[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100625319":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":7,"centralContacts":8,"locations":14,"responsibleParty":26,"collaborators":7,"id":30,"slug":31,"hasResults":32,"nctId":33,"briefTitle":34,"officialTitle":35,"acronym":7,"eligibilityCriteria":36,"healthyVolunteers":37,"sex":38,"minAge":39,"maxAge":7,"enrollmentInfo":40,"targetDuration":43,"studyType":44,"phases":7,"briefSummary":45,"conditions":46,"keywords":48,"overallStatus":54,"whyStopped":7,"lastUpdateSubmitDate":55,"lastUpdatePostDateStruct":56,"startDateStruct":59,"completionDateStruct":61,"leadSponsor":63,"locationsCount":64},{"fullName":5,"class":6},"University of Malaga","OTHER",null,[9],{"name":10,"role":11,"phone":12,"phoneExt":7,"email":13},"CARMEN MENAYA FERNANDEZ, Doctoral Student","CONTACT","+34658424375","cmenayaf@uma.es",[15],{"facility":16,"status":7,"city":17,"state":7,"zip":7,"country":18,"countryCode":19,"cosmosGeoPoint":20,"geoPoint":25,"contacts":7},"Universidad de Málaga","Málaga","Spain","ES",{"type":21,"coordinates":22},"Point",[23,24],-4.42034,36.72016,{"lat":24,"lon":23},{"type":27,"investigatorFullName":28,"investigatorTitle":29,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"PRINCIPAL_INVESTIGATOR","carmen menaya fernandez","Principal Investigator","100625319","thumb-muscle-activation-during-first-dorsal-interosseous-exercise-in-thumb-base-osteoarthritis-100625319",false,"NCT07421089","Thumb Muscle Activation During First Dorsal Interosseous Exercise in Thumb Base Osteoarthritis","A Between-Group Comparison of First Dorsal Interosseous and Abductor Pollicis Longus Muscle Activation During First Dorsal Interosseous Exercise in Individuals With and Without Thumb Base Osteoarthritis","Inclusion criteria for the TMC OA group:\n\n\\- Clinical diagnosis of thumb TMC osteoarthritis.\n\nInclusion criteria for the healthy group:\n\n\\- Participants with no history of musculoskeletal or neurological disorders affecting the dominant hand were included.\n\nExclusion Criteria :\n\n* Presence of numbness, tingling, or other sensory disturbances\n* Cardiac pacemaker implantation\n* Upper limb entrapment neuropathy or cervical radiculopathy\n* History of neuromuscular disease, polyneuropathy, or plexopathy\n* Systemic diseases such as diabetes, hypothyroidism, or chronic liver or kidney disease\n* History of cancer, rheumatoid arthritis, active anticoagulation therapy, chemotherapy, or exposure to neurotoxins\n* Recent upper limb soft tissue or bone injury (trauma, fracture, or surgery of the arm or neck).",true,"ALL","18 Years",{"count":41,"type":42},60,"ESTIMATED","4 Months","OBSERVATIONAL","The aim of this study is to investigate whether there are differences in muscle activation of the First Dorsal Interosseous (FDI) and the Abductor Pollicis Longus (APL) between individuals with and without trapeziometacarpal osteoarthritis (TMC OA) of the thumb. The study also seeks to identify which exercises are most effective for activating these muscles, in order to inform rehabilitation strategies for patients.\n\nThe FDI has been defined as a key stabilizer of the thumb TMC joint. However, the literature reports various protocols for FDI activation and limited information on APL behavior during these exercises. OA TMC of the thumb can cause pain, decreased thumb strength, impaired hand function, and difficulty performing activities of daily living (ADLs). Appropriate rehabilitation is essential to maintain muscle function, limit joint degeneration, and improve hand performance; however, the exercises that optimally activate the FDI and APL muscles are not yet established.\n\nParticipants will perform a series of standardized exercises and functional tasks designed to activate the FDI and APL muscles. Exercises include FDI strengthening with elastic bands in different hand positions (palmar and ulnar support), as well as exercises with the thumb in greater abduction. Functional tasks simulating everyday activities (e.g., turning a key, picking up a coin, writing, squeezing a tube of toothpaste, and holding a glass of water) will also be performed. Muscle activity will be recorded using surface electromyography (sEMG) during all tasks.\n\nAdults aged 40 years and older, both men and women, with TMC osteoarthritis and healthy controls without osteoarthritis will be invited to participate.\n\nResearchers will measure the activation patterns of the FDI and APL muscles during the exercises and functional tasks. The study aims to identify exercises that optimally activate these muscles, providing evidence to guide the rehabilitation of patients with thumb base osteoarthritis.",[47],"Trapeziometacarpal Osteoarthritis",[49,50,51,52,53],"muscle activation","trapeziometacarpal osteoarthritis","first dorsal interosseous","abductor pollicis longus","surface electromyography","NOT_YET_RECRUITING","2026-02-16",{"date":57,"type":58},"2026-02-19","ACTUAL",{"date":60,"type":42},"2026-01-28",{"date":62,"type":42},"2026-08",{"name":5,"class":6},1]