[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100435380":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":31,"centralContacts":40,"locations":46,"responsibleParty":64,"collaborators":31,"id":68,"slug":69,"hasResults":70,"nctId":71,"briefTitle":72,"officialTitle":73,"acronym":74,"eligibilityCriteria":75,"healthyVolunteers":76,"sex":77,"minAge":78,"maxAge":79,"enrollmentInfo":80,"targetDuration":31,"studyType":83,"phases":84,"briefSummary":86,"conditions":87,"keywords":31,"overallStatus":49,"whyStopped":31,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":99},{"fullName":5,"class":6},"University of Arkansas, Fayetteville","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"TRF-C","PLACEBO_COMPARATOR","Follows time restricted feeding protocol.",[13],"Other: Control group - time restricted feeding only",{"label":15,"type":16,"description":17,"interventionNames":18},"TRF-P","EXPERIMENTAL","Follows time restricted feeding protocol, consumes protein supplement",[19],"Dietary Supplement: Whey protein supplement",{"label":21,"type":16,"description":22,"interventionNames":23},"TRF-S","Follows time restricted feeding protocol, consumes ketogenic supplement",[24],"Dietary Supplement: Ketogenic aid",[26,32,36],{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"DIETARY_SUPPLEMENT","Whey protein supplement","Participants consume whey protein at the beginning of the eating period.",[15],null,{"type":27,"name":33,"description":34,"armGroupLabels":35,"otherNames":31},"Ketogenic aid","Participants consume ketogenic aid upon waking.",[21],{"type":6,"name":37,"description":38,"armGroupLabels":39,"otherNames":31},"Control group - time restricted feeding only","Time restricted feeding.",[9],[41],{"name":42,"role":43,"phone":44,"phoneExt":31,"email":45},"Jamie Baum, PhD","CONTACT","479-575-4474","baum@uark.edu",[47],{"facility":48,"status":49,"city":50,"state":51,"zip":52,"country":53,"countryCode":54,"cosmosGeoPoint":55,"geoPoint":60,"contacts":61},"University of Arkansas","RECRUITING","Fayetteville","Arkansas","72704","United States","US",{"type":56,"coordinates":57},"Point",[58,59],-94.15743,36.06258,{"lat":59,"lon":58},[62],{"name":63,"role":43,"phone":44,"phoneExt":31,"email":45},"Jamie I Baum, PhD",{"type":65,"investigatorFullName":66,"investigatorTitle":67,"investigatorAffiliation":5,"oldNameTitle":31,"oldOrganization":31},"PRINCIPAL_INVESTIGATOR","Jamie Baum","Associate Professor","100435380","time-restricted-feeding-muscle-and-metabolism-100435380",false,"NCT04949451","Time Restricted Feeding, Muscle, and Metabolism","Time Restricted Feeding Intervention for Muscle and Metabolic Health (TRIMM)","TRIMM","Inclusion Criteria:\n\n* Resides in Northwest Arkansas\n* Age 25-50 years\n* BMI \\> 25\n* All ethnicities\n* Female and male\n\nExclusion Criteria:\n\n* Food allergies\n* Pregnant or breastfeeding\n* Dietary restrictions (e.g. vegetarian, vegan, etc.)\n* Trying to lose weight in last 3 months\n* Pre-existing health conditions related to obesity (e.g. cardiovascular disease, diabetes, hypertension)\n* Prescription medications related to heart disease or type 2 diabetes\n* Fear of needles\n* Smoker or vaping\n* Currently taking protein supplements or other nutritional supplements which may interfere with study outcomes\n* Consumes \\>4 alcoholic beverages per week",true,"ALL","25 Years","50 Years",{"count":81,"type":82},90,"ESTIMATED","INTERVENTIONAL",[85],"NA","Effective nutrition strategies for combatting and\u002For preventing obesity still need to be identified. This has been the case despite the numerous and different approaches that have been taken. Potential targets for combatting\u002Fpreventing obesity have been identified, but long-term solutions have not emerged. This study uses time restricted feeding to study the role of dietary protein in obesity prevention and\u002For treatment. The objectives are to determine the role of skeletal muscle mass as a driver of energy-sensing mechanisms and peripheral signals that regulate appetite and energy intake in overweight and obese adults and to determine the effects of protein timing on muscle mass to regulate appetite and energy intake in overweight and obese adults.",[88,89],"Overweight","Obesity","2025-08-19",{"date":92,"type":93},"2025-08-26","ACTUAL",{"date":95,"type":93},"2021-06-13",{"date":97,"type":82},"2025-12-30",{"name":5,"class":6},1]