[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100637970":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":30,"locations":40,"responsibleParty":52,"collaborators":25,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":62,"eligibilityCriteria":63,"healthyVolunteers":58,"sex":64,"minAge":65,"maxAge":66,"enrollmentInfo":67,"targetDuration":25,"studyType":70,"phases":71,"briefSummary":73,"conditions":74,"keywords":78,"overallStatus":86,"whyStopped":25,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"Assiut University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Thoracolumbar interfascial plane Block Group","EXPERIMENTAL","Patients will receive ultrasound-guided thoracolumbar interfascial plane block after induction of general anesthesia.",[13],"Procedure: Thoracolumbar interfascial plane block",{"label":15,"type":10,"description":16,"interventionNames":17},"Retrolaminar Block Group","Patients will receive ultrasound-guided retrolaminar block after induction of general anesthesia.",[18],"Procedure: Retrolaminar block",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Thoracolumbar interfascial plane block","Ultrasound-guided injection of local anesthetic into the fascial plane between the multifidus and longissimus muscles at the L3 level",[9],null,{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Retrolaminar block","Ultrasound-guided injection of local anesthetic posterior to the vertebral lamina at the L3 level.",[15],[31,36],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},"Rehab Mohamed Mostafa Mahmoud, MD (Candidate)","CONTACT","+201063303791","rehab.mohamed19@gmail.com",{"name":37,"role":33,"phone":38,"phoneExt":25,"email":39},"Mohamed Abo Elhassan, MD (candidate)","+201001311044","Aboelhassan@gmail.com",[41],{"facility":42,"status":25,"city":43,"state":25,"zip":25,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":25},"Assiut University Hospitals","Asyut","Egypt","EG",{"type":47,"coordinates":48},"Point",[49,50],31.18368,27.18096,{"lat":50,"lon":49},{"type":53,"investigatorFullName":54,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Rehab Mohamed Mostafa Mahmoud","Assistant Lecturer of Anesthesia, Intensive Care, and Pain Management","100637970","tlip-block-versus-retrolaminar-block-on-quality-of-recovery-after-posterior-lumbar-spine-fusion-surgery-100637970",false,"NCT07609212","TLIP Block Versus Retrolaminar Block on Quality of Recovery After Posterior Lumbar Spine Fusion Surgery","Thoracolumbar Interfascial Plane Block Versus Retrolaminar Block on Quality of Recovery After Posterior Lumbar Spine Fusion Surgery: A Prospective Randomized Controlled Trial","TLIP-RLB-QoR","Inclusion Criteria:\n\n* Adult patients aged 18-65 years\n* Male and female patients\n* Scheduled for elective one- or two-level posterior lumbar instrumented fusion surgery under general anesthesia\n* ASA physical status I-III\n* BMI \\\u003C 35 kg\u002Fm²\n* Willing to participate and provide informed consent\n\nExclusion Criteria:\n\n* Patient refusal to participate\n* Coagulopathy or anticoagulant therapy\n* Infection at the site of block injection\n* Known allergy to local anesthetics\n* Chronic opioid use (\\>3 months)\n* Severe hepatic, renal, or cardiac dysfunction\n* Neurological deficits interfering with pain assessment\n* Pregnancy or lactation","ALL","18 Years","65 Years",{"count":68,"type":69},70,"ESTIMATED","INTERVENTIONAL",[72],"NA","This prospective randomized controlled study aims to compare the effects of ultrasound-guided thoracolumbar interfascial plane (TLIP) block versus retrolaminar block on postoperative quality of recovery in patients undergoing posterior lumbar spine fusion surgery. Despite advances in surgical techniques, lumbar spine fusion is associated with significant postoperative pain, which may delay recovery and increase opioid consumption.\n\nRecent approaches emphasize multimodal analgesia and opioid-sparing strategies, including regional anesthesia techniques. Interfascial plane blocks, such as TLIP and retrolaminar block, have gained attention due to their safety and effectiveness in targeting the dorsal rami of spinal nerves supplying the posterior spinal structures.\n\nThe primary outcome of this study is postoperative quality of recovery assessed using the Quality of Recovery-15 (QoR-15) questionnaire at 24 hours. Secondary outcomes include pain scores, opioid consumption, time to ambulation, time to oral intake, and postoperative complications.",[75,76,77],"Postoperative Pain","Spinal Fusion Surgery","Degenerative Lumbar Spine Diseases",[79,80,81,82,83,84,85],"TLIP Block","Retrolaminar Block","Regional Anesthesia","Quality of Recovery","QoR-15","Lumbar Spine Surgery","Postoperative Analgesia","NOT_YET_RECRUITING","2026-05-21",{"date":89,"type":90},"2026-05-27","ACTUAL",{"date":92,"type":69},"2026-06",{"date":94,"type":69},"2027-06",{"name":5,"class":6},1]