[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100623484":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":35,"locations":44,"responsibleParty":58,"collaborators":26,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":26,"eligibilityCriteria":66,"healthyVolunteers":62,"sex":67,"minAge":68,"maxAge":69,"enrollmentInfo":70,"targetDuration":26,"studyType":73,"phases":74,"briefSummary":76,"conditions":77,"keywords":79,"overallStatus":86,"whyStopped":26,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"Nanjing First Hospital, Nanjing Medical University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Superior Laryngeal Nerve Space Block Group (C Group)","ACTIVE_COMPARATOR","All patients received topical oral and pharyngeal anesthesia using 2.4% lidocaine spray. The pharyngeal surface was sprayed twice, with each spray lasting one second, and repeated after a 5-minute interval. Under ultrasound guidance, the needle was advanced step by step into the potential space between the relevant muscle groups and the thyrohyoid membrane. When the needle tip contacted the surface of the thyrohyoid membrane and slightly penetrated the submembranous tissue, negative aspiration was confirmed, and 2.5 mL of 2% lidocaine was injected into the space on each side. Subsequently, performing fiberoptic bronchoscope-guided subglottis and tracheal surface topical anesthesia using 5ml of 2% lidocaine. After completing surface anesthesia, performing fiberoptic bronchoscope-guided tracheal intubation.",[13],"Procedure: Ultrasound-guided bilateral Superior Laryngeal Nerve Space Block",{"label":15,"type":16,"description":17,"interventionNames":18},"Thyroid Cartilage Plane Block Group (T Group)","EXPERIMENTAL","All patients received topical oral and pharyngeal anesthesia using 2.4% lidocaine spray. The pharyngeal surface was sprayed twice, with each spray lasting one second, and repeated after a 5-minute interval. Ultrasound-guided bilateral Thyroid Cartilage Plane Block is performed using the thyroid cartilage as an anatomical landmark. 2.5ml of 2% lidocaine is injected on the surface of the thyroid cartilage each side. Subsequently, performing fiberoptic bronchoscope-guided subglottis and tracheal surface topical anesthesia using 2% lidocaine 5ml. After completing surface anesthesia, performing fiberoptic bronchoscope-guided tracheal intubation.",[19],"Procedure: Ultrasound-guided bilateral Thyroid Cartilage Plane Block",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","Ultrasound-guided bilateral Thyroid Cartilage Plane Block","Use a SonoSite high-frequency linear array transducer (5-13 MHz, SonoSite, USA). Placing the transducer parallel to the spine on one side of the neck, ensuring clear visualization of the thyroid cartilage under ultrasound. Using the out-of-plane technique to visualize the needle insertion path and tip. Once the needle tip contacts the cranial half of the thyroid cartilage, injecting 2.5ml of 2% lidocaine on the surface of the thyroid cartilage each side.",[15],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Ultrasound-guided bilateral Superior Laryngeal Nerve Space Block","Use a SonoSite high-frequency linear array transducer (5-13 MHz, SonoSite, USA). Placing the transducer parallel to the spine on one side of the neck, ensuring clear visualization of the superior laryngeal nerve space under ultrasound. Using the out-of-plane technique to visualize the needle insertion path and tip. 2% lidocaine 2.5ml was injected into the space between the thyrohyoid membrane and muscle groups above.",[9],[32],{"name":33,"affiliation":5,"role":34},"Tao Shan","PRINCIPAL_INVESTIGATOR",[36,40],{"name":33,"role":37,"phone":38,"phoneExt":26,"email":39},"CONTACT","+8618852095135","858727933@qq.com",{"name":41,"role":37,"phone":42,"phoneExt":26,"email":43},"Ying Zhang","+8615380998716","1070434273@qq.com",[45],{"facility":46,"status":26,"city":47,"state":48,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":26},"Nanjing First Hospital","Nanjing","Jiangsu","210006","China","CN",{"type":53,"coordinates":54},"Point",[55,56],118.77778,32.06167,{"lat":56,"lon":55},{"type":34,"investigatorFullName":33,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Attending physician","100623484","thyroid-cartilage-plane-vs-superior-laryngeal-nerve-space-block-in-awake-tracheal-intubation-100623484",false,"NCT07397234","Thyroid Cartilage Plane VS Superior Laryngeal Nerve Space Block in Awake Tracheal Intubation","Thyroid Cartilage Plane Versus Superior Laryngeal Nerve Space for Ultrasound-guided Superior Laryngeal Nerve Block in Awake Tracheal Intubation: a Randomised Non-inferiority Clinical Trial","Inclusion Criteria:\n\n1. Patients scheduled for awake tracheal intubation under general anesthesia.\n2. Patients with difficult airways (e.g., limited cervical spine mobility, full stomach, partial airway obstruction, craniofacial deformities or trauma, micrognathia, mouth opening \\\u003C3cm, Mallampati III or IV classification) posing challenges for mask ventilation or intubation.\n3. Age between 18 and 85 years old.\n4. Gender is not restricted.\n5. ASA classification of I - III.\n\nExclusion Criteria:\n\n1. Cardiovascular dysfunction or arterial aneurysms.\n2. Mental or neurological disorders or concomitant arterial aneurysms.\n3. Infection at the puncture site.\n4. Allergy to local anesthetics.\n5. Continuous use of antiplatelet or anticoagulant medications preoperatively.\n6. Hoarseness or coughing while drinking water.\n7. Bronchial asthma.\n8. Participation in other clinical trials within the previous 3 months before enrollment 9.r current participation in other clinical trials.","ALL","18 Years","85 Years",{"count":71,"type":72},94,"ESTIMATED","INTERVENTIONAL",[75],"NA","The aim of this clinical trial is to compare the effectiveness and safety of ultrasound-guided thyroid cartilage plane approach with the superior laryngeal nerve space approach for superior laryngeal nerve block in awake tracheal intubation. Patients were randomized into the thyroid cartilage plane block group (T group) or the superior laryngeal nerve space block group (C group). In Group T, bilateral thyroid cartilage plane block was performed under ultrasound with thyroid cartilage as the landmark, and local anesthetic was injected on the surface of the thyroid cartilage. In Group C, local anesthetic was injected into the space between the thyrohyoid membrane and muscle groups above.\n\nWe aim to evaluate whether the thyroid cartilage plane approach is not inferior to the superior laryngeal nerve space approach for ultrasound-guided superior laryngeal nerve block in awake tracheal intubation",[78],"Superior Laryngeal Nerve Block",[80,81,82,83,84,85],"Thyroid Cartilage plane","Superior laryngeal nerve space","Difficult airway","Superior Laryngeal Nerve","Awake tracheal intubation","Nerve block","NOT_YET_RECRUITING","2026-02-02",{"date":89,"type":90},"2026-02-09","ACTUAL",{"date":92,"type":72},"2026-03-02",{"date":94,"type":72},"2027-09-01",{"name":5,"class":6},1]