[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100576199":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":28,"centralContacts":33,"locations":38,"responsibleParty":54,"collaborators":56,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":67,"eligibilityCriteria":68,"healthyVolunteers":63,"sex":69,"minAge":70,"maxAge":25,"enrollmentInfo":71,"targetDuration":25,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":25,"overallStatus":40,"whyStopped":25,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"Karolinska Institutet","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Arthroscopic lysis and lavage","ACTIVE_COMPARATOR","Arthroscopic lysis and lavage refers to an arthroscopic procedure where the temporomandibular joint is rinsed with saline solution and where the joint capsule is distended and where adhesions are lysated bluntly. This is mananged through one port of entry into the joint.",[13],"Procedure: Arthroscopic lysis and lavage",{"label":15,"type":16,"description":17,"interventionNames":18},"Operative arthroscopy","EXPERIMENTAL","Operative arthroscopy refers to an arthroscopic procedure where the temporomandibular joint is accessed via two ports of entry. The joint is rinsed with saline solution and the anterior disc attachment is released with cold ablation where after the posterior attachment is sclerosed with the coagulation mode on the coblator.",[19],"Procedure: Operative arthroscopy",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Arthroscopic lysis and lavage refers to an arthroscopic procedure where the temporomandibular joint is rinsed with saline solution and where the joint capsule is distended and where adhesions are lysated bluntly.",[9],null,{"type":22,"name":15,"description":17,"armGroupLabels":27,"otherNames":25},[15],[29],{"name":30,"affiliation":31,"role":32},"Mattias Ulmner, DDS, PhD","Karolinska Institutet, Department of Dental Medicine","PRINCIPAL_INVESTIGATOR",[34],{"name":30,"role":35,"phone":36,"phoneExt":25,"email":37},"CONTACT","+46 707648141","mattias.ulmner@ki.se",[39],{"facility":5,"status":40,"city":41,"state":25,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"RECRUITING","Huddinge","14104","Sweden","SE",{"type":46,"coordinates":47},"Point",[48,49],17.98192,59.23705,{"lat":49,"lon":48},[52],{"name":53,"role":35,"phone":36,"phoneExt":25,"email":37},"Mattias Ulmner",{"type":32,"investigatorFullName":53,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Lecturer",[57,59],{"name":58,"class":6},"Karolinska University Hospital",{"name":60,"class":6},"Eastmaninstitutet","100576199","tmj-arthroscopic-lysis-and-lavage-compared-to-operative-arthroscopy-in-disc-displacement-with-reduction-100576199",false,"NCT06782191","TMJ Arthroscopic Lysis and Lavage Compared to Operative Arthroscopy in Disc Displacement With Reduction.","Temporomandibular Joint Arthroscopic Lysis and Lavage Compared to Operative Arthroscopy in Disc Displacement With Reduction: a Randomised, Double-blind, Controlled Trial","ALLOAA","Inclusion Criteria:\n\n* Uni- or bilateral DDwR verified with clinical and magnetic resonance imaging (MRI) findings\n* TMJ pain ≥ 3 (NRS) and\u002For TMJ disability ≥ 3 (NRS)\n* Age ≥ 18 years\n\nExclusion Criteria:\n\n* Prior open TMJ surgery\n* Patient diagnosed with rheumatologic joint disease\n* ASA (American Society of Anaesthesiologists) \\> 3\n* Patient unable to verify informed consent","ALL","18 Years",{"count":72,"type":73},96,"ESTIMATED","INTERVENTIONAL",[76],"NA","The goal of this clinical trial is to compare the intervention arthroscopic lysis and lavage to the intervention operative arthroscopy in treating disabling and painful temporomandibular joint disc displacement with reduction. The main questions it aims to answer are:\n\n* Which surgical method that best improves mouth opening capacity, TMJ pain, and TMJ disability?\n* If any pre- or peri-operative variable\u002F-s could be identified as a predictor for surgical outcome? Researchers will compare arthroscopic lysis and lavage to operative arthroscopy to see if operative arthroscopy works better to treat temporomandibular joint disc displacement.\n\nParticipants will:\n\n* Have one of the two interventions under general anesthesia, not knowing which intervention.\n* Visit an external clinic for regular checkups at 1, 3, 6, 12, and 24 months after surgery.\n* Answer three different quality of life surveys at the checkups.",[79,80],"Temporomandibular Joint Disc Displacement, With Reduction","Temporomandibular Disorders (TMD)","2025-06-27",{"date":83,"type":84},"2025-06-29","ACTUAL",{"date":86,"type":84},"2025-04-01",{"date":88,"type":73},"2031-02",{"name":5,"class":6},1]