[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100427925":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":21,"centralContacts":25,"locations":33,"responsibleParty":51,"collaborators":10,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":57,"acronym":10,"eligibilityCriteria":58,"healthyVolunteers":59,"sex":60,"minAge":10,"maxAge":10,"enrollmentInfo":61,"targetDuration":10,"studyType":64,"phases":10,"briefSummary":65,"conditions":66,"keywords":10,"overallStatus":36,"whyStopped":10,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":77},{"fullName":5,"class":6},"Weill Medical College of Cornell University","OTHER",[8,12,15,18],{"label":9,"type":10,"description":11,"interventionNames":10},"Cohort 1: Tumor patients undergoing neurosurgery",null,"Samples of tumor tissue, blood, CSF, saliva, skull, and dura will be taken during neurosurgery from tumor patients meeting the inclusion criteria.",{"label":13,"type":10,"description":14,"interventionNames":10},"Parents of tumor patients","Saliva samples will be taken from parents of tumor patients meeting the inclusion criteria.",{"label":16,"type":10,"description":17,"interventionNames":10},"Cohort 2: Non-Tumor patients undergoing neurosurgery","Blood and CSF samples will be taken from non-tumor patients meeting the inclusion criteria.",{"label":19,"type":10,"description":20,"interventionNames":10},"Cohort 3: Autopsy tumor tissue donation","Post-mortem biospecimens such as whole brain, spinal cord, biofluids (e.g., cerebrospinal fluid and blood) and skin biopsy will be collected through autopsy donation from brain tumor patients meeting the inclusion criteria.",[22],{"name":23,"affiliation":5,"role":24},"Jeffrey Greenfield, M.D.","PRINCIPAL_INVESTIGATOR",[26,30],{"name":23,"role":27,"phone":28,"phoneExt":10,"email":29},"CONTACT","212-746-2363","jpgreenf@med.cornell.edu",{"name":31,"role":27,"phone":28,"phoneExt":10,"email":32},"Pediatric Neurosurgery","pediatricneurosurgery@med.cornell.edu",[34],{"facility":35,"status":36,"city":37,"state":37,"zip":38,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"Weill Cornell Medicine","RECRUITING","New York","10021","United States","US",{"type":42,"coordinates":43},"Point",[44,45],-74.00597,40.71427,{"lat":45,"lon":44},[48,49,50],{"name":23,"role":27,"phone":28,"phoneExt":10,"email":29},{"name":31,"role":27,"phone":28,"phoneExt":10,"email":32},{"name":23,"role":24,"phone":10,"phoneExt":10,"email":10},{"type":52,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100427925","tissue-collection-for-drug-screening-and-bioanalysis-100427925",false,"NCT04852354","Tissue Collection for Drug Screening and Bioanalysis","Inclusion Criteria for Tumor patients undergoing neurosurgery (cohort 1)\n\n1. Subject has presented with a suspected\u002Fconfirmed neoplastic CNS lesion and is undergoing a neurosurgical procedure in which CNS tissue and\u002For tumors associated with this tissue will be removed.\n2. There must be tissue available in excess of that required by neuropathology for diagnostic purposes.\n3. Subject of all ages included.\n4. Subjects who are pregnant can be included.\n5. Subjects who are neonates (0-4 weeks) can be included.\n\nInclusion Criteria for Non-tumor patients undergoing neurosurgery (cohort 2)\n\n1. Subject is between 4 weeks and 21 years of age and is undergoing a neurosurgical procedure at WCMC.\n2. Subject does not have a CNS tumor diagnosis.\n3. Subject should not be pregnant at the time of enrollment.\n\nInclusion Criteria for Autopsy tumor tissue donation (cohort 3)\n\n1. Subject of all ages included\n2. Subject has been diagnosed with a neoplastic CNS lesion at the time of passing.\n3. Subjects who are pregnant can be included.\n4. Subjects who are neonates (0-4 weeks) can be included.\n\nInclusion Criteria for parent of tumor patients\n\n1. Subject is the biological parent of a patient undergoing\u002F who underwent a neurosurgical procedure in which CNS tissue and\u002For tumors associated with this tissue will be\u002F was removed.\n2. Subject is the biological parent of patient enrolled in cohort 1.\n3. Subject is not pregnant at the time of enrollment.",true,"ALL",{"count":62,"type":63},500,"ESTIMATED","OBSERVATIONAL","The purpose of this study is to improve upon the knowledge currently available about central nervous system (CNS) tumors. We will study the different characteristics of these tumors using tissue samples collected during surgery and post-autopsy. The aim is to create tumor cell lines and models to test how they respond to different drugs. This research will help improve treatment options and identify new targets for therapy.",[67],"Central Nervous System Tumor","2025-12-09",{"date":70,"type":71},"2025-12-17","ACTUAL",{"date":73,"type":71},"2020-07-22",{"date":75,"type":63},"2029-07-22",{"name":5,"class":6},1]