[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100494561":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":26,"locations":37,"responsibleParty":57,"collaborators":25,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":65,"eligibilityCriteria":66,"healthyVolunteers":61,"sex":67,"minAge":68,"maxAge":69,"enrollmentInfo":70,"targetDuration":25,"studyType":73,"phases":74,"briefSummary":76,"conditions":77,"keywords":83,"overallStatus":40,"whyStopped":25,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":97},{"fullName":5,"class":6},"Centre hospitalier de l'Université de Montréal (CHUM)","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"MAD-active","ACTIVE_COMPARATOR","MAD = mandibular advancement appliance, in 60-70% forward position from maximum possible jaw advancement for a given participant",[13],"Device: Ronco-Onco and MAD",{"label":15,"type":16,"description":17,"interventionNames":18},"Neutral MAD- control","SHAM_COMPARATOR","Mandibular advancement appliance in neurtral-control position, 10-20% of advancement - a non functional position to open upper airway",[13],[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DEVICE","Ronco-Onco and MAD","Comparison of active over a neutral mandibular advacement oral appliance to assess tolerance and efficacy in oropharyngeal cancer individuals in managing snoring and sleep apnea following radiotherapy of oropharynx.",[9,15],null,[27,32],{"name":28,"role":29,"phone":30,"phoneExt":25,"email":31},"Gilles Lavigne, DMD, PhD","CONTACT","514-343-2310","gilles.lavigne@umontreal.ca",{"name":33,"role":29,"phone":34,"phoneExt":35,"email":36},"Matthieu Schmittbuhl, DDS, PhD","514 890-8000","26686","matthieu.schmittbuhl@umontreal.ca",[38],{"facility":39,"status":40,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"CHUM","RECRUITING","Montreal","Quebec","H3X 3E4","Canada","CA",{"type":47,"coordinates":48},"Point",[49,50],-73.58781,45.50884,{"lat":50,"lon":49},[53],{"name":54,"role":29,"phone":55,"phoneExt":56,"email":25},"Karine Peaupert","514-890-8000","14730",{"type":58,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100494561","tolerance-and-benefits-of-mandibular-advanced-device-for-snoring-and-sleep-apnea-in-oropharyngeal-cancer-100494561",false,"NCT05719779","Tolerance and Benefits of Mandibular Advanced Device for Snoring and Sleep Apnea in Oropharyngeal Cancer.","Evaluation of the Tolerance and Benefits of Mandibular Advanced Device for Snoring and Sleep Apnea in Patients With Oropharyngeal Cancer: Mixed Design Study.","Ronco-Onco","Inclusion Criteria:\n\n* oropharyngeal cancer diagnosis\n* 18 years of age and over\n* female or male; ratio of 1\u002F4 toward men\n* had received RTH in the Department of Radiation Oncology,\n* reporting snoring and\u002For respiratory cessation complaints during sleep,\n\nExclusion Criteria:\n\n* pregnant or breastfeeding woman;\n* edentation preventing retention of the oral appliance;\n* taking opioid or anxiolitic type medications;\n* history of major depression,\n* uncontrolled hypertension,\n* history of stroke;\n* under treatment with CPAP for sleep apnea;\n* regular and intense orofacial pain;\n* under pharmacological treatment for insomnia;\n* excessive alcohol or drug use (e.g., cannabis, opioid).","ALL","18 Years","65 Years",{"count":71,"type":72},35,"ESTIMATED","INTERVENTIONAL",[75],"NA","Evaluation of the Tolerance and Benefits of Mandibular Advanced Device (MAD) for Snoring and Sleep Apnea in Patients with Oropharyngeal Cancer (OPC): Mixed Design Study.",[78,79,80,81,82],"Oral Cancer","Pharynx Cancer","Sleep Apnea","Snoring","Oral Squamous Cell Carcinoma",[84,85,86,87],"oropharyngeal cancer","snoring","sleep apnea","oral appliance","2024-08-14",{"date":90,"type":91},"2024-08-15","ACTUAL",{"date":93,"type":91},"2023-02-03",{"date":95,"type":72},"2025-12-30",{"name":5,"class":6},1]