[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100617133":3},{"organization":4,"armGroups":7,"interventions":28,"overallOfficials":27,"centralContacts":42,"locations":51,"responsibleParty":69,"collaborators":27,"id":71,"slug":72,"hasResults":73,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":27,"eligibilityCriteria":77,"healthyVolunteers":78,"sex":79,"minAge":80,"maxAge":27,"enrollmentInfo":81,"targetDuration":27,"studyType":84,"phases":85,"briefSummary":87,"conditions":88,"keywords":27,"overallStatus":53,"whyStopped":27,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":99},{"fullName":5,"class":6},"University of Surrey","OTHER",[8,14,19,24],{"label":9,"type":10,"description":11,"interventionNames":12},"TRE","EXPERIMENTAL","Participants undertaking the TRE intervention",[13],"Other: TRE",{"label":15,"type":10,"description":16,"interventionNames":17},"ProtAM TRE","Participants undertaking the ProtAM TRE intervention",[18],"Other: ProtAM TRE",{"label":20,"type":10,"description":21,"interventionNames":22},"ProtPM TRE","Participants undertaking the ProtPM TRE intervention",[23],"Other: ProtPM TRE",{"label":25,"type":26,"description":27,"interventionNames":27},"Control","NO_INTERVENTION",null,[29,32,37],{"type":6,"name":9,"description":30,"armGroupLabels":31,"otherNames":27},"* Participants will be asked to follow a 16:8 TRE protocol, consuming all their daily within 8 hours, between 12 and 8pm, and fast for 16 hours overnight.\n* Outside of the eating window, participants will be allowed to consume energy-free drinks only, i.e. water, black tea\u002Fcoffee, 0-calorie soft drinks.",[9],{"type":6,"name":15,"description":33,"armGroupLabels":34,"otherNames":35},"* Participants will be asked to follow a 16:8 TRE protocol, consuming all their daily within 8 hours, between 12 and 8pm, and fast for 16 hours overnight.\n* Outside of the eating window, participants will be allowed to consume energy-free drinks only, i.e. water, black tea\u002Fcoffee, 0-calorie soft drinks.\n* In addition, they will be asked to consume a protein drink containing 30g protein in the morning, 2 hours before the 8-hour eating window opens at 12pm (i.e. at 10am).",[15],[36],"TRE + morning protein 'snack'",{"type":6,"name":20,"description":38,"armGroupLabels":39,"otherNames":40},"* Participants will be asked to follow a 16:8 TRE protocol, consuming all their daily within 8 hours, between 12 and 8pm, and fast for 16 hours overnight.\n* Outside of the eating window, participants will be allowed to consume energy-free drinks only, i.e. water, black tea\u002Fcoffee, 0-calorie soft drinks.\n* In addition, they will be asked to consume a protein drink containing 30g protein in the afternoon, either 2 hours after their first meal or 2 hours before their last meal of the day.",[20],[41],"TRE + afternoon protein 'snack'",[43,48],{"name":44,"role":45,"phone":46,"phoneExt":27,"email":47},"Yana Petkova","CONTACT","+44 7513 679 635","yp00228@surrey.ac.uk",{"name":49,"role":45,"phone":27,"phoneExt":27,"email":50},"Dr Collins","a.collins@surrey.ac.uk",[52],{"facility":5,"status":53,"city":54,"state":27,"zip":55,"country":56,"countryCode":57,"cosmosGeoPoint":58,"geoPoint":63,"contacts":64},"RECRUITING","Guildford","GU2 7XH","United Kingdom","UK",{"type":59,"coordinates":60},"Point",[61,62],-0.57427,51.23536,{"lat":62,"lon":61},[65,66,67],{"name":44,"role":45,"phone":46,"phoneExt":27,"email":47},{"name":49,"role":45,"phone":27,"phoneExt":27,"email":50},{"name":49,"role":68,"phone":27,"phoneExt":27,"email":27},"PRINCIPAL_INVESTIGATOR",{"type":70,"investigatorFullName":27,"investigatorTitle":27,"investigatorAffiliation":27,"oldNameTitle":27,"oldOrganization":27},"SPONSOR","100617133","time-restricted-eating-tre-and-protein-in-older-adults-100617133",false,"NCT07314658","Time-restricted Eating (TRE) and Protein in Older Adults","The Effects of Time-restricted Eating (TRE) With and Without Additional Protein on Body Composition, Muscle Function and Markers of Metabolic Health in Older Adults","Inclusion Criteria:\n\n* Gender: male and female\n* Age range: 60 years or older\n* Fasting for 12 or less hours on a daily basis\n* BMI range: 23-30 kg\u002Fm2\n* Weight stability: no more than 3kg weight gain or loss in the past 3 months\n* Regular eating pattern, i.e. 3 meals a day\n* Able to prepare the protein supplement\n\nExclusion Criteria:\n\n* Any of the following present (in line with exclusion criteria used in previous TRE research in older adults):\n\n  * known renal impairment\n  * heart attack or stroke in the past three months\n  * continuous use of supplemental oxygen to manage a chronic pulmonary condition or heart failure\n  * rheumatoid arthritis\n  * Parkinson's disease\n  * active treatment for cancer in the past year\n  * insulin dependent diabetes mellitus\n* taking medications that preclude fasting for 16 h\n* actively trying or planning to lose weight\n* history of an eating disorder\n* outside of stated age or BMI range\n* fasting for longer than 12 hours on a daily basis\n* unable to prepare the protein supplement\n* extreme morning\u002Fevening chronotype\n* sleep disorders\n* regular meal skipping\n* history of difficulty having a blood sample taken\n* Recent exposure to high-dose radiation\n* Vigorous exercise on more than 3 occasions a week",true,"ALL","60 Years",{"count":82,"type":83},80,"ESTIMATED","INTERVENTIONAL",[86],"NA","The aim this study is to investigate the effects of time-restricted eating (TRE) on body composition, muscle function and markers of metabolic health of adults over 60 years old. This study will compare different variations of TRE - with and without an additional protein.\n\nThis study involves attending two study days at the University of Surrey for baseline and end-of-intervention measurement of body composition using a gold-standard dual energy x-ray absorptiometry (DEXA) scan; muscle function using hand grip strength and 30-second sit-to-stand tests; weight. A blood sample will be taken at each study visit to measure markers of lipid and glucose control, and insulin sensitivity.\n\nParticipants will be randomly allocated to one of four study groups:\n\n* control group: maintain habitual dietary patterns\n* TRE group: fast for 16 hours overnight, eat between 12-8pm\n* TRE + Protein (AM): fast for 16 hours overnight, eat between 12-8pm; take a 30g plant-based protein supplement in the morning\n* TRE + Protein (PM): fast for 16 hours overnight, eat between 12-8pm; take a 30g plant-based protein supplement in the afternoon Participants will be asked to follow the intervention according to their allocated group for 8 weeks.",[89],"Generally Healthy Adults Over 60 Years Old","2025-12-17",{"date":92,"type":93},"2026-01-02","ACTUAL",{"date":95,"type":83},"2025-12",{"date":97,"type":83},"2027-07",{"name":5,"class":6},1]