[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100507013":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":12,"centralContacts":16,"locations":21,"responsibleParty":40,"collaborators":7,"id":42,"slug":43,"hasResults":44,"nctId":45,"briefTitle":46,"officialTitle":46,"acronym":7,"eligibilityCriteria":47,"healthyVolunteers":44,"sex":48,"minAge":49,"maxAge":7,"enrollmentInfo":50,"targetDuration":7,"studyType":53,"phases":7,"briefSummary":54,"conditions":55,"keywords":7,"overallStatus":23,"whyStopped":7,"lastUpdateSubmitDate":57,"lastUpdatePostDateStruct":58,"startDateStruct":61,"completionDateStruct":63,"leadSponsor":65,"locationsCount":66},{"fullName":5,"class":6},"University of Minnesota","OTHER",null,[9],{"type":6,"name":10,"description":11,"armGroupLabels":7,"otherNames":7},"No intervention","This is an observational study",[13],{"name":14,"affiliation":5,"role":15},"Sudarshan Setty, MD","PRINCIPAL_INVESTIGATOR",[17],{"name":18,"role":19,"phone":7,"phoneExt":7,"email":20},"Candace Nelson","CONTACT","nelso377@umn.edu",[22],{"facility":5,"status":23,"city":24,"state":25,"zip":26,"country":27,"countryCode":28,"cosmosGeoPoint":29,"geoPoint":34,"contacts":35},"RECRUITING","Minneapolis","Minnesota","55455","United States","US",{"type":30,"coordinates":31},"Point",[32,33],-93.26384,44.97997,{"lat":33,"lon":32},[36],{"name":37,"role":19,"phone":38,"phoneExt":7,"email":39},"Pankhura Gupta","763-268-9823","gupta359@umn.edu",{"type":41,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR","100507013","to-investigate-airway-oxygen-concentrations-during-rigid-bronchoscopy-procedures-performed-with-high-frequency-jet-ventilation-100507013",false,"NCT05881863","To Investigate Airway Oxygen Concentrations During Rigid Bronchoscopy Procedures Performed With High Frequency Jet Ventilation","Inclusion Criteria:\n\n* Patients undergoing rigid bronchoscopy for treatment of central airway obstruction at FV UMMC will be identified.\n* 18 years or older\n* Need rigid bronchoscopy as pre-determined by the interventional pulmonologist\n\nExclusion Criteria:\n\n* Refusal to sign consent\n* Pregnant patients\n* Hemodynamic instability defined as continuous infusion of medication in order to support blood pressure and\u002For heart rate\u002Frhythm\n* Respiratory instability defined as SpO2\\<90% with \\>90% supplemental oxygen.\n* Ineligible for rigid bronchoscopic intubation\n* Latex allergy\n* Evidence of fistulous airway\n* Active Bronchopleural fistula","ALL","18 Years",{"count":51,"type":52},50,"ESTIMATED","OBSERVATIONAL","Thermal ablation (use of treatment modalities that generate heat) has become a widely used tool for treatment of central airway obstruction (e.g. laser, electrocautery, radiofrequency, and argon plasma coagulation). However, this method carries with it an increased risk for airway fire - a surgical fire that occurs in a patient's airway and could also include a fire in the attached breathing circuit. To decrease the risk of airway fire during mechanical ventilation with an endotracheal tube, the concentration of inspired oxygen (FiO2) is set below 40% while waiting for end tidal oxygen concentration (EtO2) to fall below 40% prior to starting thermal ablation. There is no published literature describing O2 concentration within the airways (AiO2) during jet ventilation with rigid bronchoscopy. The co-investigators of this study have recently collected data on AiO2 during rigid bronchoscopy using manual low frequency jet ventilation\u002Fhigh frequency jet ventilation with a period of apnea. The intent of this study is to measure the time taken for the central airway oxygen concentration to drop from 90 to 40% when the \"laser mode\" is activated on the Monsoon jet ventilator. Ventilation is continued during \"laser mode.\"",[56],"Central Airway Obstruction","2026-01-05",{"date":59,"type":60},"2026-01-07","ACTUAL",{"date":62,"type":60},"2024-01-12",{"date":64,"type":52},"2026-12-31",{"name":5,"class":6},1]