR",[13,17],{"name":10,"role":14,"phone":15,"phoneExt":7,"email":16},"CONTACT","+33230337893","xavier.chapalain@chu-brest.fr",{"name":18,"role":14,"phone":7,"phoneExt":7,"email":19},"Dauphou Eddi","dauphou.eddi@chu-brest.fr",[21,38],{"facility":22,"status":23,"city":24,"state":7,"zip":25,"country":26,"countryCode":27,"cosmosGeoPoint":28,"geoPoint":33,"contacts":34},"Chu Brest","RECRUITING","Brest","29200","France","FR",{"type":29,"coordinates":30},"Point",[31,32],-4.48628,48.39029,{"lat":32,"lon":31},[35,37],{"name":36,"role":14,"phone":7,"phoneExt":7,"email":7},"Xavier CHAPALAIN",{"name":7,"role":14,"phone":7,"phoneExt":7,"email":16},{"facility":39,"status":40,"city":41,"state":7,"zip":42,"country":26,"countryCode":27,"cosmosGeoPoint":43,"geoPoint":47,"contacts":48},"Hegp - Aphp","NOT_YET_RECRUITING","Paris","75015",{"type":29,"coordinates":44},[45,46],2.3488,48.85341,{"lat":46,"lon":45},[49,51],{"name":50,"role":14,"phone":7,"phoneExt":7,"email":7},"Bernard Cholley",{"name":7,"role":14,"phone":7,"phoneExt":7,"email":52},"bernard.cholley@aphp.fr",{"type":54,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR","100560119","thoracic-fluid-content-during-stabilization-and-therapeutic-de-escalation-in-septic-shock-100560119",false,"NCT06572995","Thoracic Fluid Content During Stabilization and Therapeutic De-escalation in Septic Shock","Assessment of Intra-thoracic Water by Bio Reactance During Stabilization and Therapeutic De-escalation in Septic Shock: A Prospective, Multicenter, Observational Study","TFC-SEPSIS","Inclusion Criteria:\n\n* Adult (Age \\>18 years old)\n* Septic shock according to Sepsis-3 definition:\n\n  * A suspected or confirmed infection\n  * Persisting hypotension, despite adequate fluid resuscitation, requiring vasopressor to maintain a Mean Arterial Pressure (MAP) ≥ 65 mmHg\n  * Lactate level \\> 2 mmol\u002Fl\n* Predictive ICU length of stay \\> 3 days\n\nExclusion Criteria:\n\n* Admission in ICU for more than 3 days\n* Refusal to participate\n* Moribund patients\n* Decision of therapeutic withdrawal\n* Curators","ALL","18 Years","99 Years",{"count":67,"type":68},50,"ESTIMATED","OBSERVATIONAL","In ICU, fluid challenge represents one of the cornerstones of hemodynamic care. However, fluid overload due to an excessive and\u002For inappropriate fluid administration could be associated with morbidity or mortality. Unfortunately, there is currently no continuous non-invasive devices to monitor fluid content at bedside. Bio reactance is a non-invasive, rapid and continuous technology developed in order to measure body fluid compartment. Monitoring devices functioning with such technology are promising to evaluate fluid overload in ICU.",[72,73,74,75],"Sepsis","Septic Shock","Hemodynamic Instability","Fluid Overload","2024-08-26",{"date":78,"type":79},"2024-08-27","ACTUAL",{"date":81,"type":79},"2023-06-01",{"date":83,"type":68},"2025-06-01",{"name":5,"class":6},2]