[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100547264":3},{"organization":4,"armGroups":7,"interventions":23,"overallOfficials":30,"centralContacts":34,"locations":39,"responsibleParty":53,"collaborators":29,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":29,"eligibilityCriteria":61,"healthyVolunteers":62,"sex":63,"minAge":64,"maxAge":65,"enrollmentInfo":66,"targetDuration":29,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":75,"overallStatus":79,"whyStopped":29,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"Tianjin Eye Hospital","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Test group A (strong higher-order aberrations group)","EXPERIMENTAL","Simultaneous myopic defocus and strong higher-order aberrations lenses",[13],"Device: frame lens",{"label":15,"type":10,"description":16,"interventionNames":17},"Test group B (medium higher-order aberrations group)","Both myopic defocus and medium higher-order aberrations lenses",[13],{"label":19,"type":20,"description":21,"interventionNames":22},"control groups（HOYA MiYOSMART）","ACTIVE_COMPARATOR","HOYA MiYOSMART lenses",[13],[24],{"type":25,"name":26,"description":27,"armGroupLabels":28,"otherNames":29},"DEVICE","frame lens","A randomized block group design was used to randomly assign the included study subjects. The appropriate randomization number and random allocation scheme will be given after enrollment.",[9,15,19],null,[31],{"name":32,"affiliation":5,"role":33},"Xiaoqin Chen, MD","PRINCIPAL_INVESTIGATOR",[35],{"name":32,"role":36,"phone":37,"phoneExt":29,"email":38},"CONTACT","+8618202681988","chenxq017@163.com",[40],{"facility":5,"status":29,"city":41,"state":29,"zip":29,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Tianjin","China","CN",{"type":45,"coordinates":46},"Point",[47,48],117.17667,39.14222,{"lat":48,"lon":47},[51],{"name":52,"role":36,"phone":37,"phoneExt":29,"email":38},"xiaoqin Chen",{"type":54,"investigatorFullName":29,"investigatorTitle":29,"investigatorAffiliation":29,"oldNameTitle":29,"oldOrganization":29},"SPONSOR","100547264","to-evaluate-the-efficacy-and-safety-of-an-defocus-lens-in-slowing-the-progression-of-myopia-100547264",false,"NCT06405711","To Evaluate the Efficacy and Safety of an Defocus Lens in Slowing the Progression of Myopia","To Evaluate the Efficacy and Safety of an Defocus Lens in Slowing the Progression of Myopia：a Prospective Study","Inclusion Criteria:\n\n* The subjects had spherical RE of -1.00 to -6.00 D, astigmatism ≤ 1.50 D, anisometropia ≤ 1.50 D\n* the best corrected visual acuity in the left and right eyes subjective optometry is greater than or equal to 1.0\n\nExclusion Criteria:\n\n* Candidate subjects were excluded from the study if they had strabismus, ocular limitations, or systemic abnormalities affecting vision and ocular motility",true,"ALL","8 Years","13 Years",{"count":67,"type":68},138,"ESTIMATED","INTERVENTIONAL",[71],"NA","To confirm the efficacy of DIMS lenses in controlling myopia progression, we planned a prospective, single-centre, randomised, double-blind, controlled, non-inferiority clinical study.",[74],"Myopia, Progressive",[76,77,78],"myopia","axial length","defocus","NOT_YET_RECRUITING","2024-05-05",{"date":82,"type":83},"2024-05-08","ACTUAL",{"date":85,"type":68},"2024-05",{"date":87,"type":68},"2026-12",{"name":5,"class":6},1]