[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100524798":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":26,"centralContacts":30,"locations":36,"responsibleParty":56,"collaborators":59,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":68,"eligibilityCriteria":69,"healthyVolunteers":64,"sex":70,"minAge":71,"maxAge":25,"enrollmentInfo":72,"targetDuration":25,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":82,"overallStatus":39,"whyStopped":25,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"Hospital Universitario Mayor Méderi","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Early cholecystectomy","EXPERIMENTAL","Early laparoscopic cholecystectomy (within 72 hours after randomization)",[13],"Procedure: Laparoscopic cholecystectomy",{"label":15,"type":16,"description":17,"interventionNames":18},"Interval cholecystectomy","ACTIVE_COMPARATOR","Interval laparoscopic cholecystectomy (30 +\u002F- 5 days after randomization).",[13],[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Laparoscopic cholecystectomy","Laparoscopic cholecystectomy will be performed using the standard American 4-port technique, insufflation will be achieved using CO2 to 15mmHg of pressure. Calot's triangle will be dissected until the critical view of safety is reached, being careful to dissect above the R4U line. After reaching the critical view of safety, two proximal and one distal clip will be placed on both the cystic conduct and artery separately, cutting the clips and then dissecting the gallbladder in a cystfundic direction. When the critical view of safety is not reached, the surgeon may perform a fundus-first cholecystectomy, subtotal cholecystectomy, conversion to open procedure, intraoperative cholangiography or cholecystostomy to their own discretion. It will also be the surgeon's criteria to employ or not a drain system in the surgical site. The decision for theses interventions will be taken intraoperatively and will be according to findings during the procedure.",[9,15],null,[27],{"name":28,"affiliation":5,"role":29},"Camilo Ramirez-Giraldo, MD","PRINCIPAL_INVESTIGATOR",[31],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},"Camilo Ramírez-Giraldo, MD","CONTACT","+5773206770474","ramirezgiraldocamilo@gmail.com",[37,49],{"facility":38,"status":39,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":25,"geoPoint":25,"contacts":45},"Hospital Universitario Mayor-Méderi","RECRUITING","Bogota","Cundinamarca","111221","Colombia","CO",[46],{"name":47,"role":33,"phone":48,"phoneExt":25,"email":35},"Camilo Ramírez-Giraldo","57 3206770474",{"facility":50,"status":39,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":25,"geoPoint":25,"contacts":51},"Hospital Universitario Méderi Barrios Unidos",[52],{"name":53,"role":33,"phone":54,"phoneExt":25,"email":55},"Isabella Van","3206955392","isabellavanl@gmail.com",{"type":29,"investigatorFullName":57,"investigatorTitle":58,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Camilo Ramirez Giraldo","General Surgeon",[60],{"name":61,"class":6},"Universidad del Rosario","100524798","timing-of-cholecystectomy-in-severe-pancreatitis-100524798",false,"NCT06113419","Timing of CHolecystectomy In Severe PAncreatitis","Timing of CHolecystectomy In Severe PAncreatitis (CHISPA): Study Protocol for a Randomized Controlled Trial.","CHISPA","Inclusion Criteria:\n\n* Age ≥18 years, diagnosis of pancreatitis according to Atlanta guidelines, moderately severe or severe pancreatitis (APACHE score ≥8 on admittance)\n* Biliary pancreatitis diagnosed on imaging (be it ultrasound, magnetic resonance imaging and\u002For tomography)\n* Recovery of pancreatitis by tolerance of oral intake (defined as 24 hours of food consumption of any consistency without emetic episodes and pain defined as 4\u002F10 on the visual analogue score of pain) and written informed consent.\n\nExclusion Criteria:\n\n* Pregnancy\n* History of cholecystectomy\n* Planned open cholecystectomy\n* Pancreatitis-associated complication before laparoscopic cholecystectomy (compartment syndrome, bleeding and\u002For need for peripancreatic collection drainage)\n* Chronic pancreatitis,\n* More than one episode of pancreatitis\n* Active malignant disease\n* Septic shock\n* Choledocholithiasis not resolved by ERCP, post-ERCP perforation and post-ERCP concomitant pancreatitis.","ALL","18 Years",{"count":73,"type":74},134,"ESTIMATED","INTERVENTIONAL",[77],"NA","The goal of this clinical trial is to compare outcomes for interval or early laparoscopic cholecystectomy in patients with moderately severe and severe pancreatitis. The main question\\[s\\] it aims to answer are:\n\n* To establish whether there is a difference in surgical outcomes comparing patients diagnosed with severe or moderately severe pancreatitis on which early cholecystectomy was performed versus performing interval cholecystectomy.\n* The primary endpoint will be to evaluate major complications, defined as a Clavien-Dindo score greater than or equal to III\u002FV.\n* Secondary endpoints include evaluating minor complications (defined as a Clavien-Dindo score below III\u002FV), biliary disease recurrence, mortality, postoperative hospital stay and postoperative admittance into an intensive care unit.\n\nParticipants will be randomly assigned to either group: early cholecystectomy during the pancreatitis hospitalization or interval cholecystectomy scheduled 4 weeks after clinical resolution of pancreatitis.",[80,81],"Acute Pancreatitis","Cholelithiasis",[83,80,81],"cholecystectomy","2025-09-09",{"date":86,"type":87},"2025-09-15","ACTUAL",{"date":89,"type":87},"2024-04-01",{"date":91,"type":74},"2027-06",{"name":5,"class":6},2]