[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100640251":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":25,"locations":32,"responsibleParty":45,"collaborators":10,"id":47,"slug":48,"hasResults":49,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":10,"eligibilityCriteria":53,"healthyVolunteers":49,"sex":54,"minAge":55,"maxAge":10,"enrollmentInfo":56,"targetDuration":10,"studyType":59,"phases":10,"briefSummary":60,"conditions":61,"keywords":66,"overallStatus":71,"whyStopped":10,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":81},{"fullName":5,"class":6},"Bursa Sevket Yilmaz Training and Research Hospital","OTHER_GOV",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Elective CABG Cohort",null,"Adult patients who underwent elective coronary artery bypass grafting with cardiopulmonary bypass between January 1, 2022 and December 31, 2025. Patients will be included retrospectively from hospital records, electronic medical records, laboratory databases, and archived patient files. No intervention, experimental treatment, or additional testing will be performed as part of this study.",[13],"Other: Early Postoperative Phenotype Classification",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"OTHER","Early Postoperative Phenotype Classification","Patients will be retrospectively classified into phenotype groups based on early postoperative inflammatory and renal biomarker trajectories. This classification is analytical only and does not involve any intervention, treatment assignment, or additional testing.",[9],[21],{"name":22,"affiliation":23,"role":24},"Gürcan Güler","University of Health Sciences Bursa Yüksek İhtisas Training and Research Hospital","PRINCIPAL_INVESTIGATOR",[26,30],{"name":22,"role":27,"phone":28,"phoneExt":10,"email":29},"CONTACT","+90 541 975 0407","gurcanguler.45@gmail.com",{"name":22,"role":27,"phone":31,"phoneExt":10,"email":29},"+90 541 975 04 07",[33],{"facility":34,"status":10,"city":35,"state":10,"zip":10,"country":36,"countryCode":10,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"University of Health Sciences, Bursa Yuksek Ihtisas Training and Research Hospital","Bursa","Turkey (Türkiye)",{"type":38,"coordinates":39},"Point",[40,41],29.06013,40.19559,{"lat":41,"lon":40},[44],{"name":22,"role":27,"phone":28,"phoneExt":10,"email":29},{"type":24,"investigatorFullName":22,"investigatorTitle":46,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Specialist Physician, Department of Anesthesiology and Reanimation","100640251","trajectory-based-phenotyping-after-coronary-artery-bypass-surgery-100640251",false,"NCT07598682","Trajectory-Based Phenotyping After Coronary Artery Bypass Surgery","Early Postoperative Trajectory-Based Phenotyping Improves Risk Stratification Beyond EuroSCORE in Patients Undergoing Coronary Artery Bypass Grafting","Inclusion Criteria:\n\n* Adult patients aged 18 years or older\n* Patients who underwent elective on-pump coronary artery bypass grafting\n* Patients operated between January 1, 2022 and December 31, 2025\n* Patients with available perioperative clinical and laboratory data required for analysis\n\nExclusion Criteria:\n\n* Patients undergoing emergency surgery\n* Patients undergoing concomitant valve surgery\n* Patients with missing or inconsistent key clinical or laboratory data","ALL","18 Years",{"count":57,"type":58},1000,"ESTIMATED","OBSERVATIONAL","Coronary artery bypass grafting is a commonly performed heart surgery, but patients may have different risks for postoperative complications even when their preoperative risk scores are similar. EuroSCORE II is widely used to estimate surgical risk before cardiac surgery, but it may not fully reflect how the body responds during the early postoperative period.\n\nThis retrospective observational study will evaluate adult patients who underwent elective coronary artery bypass grafting with cardiopulmonary bypass between January 1, 2022 and December 31, 2025. The study will use existing hospital records and laboratory data. No additional treatment, test, or intervention will be given to patients as part of this study.\n\nThe main aim is to examine whether early postoperative changes in inflammatory and renal laboratory markers can identify different patient subgroups, called phenotypes. These markers include neutrophil-to-lymphocyte ratio, systemic immune-inflammation index, triglyceride-glucose index, and serum creatinine. The study will evaluate whether these phenotype groups are associated with postoperative acute kidney injury and prolonged intensive care unit stay.\n\nThe study will also assess whether this early postoperative phenotype-based classification provides additional risk information beyond EuroSCORE II.",[62,63,64,65],"Coronary Artery Bypass Grafting","Postoperative Acute Kidney Injury","Postoperative Complications","Risk Stratification",[67,68,69,70],"Coronary artery bypass grafting","Postoperative phenotyping","EuroSCORE II","Risk stratification","NOT_YET_RECRUITING","2026-05-13",{"date":74,"type":75},"2026-05-20","ACTUAL",{"date":77,"type":58},"2026-05-07",{"date":79,"type":58},"2026-07-01",{"name":5,"class":6},1]