[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100626846":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":25,"centralContacts":30,"locations":39,"responsibleParty":55,"collaborators":24,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":24,"eligibilityCriteria":63,"healthyVolunteers":59,"sex":64,"minAge":65,"maxAge":66,"enrollmentInfo":67,"targetDuration":24,"studyType":70,"phases":71,"briefSummary":73,"conditions":74,"keywords":77,"overallStatus":42,"whyStopped":24,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"Eulji University Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Pre-incisional Block Group","EXPERIMENTAL","Participants receive ultrasound-guided subcostal transversus abdominis plane (TAP) block combined with rectus sheath block (RSB) after induction of general anesthesia and before surgical incision.",[13],"Procedure: Ultrasound-guided subcostal TAP block combined with rectus sheath block",{"label":15,"type":10,"description":16,"interventionNames":17},"Postoperative Block Group","Participants receive ultrasound-guided subcostal transversus abdominis plane (TAP) block combined with rectus sheath block (RSB) after completion of surgery and before emergence from anesthesia.",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"PROCEDURE","Ultrasound-guided subcostal TAP block combined with rectus sheath block","Ultrasound-guided right subcostal transversus abdominis plane (TAP) block combined with bilateral rectus sheath block (RSB) is performed under sterile conditions using local anesthetic for postoperative analgesia.",[15,9],null,[26],{"name":27,"affiliation":28,"role":29},"Hye-yeon Cho","Nowon Eulji University Hospital, Eulji University College of Medicine","PRINCIPAL_INVESTIGATOR",[31,36],{"name":32,"role":33,"phone":34,"phoneExt":24,"email":35},"Hye-Yeon Cho, MD","CONTACT","+82-2-970-8705","anesthesia_chy@eulji.ac.kr",{"name":37,"role":33,"phone":34,"phoneExt":24,"email":38},"Soojeong Kang, MD","20260034@eulji.ac.kr",[40],{"facility":41,"status":42,"city":43,"state":24,"zip":44,"country":45,"countryCode":24,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Nowon Eulji University Hospital","RECRUITING","Seoul","01830","South Korea",{"type":47,"coordinates":48},"Point",[49,50],126.9784,37.566,{"lat":50,"lon":49},[53],{"name":54,"role":33,"phone":34,"phoneExt":24,"email":35},"Hye-yeon Cho, MD",{"type":29,"investigatorFullName":27,"investigatorTitle":56,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"Assistant professor","100626846","timing-of-subcostal-tapb-combined-with-rectus-sheath-block-for-postoperative-pain-after-laparoscopic-cholecystectomy-100626846",false,"NCT07440940","Timing of Subcostal TAPB Combined With Rectus Sheath Block for Postoperative Pain After Laparoscopic Cholecystectomy","Effect of Timing of Ultrasound-Guided Subcostal Transversus Abdominis Plane Block Combined With Rectus Sheath Block on Postoperative Pain in Laparoscopic Cholecystectomy: A Prospective Randomized Controlled Trial","Inclusion Criteria:\n\n* Elective laparoscopic cholecystectomy\n* Adults aged 18 to 80 years\n* Ability to understand the study procedures and provide informed consent\n* American Society of Anesthesiologists (ASA) physical status I-III\n\nExclusion Criteria:\n\n* Presence of significant pain unrelated to the target disease that may interfere with pain assessment\n* Known allergy or contraindication to study medications (ropivacaine, acetaminophen, nefopam, or pethidine)\n* Planned single-port laparoscopic cholecystectomy\n* American Society of Anesthesiologists (ASA) physical status IV or higher\n* Infection of the abdominal wall or skin at the injection site, or anatomical abnormalities of the abdominal wall\n* Major neurological, psychiatric, or systemic diseases that may affect pain perception, treatment response, or study evaluation\n* Requirement for postoperative mechanical ventilation\n* Pregnancy or breastfeeding\n* Considered unsuitable for the study by the investigator\n* Refusal to participate or inability to provide informed consent","ALL","18 Years","80 Years",{"count":68,"type":69},96,"ESTIMATED","INTERVENTIONAL",[72],"NA","This prospective randomized controlled trial aims to evaluate whether the timing of ultrasound-guided subcostal transversus abdominis plane (TAP) block combined with rectus sheath block (RSB) affects postoperative pain in patients undergoing laparoscopic cholecystectomy.\n\nParticipants will be randomly assigned to receive the combined regional blocks either before surgical incision or after completion of surgery. The primary outcome is postoperative pain intensity measured using a numerical rating scale. Secondary outcomes include opioid consumption, incidence of postoperative nausea and vomiting, and other recovery parameters.\n\nThe results of this study may help optimize the timing of abdominal wall blocks to improve postoperative analgesia and recovery following laparoscopic cholecystectomy.",[75,76],"Postoperative Pain","Laparoscopic Cholecystectomy",[76,78,79,80],"Transversus Abdominis Plane Block","Rectus Sheath Block","Postoperative pain","2026-02-25",{"date":83,"type":84},"2026-02-27","ACTUAL",{"date":86,"type":84},"2026-02-23",{"date":88,"type":69},"2027-01-15",{"name":5,"class":6},1]