[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100385276":3},{"organization":4,"armGroups":7,"interventions":43,"overallOfficials":51,"centralContacts":55,"locations":63,"responsibleParty":82,"collaborators":59,"id":85,"slug":86,"hasResults":87,"nctId":88,"briefTitle":89,"officialTitle":89,"acronym":59,"eligibilityCriteria":90,"healthyVolunteers":91,"sex":92,"minAge":93,"maxAge":94,"enrollmentInfo":95,"targetDuration":59,"studyType":98,"phases":99,"briefSummary":101,"conditions":102,"keywords":104,"overallStatus":65,"whyStopped":59,"lastUpdateSubmitDate":106,"lastUpdatePostDateStruct":107,"startDateStruct":110,"completionDateStruct":112,"leadSponsor":114,"locationsCount":115},{"fullName":5,"class":6},"Massachusetts General Hospital","OTHER",[8,14,18,22,26,30,34,38],{"label":9,"type":10,"description":11,"interventionNames":12},"Traumatic Brain Injury","EXPERIMENTAL","This group consists of individuals diagnosed with traumatic brain injury. This group will undergo three sessions of tDCS: two active sessions and one sham session. The order of the sessions is randomized.",[13],"Device: Transcranial Direct Current Stimulation",{"label":15,"type":10,"description":16,"interventionNames":17},"Major Depressive Disorder","This group consists of individuals diagnosed with major depressive disorder. This group will undergo three sessions of tDCS: two active sessions and one sham session. The order of the sessions is randomized.",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Bipolar Disorder","This group consists of individuals diagnosed with bipolar disorder. This group will undergo three sessions of tDCS: two active sessions and one sham session. The order of the sessions is randomized.",[13],{"label":23,"type":10,"description":24,"interventionNames":25},"Schizophrenia","This group consists of individuals diagnosed with schizophrenia. This group will undergo three sessions of tDCS: two active sessions and one sham session. The order of the sessions is randomized.",[13],{"label":27,"type":10,"description":28,"interventionNames":29},"Attention Deficit Hyperactivity Disorder","This group consists of individuals diagnosed with attention deficit hyperactivity disorder. This group will undergo three sessions of tDCS: two active sessions and one sham session. The order of the sessions is randomized.",[13],{"label":31,"type":10,"description":32,"interventionNames":33},"Borderline Personality Disorder","This group consists of individuals diagnosed with borderline personality disorder. This group will undergo three sessions of tDCS: two active sessions and one sham session. The order of the sessions is randomized.",[13],{"label":35,"type":10,"description":36,"interventionNames":37},"Substance Use Disorder","This group consists of individuals diagnosed with substance use disorder. This group will undergo three sessions of tDCS: two active sessions and one sham session. The order of the sessions is randomized.",[13],{"label":39,"type":40,"description":41,"interventionNames":42},"Healthy Controls","ACTIVE_COMPARATOR","This group consists of individuals diagnosed with healthy controls. This group will undergo three sessions of tDCS: two active sessions and one sham session. The order of the sessions is randomized.",[13],[44],{"type":45,"name":46,"description":47,"armGroupLabels":48,"otherNames":49},"DEVICE","Transcranial Direct Current Stimulation","In tDCS, electrodes are applied on the scalp to transmit direct current at low current amplitudes.",[27,19,31,39,15,23,35,9],[50],"tDCS",[52],{"name":53,"affiliation":5,"role":54},"Joan Camprodon, MD, PhD, MPH","PRINCIPAL_INVESTIGATOR",[56,60],{"name":53,"role":57,"phone":58,"phoneExt":59,"email":59},"CONTACT","6177265348",null,{"name":61,"role":57,"phone":62,"phoneExt":59,"email":59},"Patricia Cirillo, MD, PhD","6177243217",[64],{"facility":5,"status":65,"city":66,"state":67,"zip":68,"country":69,"countryCode":70,"cosmosGeoPoint":71,"geoPoint":76,"contacts":77},"RECRUITING","Boston","Massachusetts","02129","United States","US",{"type":72,"coordinates":73},"Point",[74,75],-71.05977,42.35843,{"lat":75,"lon":74},[78],{"name":79,"role":57,"phone":80,"phoneExt":59,"email":81},"Blake Andreou, BS","6177248780","bandreou@mgh.harvard.edu",{"type":54,"investigatorFullName":83,"investigatorTitle":84,"investigatorAffiliation":5,"oldNameTitle":59,"oldOrganization":59},"Joan A Camprodon, MD MPH PhD","Chief of Division of Neuropsychiatry, Director of TMS Clinic, Director of Lab for Neuropsychiatry and Neuromodulation","100385276","transcranial-direct-current-stimulation-tdcs-neuromodulation-of-executive-function-across-neuropsychiatric-populations-100385276",false,"NCT04296604","Transcranial Direct Current Stimulation (tDCS) Neuromodulation of Executive Function Across Neuropsychiatric Populations","Inclusion Criteria\n\n1. Male and female outpatients 18-65 years of age\n2. A diagnosis of traumatic brain injury, major depressive disorder, bipolar disorder, schizophrenia, attention deficit hyperactivity disorder, borderline personality disorder and substance use disorders meeting the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) criteria.\n\nExclusion Criteria\n\n1. Contraindication to tDCS: history or epilepsy, metallic implants in the head and neck, brain stimulators, vagus nerve stimulators, shunts, pacemakers, pregnancy.\n2. Active substance dependence (except for tobacco and cannabis).\n3. Pregnant or nursing females.\n4. Inability to participate in testing procedures.\n5. Additional exclusion criteria for healthy controls:\n\n   1. Diagnosis of psychiatric of neurological disorder\n   2. Ongoing treatment with any psychotropic medications.",true,"ALL","18 Years","65 Years",{"count":96,"type":97},600,"ESTIMATED","INTERVENTIONAL",[100],"NA","In the current study, the investigators aim to understand the role of transcranial direct current stimulation (tDCS) in improving executive function across neuropsychiatric populations known to have deficits in this cognitive domain.",[9,15,19,23,27,31,103],"Substance Use Disorders",[46,105],"Executive Function","2025-09-04",{"date":108,"type":109},"2025-09-10","ACTUAL",{"date":111,"type":109},"2014-09",{"date":113,"type":97},"2026-04",{"name":5,"class":6},1]