[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100573030":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":24,"locations":33,"responsibleParty":50,"collaborators":19,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":19,"eligibilityCriteria":59,"healthyVolunteers":55,"sex":60,"minAge":61,"maxAge":62,"enrollmentInfo":63,"targetDuration":19,"studyType":66,"phases":67,"briefSummary":69,"conditions":70,"keywords":74,"overallStatus":35,"whyStopped":19,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"University of Michigan","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"transcranial alternating current stimulation (tACS)","EXPERIMENTAL","Participants will receive 3 sessions of tACS. Each session can be active or sham. The stimulation parameters regarding the active and sham will not be disclosed at this time to maintain blind to participants. At the end of the trial the study will be updated to list these.",[13],"Device: transcranial alternating current stimulation (tACS)",[15],{"type":16,"name":9,"description":17,"armGroupLabels":18,"otherNames":19},"DEVICE","During each of the 3 stimulation visits, participants will be seated in a comfortable position and a cap will be placed on participant's head similar to a swimming cap. Small electrodes will be placed near the surface of the scalp at certain regions of interest, and a weak electrical current will be passed through the electrodes into speech related brain areas for 20 minutes. The study team will not use current strengths exceeding 2 milliamps (mA).",[9],null,[21],{"name":22,"affiliation":5,"role":23},"Soo-Eun Chang, PhD","PRINCIPAL_INVESTIGATOR",[25,29],{"name":22,"role":26,"phone":27,"phoneExt":19,"email":28},"CONTACT","734-232-0300","sooeunc@umich.edu",{"name":30,"role":26,"phone":31,"phoneExt":19,"email":32},"Emily Garnett, PhD","734-232-3371","emilyog@med.umich.edu",[34],{"facility":5,"status":35,"city":36,"state":37,"zip":38,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"RECRUITING","Ann Arbor","Michigan","48109","United States","US",{"type":42,"coordinates":43},"Point",[44,45],-83.74088,42.27756,{"lat":45,"lon":44},[48,49],{"name":22,"role":26,"phone":27,"phoneExt":19,"email":28},{"name":22,"role":23,"phone":19,"phoneExt":19,"email":19},{"type":23,"investigatorFullName":51,"investigatorTitle":52,"investigatorAffiliation":5,"oldNameTitle":19,"oldOrganization":19},"Soo-Eun Chang","Associate Professor of Psychiatry","100573030","transcranial-alternating-current-stimulation-tacs-in-stuttering-100573030",false,"NCT06740968","Transcranial Alternating Current Stimulation (tACS) in Stuttering","Improving Neural Oscillation and Synchrony Between Motor and Auditory Regions in Stuttering Using Personalized Transcranial Alternating Current Stimulation (tACS)","Inclusion Criteria for stutterers:\n\n* Have normal language, hearing, and cognition\n* Speak English as the primary language\n* Currently stutter\n* Score (per protocol) a certain value on the Stuttering Severity Instrument (SSI-4).\n* Have not received any treatment for stuttering within the past year\n\nExclusion Criteria for stutterers:\n\n* History of seizures\n* Major medical or neurological illness (e.g., stroke, serious head trauma, brain infection, Parkinson's disease, etc.)\n* History of closed head injury with loss of consciousness (e.g., concussion)\n* Metal or electronic implants such as cochlear implants and pacemakers anywhere in the body\n* Braids or other hair styling that prevents direct access to the scalp (if removal not possible)\n* Currently pregnant","ALL","18 Years","65 Years",{"count":64,"type":65},80,"ESTIMATED","INTERVENTIONAL",[68],"NA","The purpose of this study is to investigate how mild, noninvasive electrical brain stimulation affects speech relevant brain areas, which may in turn affect speech fluency and speaking-related brain activity in people that stutter. The long-term goal of this study is to test the therapeutic potential of transcranial alternating current stimulation (tACS) for the treatment of stuttering.\n\nThe study team hypothesizes that if stuttering involves impaired initiation of motor programs, delta-tuned tACS will strengthen communication between brain regions and decrease stuttering. Therefore, delta-tuned sensorimotor tACS will be paired with fluency-induced speech (choral reading), which is hypothesized to decrease stuttering via improved auditory motor integration.",[71,72,73],"Stuttering, Adult","Stuttering, Childhood","Stuttering, Developmental",[75,76,77,78,79,80],"tACS","Magnetic resonance imaging","Electroencephalogram","Auditory perturbation","Neural oscillations","Brain stimulation","2025-09-05",{"date":83,"type":84},"2025-09-12","ACTUAL",{"date":86,"type":84},"2025-08-05",{"date":88,"type":65},"2029-12",{"name":5,"class":6},1]