[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100551459":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":33,"locations":39,"responsibleParty":55,"collaborators":25,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":63,"eligibilityCriteria":64,"healthyVolunteers":59,"sex":65,"minAge":66,"maxAge":25,"enrollmentInfo":67,"targetDuration":25,"studyType":70,"phases":71,"briefSummary":73,"conditions":74,"keywords":76,"overallStatus":41,"whyStopped":25,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"Kuopio University Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Transcranial alternating current stimulation (TACS)","EXPERIMENTAL","Experimental intervention is alternating sinusoidal current at frequency of 40 Hz applied for 60 min through a pair of saline-soaked surface sponge electrodes. One electrode is placed with the center over Pz position according to the 10-20 international EEG coordinates (an area overlying the medial parietal cortex and the precuneus) and the other over the right deltoid muscle.",[13],"Device: Transcranial alternating current stimulation (TACS)",{"label":15,"type":16,"description":17,"interventionNames":18},"Sham TACS","SHAM_COMPARATOR","The same electrodes are connected to the patient as in trial intervention. In sham treatment, a few seconds of actual current is provided and then the device automatically turns off. This is to ensure that patients cannot distinguish between real and sham treatments based on possible tingling of skin when starting the electrical current.",[19],"Device: Sham TACS",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"DEVICE","Transcranial alternating sinusoidal current at frequency of 40 Hz applied for 60 min through a pair of saline-soaked surface sponge electrodes.",[9],null,{"type":22,"name":15,"description":27,"armGroupLabels":28,"otherNames":25},"Sham treatment with few seconds of actual electrical current and same electrode configuration",[15],[30],{"name":31,"affiliation":5,"role":32},"Stepani Bendel","PRINCIPAL_INVESTIGATOR",[34],{"name":35,"role":36,"phone":37,"phoneExt":25,"email":38},"Ville Ihalainen","CONTACT","+358 447176388","ville.ihalainen@pshyvinvointialue.fi",[40],{"facility":5,"status":41,"city":42,"state":25,"zip":25,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"RECRUITING","Kuopio","Finland","FI",{"type":46,"coordinates":47},"Point",[48,49],27.67703,62.89238,{"lat":49,"lon":48},[52],{"name":53,"role":36,"phone":54,"phoneExt":25,"email":38},"Ville Ihalainen, MD","+358447176388",{"type":56,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100551459","transcranial-alternating-current-stimulation-on-patients-with-delirium-and-critical-illness-delitacs-100551459",false,"NCT06460363","Transcranial Alternating Current Stimulation on Patients with Delirium and Critical Illness (DeliTACS)","Transcranial Alternating Current Stimulation on Patients with Delirium and Critical Illness: a Randomized, Controlled, Double Blind, Proof-of-concept Pilot Study","DeliTACS","Inclusion Criteria:\n\n* Delirium in intensive care and duration of delirium for more than 24 hours. Delirium is defined as 4 or more points on ICDSC and -1 or more points on RASS.\n\nExclusion Criteria:\n\n* Under 18 years of age, pregnancy, delirium tremens, epilepsy or history of seizures any time before first trial intervention, active psychotic disease, infection of central nervous system, acute intoxication, traumatic brain injury, stroke, intracranial bleeding and implanted electronic devices.","ALL","18 Years",{"count":68,"type":69},78,"ESTIMATED","INTERVENTIONAL",[72],"NA","The goal of this clinical trial is to learn if transcranial alternating current stimulation can shorten the duration of delirium in intensive care setting. The main question it aims to answer:\n\n* Is it possible to shorten the duration of delirium with transcranial alternating current stimulation?\n\nResearchers will compare experimental treatment to sham.\n\nParticipants will receive experimental or sham treatment on maximum of two days depending on their delirium status. Duration of delirium is recorded and reported as \"days alive and free of delirium\".",[75],"Delirium",[75,77,78,79],"Tacs","Brain stimulation","Intensive care","2024-10-02",{"date":82,"type":83},"2024-10-04","ACTUAL",{"date":85,"type":83},"2024-09-06",{"date":87,"type":69},"2028-12-31",{"name":5,"class":6},1]