[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100597399":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":21,"locations":20,"responsibleParty":31,"collaborators":20,"id":33,"slug":34,"hasResults":35,"nctId":36,"briefTitle":37,"officialTitle":37,"acronym":20,"eligibilityCriteria":38,"healthyVolunteers":35,"sex":39,"minAge":40,"maxAge":20,"enrollmentInfo":41,"targetDuration":20,"studyType":44,"phases":45,"briefSummary":47,"conditions":48,"keywords":50,"overallStatus":52,"whyStopped":20,"lastUpdateSubmitDate":53,"lastUpdatePostDateStruct":54,"startDateStruct":57,"completionDateStruct":59,"leadSponsor":61,"locationsCount":20},{"fullName":5,"class":6},"Sheba Medical Center","OTHER_GOV",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients with suspected or confirmed diagnosis of Eosinophilic esophagitis","EXPERIMENTAL","Patients will undergo trans-cervical or abdominal ultrasound before their scheduled upper endoscopy with biopsies.",[13],"Device: Trans cervical or abdominal ultrasound",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DEVICE","Trans cervical or abdominal ultrasound","ultrasound assessment before the scheduled upper endoscopy.",[9],null,[22,28],{"name":23,"role":24,"phone":25,"phoneExt":26,"email":27},"Asaf Levartovsky, MD","CONTACT","97235307072","7072","asaflevartovsky.research@sheba.health.gov.il",{"name":29,"role":24,"phone":25,"phoneExt":26,"email":30},"Revital Dvir","revital.dvir@sheba.health.gov.il",{"type":32,"investigatorFullName":20,"investigatorTitle":20,"investigatorAffiliation":20,"oldNameTitle":20,"oldOrganization":20},"SPONSOR","100597399","trans-cervical-and-trans-abdominal-ultrasound-for-monitoring-esophageal-thickness-in-eosinophilic-esophagitis-100597399",false,"NCT07057986","Trans-Cervical and Trans-abdominal Ultrasound for Monitoring Esophageal Thickness in Eosinophilic Esophagitis","Inclusion Criteria:\n\n* Age ≥18 years.\n* Suspected or confirmed diagnosis of EoE based on clinical symptoms (e.g., dysphagia, food impaction).\n* Scheduled for upper endoscopy with biopsies.\n* Able and willing to consent to participation.\n\nExclusion Criteria:\n\n* Prior esophageal surgery or anatomical abnormalities.\n* Presence of other gastrointestinal disorders affecting the esophagus (e.g., esophageal cancer, achalasia, Barrett's esophagus).\n* Pregnancy.\n* Inability to undergo US due to anatomical or physical limitations.","ALL","18 Years",{"count":42,"type":43},100,"ESTIMATED","INTERVENTIONAL",[46],"NA","Eosinophilic Esophagitis (EoE) is a chronic inflammatory disease characterized by eosinophilic infiltration of the esophageal mucosa, leading to symptoms of dysphagia and food impaction. Currently, upper endoscopy with biopsy is the gold standard for diagnosis and disease monitoring, but it is invasive, costly, and associated with procedural risks. The investigators want to use ultrasound imaging as a non-invasive assessment of esophageal wall thickness as a surrogate marker for mucosal inflammation.\n\nParticipants will undergo ultrasound assessment at the same day of endoscopy, and than after 3-6 months (optional). The correlation between US-measured esophageal thickness and histological eosinophil counts will be measured.",[49],"Eosinophilic Esophagitis (EoE)",[51],"eosinophilic esophagitis","NOT_YET_RECRUITING","2025-07-24",{"date":55,"type":56},"2025-07-29","ACTUAL",{"date":58,"type":43},"2025-08-01",{"date":60,"type":43},"2028-08-01",{"name":5,"class":6}]