[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100586654":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":24,"centralContacts":25,"locations":32,"responsibleParty":48,"collaborators":24,"id":50,"slug":51,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":56,"eligibilityCriteria":57,"healthyVolunteers":52,"sex":58,"minAge":59,"maxAge":60,"enrollmentInfo":61,"targetDuration":24,"studyType":64,"phases":65,"briefSummary":67,"conditions":68,"keywords":24,"overallStatus":35,"whyStopped":24,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":79},{"fullName":5,"class":6},"Al Hayah University In Cairo","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Early Initiation of Specific Exercise Therapy","EXPERIMENTAL","In this group, participants will initiate specific exercise therapy within the first postoperative week. They will receive 40-minute supervised sessions twice weekly for 8 weeks, with a transition to a prescribed home-based maintenance program for an additional 4 months.",[13],"Behavioral: Specific Exercise Therapy",{"label":15,"type":10,"description":16,"interventionNames":17},"Delayed Initiation of Specific Exercise Therapy","Participants in this group will begin the same specific exercise therapy protocol at 3 weeks postoperative. Otherwise, the intervention is identical to that provided to the Early Therapy group.",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"BEHAVIORAL","Specific Exercise Therapy","The exercise protocol includes mobilisation and stretching with 40-minute sessions twice weekly for 8 weeks post-initiation, transitioning to a home-based maintenance phase for 4 months. All sessions will be supervised by certified physiotherapists.",[15,9],null,[26],{"name":27,"role":28,"phone":29,"phoneExt":30,"email":31},"Mohamed ElMeligie, Ph.D","CONTACT","01159880001","+20","mohamed.elmeligie@ahuc.edu.eg",[33],{"facility":34,"status":35,"city":36,"state":24,"zip":37,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"Faculty of Physical Therapy, Al Hayah University","RECRUITING","Cairo","12311","Egypt","EG",{"type":41,"coordinates":42},"Point",[43,44],31.24967,30.06263,{"lat":44,"lon":43},[47],{"name":27,"role":28,"phone":29,"phoneExt":30,"email":31},{"type":49,"investigatorFullName":24,"investigatorTitle":24,"investigatorAffiliation":24,"oldNameTitle":24,"oldOrganization":24},"SPONSOR","100586654","timing-of-specific-exercise-therapy-after-breast-cancer-surgery-early-versus-delayed-initiation-100586654",false,"NCT06918184","Timing of Specific Exercise Therapy After Breast Cancer Surgery: Early Versus Delayed Initiation","Timing of Specific Exercise Therapy After Breast Cancer Surgery: A Single-Center, Parallel-Group Randomized Controlled Trial Comparing Early (\u003C1 Week Postoperative) Versus Delayed (3 Weeks Postoperative) Initiation for Optimized Upper Limb Function","BEST-Timing","Inclusion Criteria:\n\n* Women aged 18-65 years.\n* Scheduled to undergo breast cancer surgery with axillary node dissection.\n* At risk for upper limb morbidity based on preoperative assessment.\n* Able to provide informed consent and complete study questionnaires.\n* Willing and able to attend scheduled physiotherapy sessions and follow-up evaluations.\n\nExclusion Criteria:\n\n* Diagnosis of recurrent or metastatic breast cancer.\n* Concurrent participation in another rehabilitation intervention or clinical trial.\n* Severe comorbidities (e.g., uncontrolled cardiovascular disease, severe orthopedic conditions) that preclude safe participation.\n* History of previous shoulder surgery or chronic upper extremity musculoskeletal disorders unrelated to breast cancer treatment.\n* Inability to understand or complete study materials in English.\n* Pregnancy or lactation.","ALL","18 Years","65 Years",{"count":62,"type":63},140,"ESTIMATED","INTERVENTIONAL",[66],"NA","This single-center, parallel-group randomized controlled trial (RCT) will compare two timings for initiating specific exercise therapy after breast cancer surgery. The study tests whether early initiation (within the first postoperative week) versus delayed initiation (at 3 weeks postoperative) results in superior upper limb function at 6 months as measured by the Disabilities of the Arm, Shoulder, and Hand (DASH) questionnaire. Secondary outcomes include pain intensity (Visual Analog Scale, VAS) and wound-related complications such as drainage time and hematoma incidence.",[69],"Breast Cancer","2025-04-05",{"date":72,"type":73},"2025-04-09","ACTUAL",{"date":75,"type":63},"2025-04-15",{"date":77,"type":63},"2026-11-15",{"name":5,"class":6},1]