[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100613870":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":20,"locations":29,"responsibleParty":46,"collaborators":10,"id":49,"slug":50,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":57,"sex":58,"minAge":59,"maxAge":60,"enrollmentInfo":61,"targetDuration":64,"studyType":65,"phases":10,"briefSummary":66,"conditions":67,"keywords":72,"overallStatus":31,"whyStopped":10,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"Gaziosmanpasa Research and Education Hospital","OTHER_GOV",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"TSH ≤2.5 Group",null,"Participants in this cohort have serum TSH levels ≤2.5 mIU\u002FL. No intervention will be administered. Participants will undergo psychometric evaluation using the Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), the Arizona Sexual Experience Scale (ASEX), and the YKK-13 Quality of Life Scale. The purpose is to assess psychological and sexual function outcomes in relation to normal-range TSH levels.",{"label":13,"type":10,"description":14,"interventionNames":10},"TSH >2.5 Group","Participants in this cohort have serum TSH levels \\>2.5 mIU\u002FL. No intervention will be administered. Participants will complete the same psychometric assessments (BDI, BAI, ASEX, YKK-13). This group will allow comparison of psychological, anxiety-related, sexual function, and quality-of-life outcomes associated with elevated TSH levels during pregnancy.",[16],{"name":17,"affiliation":18,"role":19},"havva betül bacak, md","SBÜ Gaziosmanpaşa Training and Research Hospital","PRINCIPAL_INVESTIGATOR",[21,25],{"name":17,"role":22,"phone":23,"phoneExt":10,"email":24},"CONTACT","+905333610088","hbbacak90@gmail.com",{"name":26,"role":22,"phone":27,"phoneExt":10,"email":28},"fatih irice, md","5055434973","fatihirice@gmai.com",[30],{"facility":18,"status":31,"city":32,"state":33,"zip":34,"country":35,"countryCode":10,"cosmosGeoPoint":36,"geoPoint":41,"contacts":42},"RECRUITING","Istanbul","Gaziosmanpaşa","33400","Turkey (Türkiye)",{"type":37,"coordinates":38},"Point",[39,40],28.94966,41.01384,{"lat":40,"lon":39},[43,44],{"name":17,"role":22,"phone":23,"phoneExt":10,"email":24},{"name":26,"role":22,"phone":27,"phoneExt":10,"email":45},"fatihirice@gmail.com",{"type":19,"investigatorFullName":47,"investigatorTitle":48,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Havva Betül Bacak","Specialist in Obstetrics and Gynecology","100613870","thyroid-stimulating-hormone-levels-in-pregnancy-and-their-association-with-depression-anxiety-and-sexual-function-100613870",false,"NCT07272213","Thyroid-Stimulating Hormone Levels in Pregnancy and Their Association With Depression, Anxiety, and Sexual Function","Evaluation of the Effects of Thyroid-Stimulating Hormone (TSH) Levels in Pregnancy on Depression, Anxiety, and Sexual Function","TSH-MIND","Inclusion Criteria:\n\nPregnant women aged 18-45 years\n\nSingleton pregnancy\n\nGestational age ≥ 6 weeks\n\nLiteracy and ability to provide informed consent\n\nAvailability of a TSH result obtained within the past 4 weeks\n\nCognitive ability sufficient to complete the psychometric questionnaires (Beck Depression Inventory, Beck Anxiety Inventory, ASEX, and YKK-13 Quality of Life Scale)\n\nExclusion Criteria:\n\nMultiple pregnancy\n\nPreviously diagnosed psychiatric disorder or active use of antidepressant\u002F anxiolytic medication\n\nCurrent treatment for thyroid disease\n\nHistory of thyroid surgery\n\nMajor systemic illness or significant obstetric complications\n\nAge under 18 years or inability to provide informed consent\n\nInability to complete the questionnaires adequately (missing or invalid data)\n\nRationale:\n\nMultiple pregnancies are excluded because they differ significantly from singleton pregnancies in terms of hormonal profile, obstetric risks, and psychological stress levels. This exclusion aims to ensure a homogeneous study population.",true,"FEMALE","18 Years","45 Years",{"count":62,"type":63},180,"ESTIMATED","1 Month","OBSERVATIONAL","This prospective, single-center, observational cross-sectional study aims to evaluate the relationship between thyroid-stimulating hormone (TSH) levels and psychological as well as sexual health outcomes during pregnancy. Pregnant individuals will undergo psychometric assessment using the Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), the Arizona Sexual Experience Scale (ASEX), and the YKK-13 Quality of Life Scale. The study will investigate whether maternal TSH levels are associated with depression, anxiety, sexual function, and overall quality of life scores.\n\nEligible participants will be pregnant women aged 18-45 years with a singleton pregnancy of at least 6 weeks, who are literate and have provided informed consent. Individuals with a prior psychiatric history, multiple gestation, or existing systemic or endocrine diseases will be excluded. The primary endpoint of the study is to determine the association between TSH levels and psychometric scale scores during pregnancy.",[68,69,70,71],"Thyroid Disorders Complicating Pregnancy","Maternal Depression in Pregnancy, Unspecified Trimester","Anxiety Disorder, Unspecified","Sexual Dysfunction, Unspecified",[73,74,75,76],"Thyroid disorders complicating pregnancy","Maternal depression in pregnancy, unspecified trimester","Anxiety disorder, unspecified","Sexual dysfunction, unspecified","2025-11-26",{"date":79,"type":80},"2025-12-09","ACTUAL",{"date":82,"type":80},"2025-11-01",{"date":84,"type":63},"2025-12-01",{"name":5,"class":6},1]