[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100595754":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":18,"centralContacts":24,"locations":34,"responsibleParty":57,"collaborators":18,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":65,"eligibilityCriteria":66,"healthyVolunteers":61,"sex":67,"minAge":68,"maxAge":69,"enrollmentInfo":70,"targetDuration":18,"studyType":73,"phases":74,"briefSummary":76,"conditions":77,"keywords":79,"overallStatus":37,"whyStopped":18,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"Norwegian University of Science and Technology","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Time-restricted eating and high-intensity interval training","EXPERIMENTAL","12 months of periodised time-restricted eating and high-intensity interval training with digital follow-up",[13],"Behavioral: Time-restricted eating and high-intensity interval training",{"label":15,"type":16,"description":17,"interventionNames":18},"Control","NO_INTERVENTION","No intervention or follow-up. Habitual lifestyle",null,[20],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":18},"BEHAVIORAL","1-month intense periods of maximal daily eating window of 10 hours and high-intensity interval training (three weekly, unsupervised, aerobic exercise sessions performed at \\> 90 % heart rate maximum), separated by 3-month maintenance periods of time-restricted eating on 5 days per week and minimum 1 HIIT session per week. Each exercise session will last for 33-38 minutes. Participants will receive digital follow-up once weekly during intense periods, and once monthly during maintenance periods. The intervention period will be 12 months in total.",[9],[25,30],{"name":26,"role":27,"phone":28,"phoneExt":18,"email":29},"Kamilla La Haganes, PhD","CONTACT","+4747316765","kamilla.l.haganes@ntnu.no",{"name":31,"role":27,"phone":32,"phoneExt":18,"email":33},"Trine Moholdt, PhD","+4797098594","trine.moholdt@ntnu.no",[35],{"facility":36,"status":37,"city":38,"state":18,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"Department of circulation and medical imaging, NTNU","RECRUITING","Trondheim","7491","Norway","NO",{"type":43,"coordinates":44},"Point",[45,46],10.39506,63.43049,{"lat":46,"lon":45},[49,53,55],{"name":50,"role":27,"phone":51,"phoneExt":18,"email":52},"Beathe Sitter, PhD","+47 73412318","beathe.sitter@ntnu.no",{"name":26,"role":54,"phone":18,"phoneExt":18,"email":18},"SUB_INVESTIGATOR",{"name":31,"role":56,"phone":18,"phoneExt":18,"email":18},"PRINCIPAL_INVESTIGATOR",{"type":58,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR","100595754","time-restricted-eating-and-high-intensity-interval-training-for-metabolic-health-in-adults-with-overweightobesity-100595754",false,"NCT07036562","Time-restricted Eating and High-intensity Interval Training for Metabolic Health in Adults With Overweight\u002FObesity","Time-restricted Eating and High-intensity Interval Training for Long-term Improvement in Metabolic Health","TREHIIT-3","Inclusion Criteria:\n\n* Body mass index ≥ 27 kg\u002Fm²\n* Able to walk or ride a bike \\> 60 min\n\nExclusion Criteria:\n\n* On-going pregnancy\n* Lactation within 24 weeks of study commencement\n* High-intensity exercise ≥ 1\u002Fweek\n* Habitual eating window ≤12 hours\u002Fday\n* Taking hypertension, glucose-, or lipid-lowering drugs\n* Body mass variation ≥ 4 kg three months prior to study commencement\n* Known diabetes mellitus (type 1 or 2) or cardiovascular disease\n* Working night shifts","ALL","18 Years","50 Years",{"count":71,"type":72},100,"ESTIMATED","INTERVENTIONAL",[75],"NA","This study will investigate the effects of 12 months periodised time-restricted eating combined with high-intensity interval training compared with a control group on fat mass in adults with overweight\u002Fobesity. Participants in the intervention group will complete the intervention remotely and will receive follow-up by telephone. Before randomisation, after 6 months and after 12 months, the investigators will measure the participants' body composition, physical fitness, fasting blood glucose and insulin, blood lipids, and blood pressure. Physical activity, diet, sleep quality, appetite, and adherence to the intervention will also be measured. Secondary sub-analyses of sex differences in the responses to the intervention will be performed.",[78],"Overweight and Obesity",[80,81,82,83,84,85],"time-restricted eating","high-intensity interval training","exercise","diet","metabolic health","lifestyle intervention","2025-12-05",{"date":88,"type":89},"2025-12-12","ACTUAL",{"date":91,"type":89},"2025-09-11",{"date":93,"type":72},"2027-07",{"name":5,"class":6},1]