[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100503644":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":26,"centralContacts":30,"locations":40,"responsibleParty":78,"collaborators":10,"id":80,"slug":81,"hasResults":82,"nctId":83,"briefTitle":84,"officialTitle":85,"acronym":10,"eligibilityCriteria":86,"healthyVolunteers":82,"sex":87,"minAge":10,"maxAge":88,"enrollmentInfo":89,"targetDuration":10,"studyType":92,"phases":10,"briefSummary":93,"conditions":94,"keywords":96,"overallStatus":43,"whyStopped":10,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":109},{"fullName":5,"class":6},"Wake Forest University Health Sciences","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Total intravenous anesthesia (TIVA)",null,"TIVA is achieved without inhalational agents and may be performed in cases where patients have an intravenous line in place prior to induction of anesthesia",[13],"Other: Total intravenous anesthesia (TIVA)",{"label":15,"type":10,"description":16,"interventionNames":17},"Sevoflurane initiated intravenous anesthesia (SIIVA)","SIIVA is a modification of TIVA in the setting where a patient does not tolerate the insertion of an intravenous line prior to induction of anesthesia. The patient undergoes induction of anesthesia with sevoflurane and transition to Propofol IV anesthesia for maintenance once the intravenous line is in place and discontinues the inhalational agent, sevoflurane.",[18],"Other: Sevoflurane initiated intravenous anesthesia (SIIVA)",[20,23],{"type":6,"name":9,"description":21,"armGroupLabels":22,"otherNames":10},"TIVA anesthetic -no inhalational gases for surgery",[9],{"type":6,"name":15,"description":24,"armGroupLabels":25,"otherNames":10},"SIIVA - sevoflurane anesthetic gases for surgery",[15],[27],{"name":28,"affiliation":5,"role":29},"Thomas \"Wes\" Templeton, MD","PRINCIPAL_INVESTIGATOR",[31,36],{"name":32,"role":33,"phone":34,"phoneExt":10,"email":35},"Wes Templeton, MD","CONTACT","336-716-4498","ttemplet@wakehealth.edu",{"name":37,"role":33,"phone":38,"phoneExt":10,"email":39},"Lynne Harris, BSN","336-716-8791","lcharris@wakehealth.edu",[41,60],{"facility":42,"status":43,"city":44,"state":45,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"Atrium Health Wake Forest Baptist","RECRUITING","Winston-Salem","North Carolina","27157","United States","US",{"type":50,"coordinates":51},"Point",[52,53],-80.24422,36.09986,{"lat":53,"lon":52},[56,57,59],{"name":28,"role":33,"phone":34,"phoneExt":10,"email":35},{"name":58,"role":33,"phone":38,"phoneExt":10,"email":39},"Lynnette C Harris, BSN",{"name":28,"role":29,"phone":10,"phoneExt":10,"email":10},{"facility":61,"status":62,"city":63,"state":10,"zip":10,"country":64,"countryCode":65,"cosmosGeoPoint":66,"geoPoint":70,"contacts":71},"Perth Children's Hospital","NOT_YET_RECRUITING","Perth","Australia","AU",{"type":50,"coordinates":67},[68,69],115.8614,-31.95224,{"lat":69,"lon":68},[72,75],{"name":73,"role":33,"phone":74,"phoneExt":10,"email":10},"Britta von Ungern-Sternberg, Prof","+61(0)8 6456 4806",{"name":76,"role":33,"phone":74,"phoneExt":10,"email":77},"Lliana Slevin","Lliana.Slevin@health.wa.gov.au",{"type":79,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100503644","total-intravenous-anesthesia-tivasevoflurane-initiated-intravenous-anesthesia-siiva-in-pediatric-patients-100503644",false,"NCT05837936","Total Intravenous Anesthesia (TIVA)\u002FSevoflurane Initiated Intravenous Anesthesia (SIIVA) in Pediatric Patients","A Prospective Observational Study Evaluating Extubation Criteria in Children Less 10 Years of Age and Younger Undergoing Intravenous Anesthesia","Inclusion Criteria:\n\n* Pediatric patients \\\u003C10 years of age\n* Undergoing elective or emergency surgery with planned airway instrumentation with an endotracheal tube (ETT)\n* Patients having general anesthesia with a planned SIIVA or TIVA technique\n* Patients with an end tidal agent concentration of Sevoflurane\\\u003C0.1% at the time of emergence and extubation\n* following sevoflurane induction to place IV\n\nExclusion Criteria:\n\n* History of home oxygen use or ventilator dependence\n* Patients with cyanotic congenital heart disease\n* Patients undergoing anesthesia for imaging procedures alone\n* Patients intended to be managed with supraglottic airway\n* Patients having an anesthesia time \\\u003C 30 minutes\n* Monitored Anesthesia Care (not general anesthesia)\n* Patients with contraindication to receiving Propofol (i.e. mitochondrial myopathy)","ALL","9 Years",{"count":90,"type":91},600,"ESTIMATED","OBSERVATIONAL","Because Propofol is the primary \"anesthetic agent,\" and inhalational agents remain in trace quantities at the end of the procedure Sevoflurane initiated intravenous anesthesia (SIIVA) or not present at all Total intravenous anesthesia (TIVA) it is likely that different criteria may be predictive of extubation success in these patients compared to inhalational anesthesia.",[95],"Extubation",[97,98,99],"anesthesia","Propofol","inhalational agents","2025-12-10",{"date":102,"type":103},"2025-12-18","ACTUAL",{"date":105,"type":103},"2023-03-28",{"date":107,"type":91},"2028-03",{"name":5,"class":6},2]