[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100642462":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":26,"centralContacts":31,"locations":40,"responsibleParty":55,"collaborators":25,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":64,"eligibilityCriteria":65,"healthyVolunteers":60,"sex":66,"minAge":67,"maxAge":68,"enrollmentInfo":69,"targetDuration":25,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":79,"overallStatus":43,"whyStopped":25,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"Sun Yat-sen University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"robotic TME","ACTIVE_COMPARATOR","For patients with low rectal cancer, the da Vinci multi-arm robotic system is used to perform total mesorectal excision (TME). The procedure includes vascular ligation, mesenteric mobilization, distal bowel transection beyond the tumor, and anastomosis, all completed transabdominally with robotic assistance.",[13],"Procedure: robotic surgery vs transanal total mesorectal excsion",{"label":15,"type":16,"description":17,"interventionNames":18},"taTME","EXPERIMENTAL","For patients with low rectal cancer, a combined transanal and transabdominal approach is used to complete the total mesorectal excision (TME). A purse-string suture is placed approximately 1 cm below the distal tumor margin, followed by insertion of a single-port device. The mesorectum is then mobilized from bottom to top. Vascular ligation is performed laparoscopically via the abdominal approach. The two teams (transanal and transabdominal) meet near the peritoneal reflection.",[13],[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","robotic surgery vs transanal total mesorectal excsion","This study is designed to investigate the safety and superiority of transanal total mesorectal excision (taTME) in the treatment of rectal cancer compared with robot-assisted total mesorectal excision (rTME)",[9,15],null,[27],{"name":28,"affiliation":29,"role":30},"Liang Kang","Sixth Affiliated Hospital, Sun Yat-sen University","PRINCIPAL_INVESTIGATOR",[32,37],{"name":33,"role":34,"phone":35,"phoneExt":25,"email":36},"Liang Kang, MD","CONTACT","+8613602886833","kangl@mail.sysu.edu.cn",{"name":38,"role":34,"phone":39,"phoneExt":25,"email":36},"Ling Shuang Luo, MD","+8613751756175",[41],{"facility":42,"status":43,"city":44,"state":45,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":25},"the sixth affiliated hospital of Sun Yat-sen University","RECRUITING","Guangzhou","Guangdong","510655","China","CN",{"type":50,"coordinates":51},"Point",[52,53],113.25,23.11667,{"lat":53,"lon":52},{"type":30,"investigatorFullName":56,"investigatorTitle":57,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Yanhong Deng","Doctor","100642462","transanal-total-mesorectal-excision-vs-robotic-total-mesorectal-excision-100642462",false,"NCT07651553","Transanal Total Mesorectal Excision vs Robotic Total Mesorectal Excision","A Prospective, Randomized, Parallel-Controlled, Superiority Clinical Study Comparing Transanal Total Mesorectal Excision (taTME) and Robot-Assisted Total Mesorectal Excision (RTME) in the Treatment of Low Rectal Cancer","TaLaR03","Inclusion Criteria:Newly diagnosed patients aged 18-75 years. Pathologically confirmed adenocarcinoma (tubular, papillary, mucinous, or signet-ring). Tumor ≤7 cm from anal verge (MRI or DRE). Clinical stage T1-T3, N+, M0 (AJCC 8th ed.), suitable for sphincter-preserving TME. ASA score I-III.\n\nECOG performance status 0-1. Informed consent obtained.\n\n\\- Exclusion Criteria: Synchronous\u002Fmetachronous colorectal cancers, local recurrence, or distant metastases. Bowel obstruction, perforation, bleeding requiring emergency surgery. Involvement of sphincter or adjacent organs requiring Inter-sphincter Resection (ISR). Poor preoperative anal function\u002Fincontinence. IBD or familial adenomatous polyposis (FAP).\n\nPregnancy or lactation. Severe psychiatric illness. Other malignancies within 5 years. Severe comorbidities or infections making surgery intolerable. Judged unsuitable by investigator.","ALL","18 Years","75 Years",{"count":70,"type":71},216,"ESTIMATED","INTERVENTIONAL",[74],"NA","TME remains standard treatment for rectal cancer. Both Robotic TME and taTME are innovative surgical techniques with potential advantages in low rectal cancer. To date, no clinical studies have directly compared the conversion and complication rates between taTME and RTME in this population. Therefore, the investigators propose to conduct a prospective, randomized, parallel-controlled clinical trial comparing taTME with RTME for low rectal cancer, aiming to provide high-level evidence for surgical decision-making and benefit more patients.",[77,78],"Rectal Cancer Patients","Robotic Assisted Intervention",[9,15,80],"rectal cancer","2026-06-10",{"date":83,"type":84},"2026-06-16","ACTUAL",{"date":86,"type":84},"2025-06-30",{"date":88,"type":71},"2029-04-28",{"name":5,"class":6},1]