[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100556334":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":25,"locations":31,"responsibleParty":50,"collaborators":19,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":19,"eligibilityCriteria":58,"healthyVolunteers":54,"sex":59,"minAge":60,"maxAge":19,"enrollmentInfo":61,"targetDuration":19,"studyType":64,"phases":65,"briefSummary":67,"conditions":68,"keywords":71,"overallStatus":34,"whyStopped":19,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":82},{"fullName":5,"class":6},"Wuerzburg University Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Trabeculopuncture","EXPERIMENTAL","Individuals undergo neodymium-doped yttrium aluminum garnet (Nd:YAG) trabeculopuncture prior to ab interno trabeculectomy.",[13],"Diagnostic Test: Trabeculopuncture",[15],{"type":16,"name":9,"description":17,"armGroupLabels":18,"otherNames":19},"DIAGNOSTIC_TEST","Trabeculopuncture is performed with a Nd:YAG laser on the trabecular meshwork. Four punctures are created along the 180° nasal trabecular meshwork.",[9],null,[21],{"name":22,"affiliation":23,"role":24},"Daniel Kampik, MD, PhD","Department of Ophthalmology University Hospital Würzburg","PRINCIPAL_INVESTIGATOR",[26],{"name":27,"role":28,"phone":29,"phoneExt":19,"email":30},"Raoul Verma-Fuehring, MD","CONTACT","+49 93120120662","vermafuehr_R@ukw.de",[32],{"facility":33,"status":34,"city":35,"state":36,"zip":37,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"Uniklinikum Würzburg","RECRUITING","Würzburg","Bavaria","97080","Germany","DE",{"type":41,"coordinates":42},"Point",[43,44],9.95121,49.79391,{"lat":44,"lon":43},[47],{"name":48,"role":28,"phone":49,"phoneExt":19,"email":30},"Raoul Verma-Führing, MD","0049 93120120662",{"type":51,"investigatorFullName":19,"investigatorTitle":19,"investigatorAffiliation":19,"oldNameTitle":19,"oldOrganization":19},"SPONSOR","100556334","trabeculopuncture-as-predictive-test-for-the-success-of-ab-interno-trabeculectomy-100556334",false,"NCT06523751","Trabeculopuncture as Predictive Test for the Success of Ab Interno Trabeculectomy","Determining Distal Outflow Tract Function in Open Angle Glaucoma as a Predictive Test for the Success of Ab Interno Trabeculectomy","Inclusion Criteria:\n\n* individuals ≥ 18 years of age\n* clinical diagnosis of: primary open angle glaucoma, pigmentary glaucoma, or pseudoexfoliation glaucoma\n* uncontrolled intraocular pressure (IOP) with maximally tolerated medical therapy\n* progressive thinning of retinal nerve fiber layer assessed by Spectral domain optical coherence tomography (p \\\u003C 0.05)\n* progression of visual field defects\n* visually significant cataract and indication to reduce IOP or glaucoma medication burden\n\nExclusion Criteria:\n\n* clinical diagnosis of neovascular glaucoma, angle-closure glaucoma, uveitic glaucoma, neovascular glaucoma\n* prior glaucoma surgery\n* preexisting conditions affecting the episcleral venous pressure including Grave's ophthalmopathy, Sturge-Weber syndrome, Arteriovenous fistulas (carotid-cavernous fistula)","ALL","18 Years",{"count":62,"type":63},55,"ESTIMATED","INTERVENTIONAL",[66],"NA","The purpose of this study is to perform trabeculopuncture a test to determine the distal outflow tract function to predict the success of ab interno trabeculectomy.",[69,70],"Open Angle Glaucoma","Pseudoexfoliation Glaucoma",[72,9,69],"Ab Interno Trabeculectomy","2025-04-02",{"date":75,"type":76},"2025-04-03","ACTUAL",{"date":78,"type":76},"2023-06-13",{"date":80,"type":63},"2026-01-31",{"name":5,"class":6},1]