[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100623034":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":33,"centralContacts":38,"locations":32,"responsibleParty":47,"collaborators":32,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":53,"sex":59,"minAge":60,"maxAge":61,"enrollmentInfo":62,"targetDuration":32,"studyType":65,"phases":66,"briefSummary":68,"conditions":69,"keywords":73,"overallStatus":78,"whyStopped":32,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":32},{"fullName":5,"class":6},"Minia University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"surgical implants will inserted immediately after teeth extraction with xenograft.","PLACEBO_COMPARATOR","immediat implant placement with bone graft hydrogel",[13],"Procedure: group 1 xenograft hydrogel",{"label":15,"type":16,"description":17,"interventionNames":18},"study group","ACTIVE_COMPARATOR","surgical placement of 22 implants will inserted immediately after teeth extraction, combined xenograft and TQ gel.",[19],"Procedure: immediat implant placement wit TQ and bone graft hydrogel placement around implant",[21,28],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","group 1 xenograft hydrogel","22 implants will inserted immediately after teeth extraction with xenograft.",[9],[27],"control group",{"type":22,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"immediat implant placement wit TQ and bone graft hydrogel placement around implant","22 implants will inserted immediately after teeth extraction, combined xenograft and TQ gel.",[15],null,[34],{"name":35,"affiliation":36,"role":37},"aya kamal","lecturer of periodontology Minia University","PRINCIPAL_INVESTIGATOR",[39,45],{"name":40,"role":41,"phone":42,"phoneExt":43,"email":44},"shaimaa Hamdy, lecturer of Periodontology","CONTACT","+201030576405","+201555035523","shimaa.3m.sh@gmail.com",{"name":46,"role":41,"phone":32,"phoneExt":32,"email":44},"Turky, doctor",{"type":48,"investigatorFullName":49,"investigatorTitle":50,"investigatorAffiliation":5,"oldNameTitle":32,"oldOrganization":32},"SPONSOR_INVESTIGATOR","shaimaa hamdy","lecturer of periodontology","100623034","thymoquinone-around-immediate-implant-100623034",false,"NCT07391384","Thymoquinone Around Immediate Implant","Evaluation of the Effect of Thymoquinone Hydrogel With Bone Graft in Comparison to Bone Graft Only Around Immediate Implant (Randomized Controlled Clinical Trials)","Thymoquinone","Inclusion Criteria:\n\n* 1- Patients ages more than 18 years old, Participants were chosen according to specific eligibility criteria, requiring them to be healthy individuals classified as ASA I by the American Society of Anesthesiologists.\n\n  2- Patients requiring extraction of posterior teeth with consequent immediate implant placement.\n\n  3- Indications for extraction included: non restorable teeth (posterior teeth), untreatable caries, endodontic failures, remaining roots, vertical fracture of the roots.\n\n  4- Natural teeth adjacent to the tooth to be extracted will required to have complete occlusal surfaces and be free from infections..\n\n  5\\. Patients will selected with a thick soft tissue phenotype and a minimum keratinized tissue width (KTW) of 2 mm.\n\nExclusion Criteria:\n\n* Pathologies or drugs that alter tissue integration with dental implants. 2- Head and neck radiation therapy. 3- Renal disease, bleeding disorders and anticoagulant therapy. 4- Pregnant females. 5- Patients with severe para-functional habits and unfavorable occlusion 6- Smokers. 7- Malaligned teeth and teeth with acute periapical pathosis.","ALL","20 Years","55 Years",{"count":63,"type":64},44,"ESTIMATED","INTERVENTIONAL",[67],"NA","use of Thymoquinone hydrogel with bone graft in comparison to bone graft only around immediate implant-this hydrogel fill the jumping zone in comparison to using hydrogel bone graft only to increase primary stability and enhance osseointegration",[70,71,72],"Immediate Dental Implant Placement","Jumping Gap","Primary Stability of the Implants",[74,75,76,77],"immediate implant","thymoquinone","hydrogel","bone graft","NOT_YET_RECRUITING","2026-01-29",{"date":81,"type":82},"2026-02-05","ACTUAL",{"date":84,"type":64},"2026-01-21",{"date":86,"type":64},"2026-04-11",{"name":49,"class":6}]