[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100598601":3},{"organization":4,"armGroups":7,"interventions":15,"overallOfficials":25,"centralContacts":29,"locations":35,"responsibleParty":52,"collaborators":10,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":59,"acronym":10,"eligibilityCriteria":60,"healthyVolunteers":57,"sex":61,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":10,"studyType":67,"phases":10,"briefSummary":68,"conditions":69,"keywords":72,"overallStatus":37,"whyStopped":10,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"Children's Hospital Los Angeles","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Cohort",null,"Single ventricle fontan.",[13,14],"Diagnostic Test: Cardiopulmonary Exercise Testing (CPET)","Diagnostic Test: Shear Wave Elastography Scan",[16,21],{"type":17,"name":18,"description":19,"armGroupLabels":20,"otherNames":10},"DIAGNOSTIC_TEST","Cardiopulmonary Exercise Testing (CPET)","CPET will be performed on a cycle ergometer using a ramp protocol designed to achieve an exercise time of 8-12 min. The entire procedure duration is approximately 60 min. CPET will be completed 6 months to 1 day before the cardiac catheterization and will be repeated 3-6 months following cardiac catheterization.",[9],{"type":17,"name":22,"description":23,"armGroupLabels":24,"otherNames":10},"Shear Wave Elastography Scan","The study lasts approximately 20 minutes. Shear Wave Elastography will be completed 6 months to 1 day before the cardiac catheterization. The Scan will be repeated 2-4 weeks following cardiac catheterization, and 3-6 months following cardiac catheterization.",[9],[26],{"name":27,"affiliation":5,"role":28},"Neil Patel, MD","PRINCIPAL_INVESTIGATOR",[30],{"name":31,"role":32,"phone":33,"phoneExt":10,"email":34},"Molly Moxness","CONTACT","3233619823","mmoxness@chla.usc.edu",[36],{"facility":5,"status":37,"city":38,"state":39,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"RECRUITING","Los Angeles","California","90027","United States","US",{"type":44,"coordinates":45},"Point",[46,47],-118.24368,34.05223,{"lat":47,"lon":46},[50,51],{"name":31,"role":32,"phone":33,"phoneExt":10,"email":34},{"name":27,"role":28,"phone":10,"phoneExt":10,"email":10},{"type":28,"investigatorFullName":53,"investigatorTitle":54,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Neil Patel","Medical Staff\u002FUSC Faculty CWR • Cardiology CWR","100598601","transcatheter-fontan-stenting-impact-on-hepatic-stiffness-and-exercise-capacity-100598601",false,"NCT07073612","Transcatheter Fontan Stenting: Impact on Hepatic Stiffness and Exercise Capacity","Inclusion Criteria:\n\n* Functionally single-ventricle Fontan-palliated patients undergoing clinically indicated cardiac catheterization\n* Anticipated Fontan stent placement for extracardiac Fontan conduit stenosis at the discretion of the primary operator\n* Weight ≥ 50 kg\n* 12-21 years of age\n\nExclusion Criteria:\n\n* Interrupted IVC\n* Greater than mild atrioventricular valve regurgitation on most recent echocardiogram or MRI (RF \\> 20%).\n* Greater than mild systemic ventricular dysfunction on most recent echo or MRI (EF \\\u003C 40%).\n* Non-sinus rhythm\n* Pacemaker\n* Inability to perform exercise test due to developmental or physical disability","ALL","12 Years","21 Years",{"count":65,"type":66},20,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to assess the clinical impact following Fontan stent placement for extracardiac Fontan conduit (EFC) stenosis in patients with single-ventricle Fontan-palliated patients ages 12-21 years old.\n\nThe main question it aims to:\n\n-Assess changes in exercise capacity by cardiopulmonary exercise testing and liver stiffness assessed by shear wave elastography before and after EFC stenting.\n\nParticipants will undergo two cardiopulmonary exercise tests and three shear wave elastography scans.",[70,71],"Single-ventricle","Stenosis",[73,74,70],"Stent","fontan","2025-07-10",{"date":77,"type":78},"2025-07-18","ACTUAL",{"date":80,"type":66},"2025-08-01",{"date":82,"type":66},"2027-12-01",{"name":5,"class":6},1]