[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100572804":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":32,"locations":38,"responsibleParty":64,"collaborators":66,"id":70,"slug":71,"hasResults":72,"nctId":73,"briefTitle":74,"officialTitle":74,"acronym":26,"eligibilityCriteria":75,"healthyVolunteers":72,"sex":76,"minAge":77,"maxAge":26,"enrollmentInfo":78,"targetDuration":26,"studyType":81,"phases":82,"briefSummary":84,"conditions":85,"keywords":26,"overallStatus":87,"whyStopped":26,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":97},{"fullName":5,"class":6},"Boston University Charles River Campus","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Active transcranial stimulation","EXPERIMENTAL","This group will receive active transcranial alternating current stimulation that matches the envelope of the target speech.",[13,14],"Device: Transcranial current stimulation","Behavioral: Auditory training",{"label":16,"type":17,"description":18,"interventionNames":19},"Sham stimulation","SHAM_COMPARATOR","This group will receive transcranial stimulation that ramps on and off before the speech is presented.",[14],[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Transcranial current stimulation","The transcranial alternating current stimulation is delivered during the speech stimulus and the current matches the envelope of the target speech",[9],null,{"type":28,"name":29,"description":30,"armGroupLabels":31,"otherNames":26},"BEHAVIORAL","Auditory training","An at-home auditory training program that adaptively and interactively trains the listener in degraded speech, cognitive skills, and communication strategies",[9,16],[33],{"name":34,"role":35,"phone":36,"phoneExt":26,"email":37},"Elin Roverud, AuD, PhD","CONTACT","617-358-7440","erover@bu.edu",[39],{"facility":40,"status":26,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Communication Neuroscience Research Lab at Boston University","Boston","Massachusetts","02215","United States","US",{"type":47,"coordinates":48},"Point",[49,50],-71.05977,42.35843,{"lat":50,"lon":49},[53,57,60,62],{"name":54,"role":35,"phone":55,"phoneExt":26,"email":56},"Tyler Perrachione, PhD","617-358-7410","tkp@bu.edu",{"name":58,"role":35,"phone":26,"phoneExt":26,"email":59},"Monique Montoute","mmontout@bu.edu",{"name":34,"role":61,"phone":26,"phoneExt":26,"email":26},"PRINCIPAL_INVESTIGATOR",{"name":54,"role":63,"phone":26,"phoneExt":26,"email":26},"SUB_INVESTIGATOR",{"type":65,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR",[67],{"name":68,"class":69},"National Institute on Deafness and Other Communication Disorders (NIDCD)","NIH","100572804","transcranial-stimulation-combined-with-auditory-training-100572804",false,"NCT06738030","Transcranial Stimulation Combined With Auditory Training","Inclusion Criteria:\n\n* 50 years of age or older\n* Audiometric thresholds that do not exceed 90 dB HL at any frequency from 250-6000 Hz\n* Able to provide informed consent and understand experimental instructions\n* Able to read print on a computer screen\n* Difficulty with speech-on-speech understanding\n* Access to computer or mobile phone with access to internet that can play sound (for the at-home training)\n\nExclusion Criteria:\n\n* Non-native speakers of English\n* History of skull fracture, scalp tissue damage, metallic implants around the head, seizures, neurological disorders, or traumatic brain injury, current or suspected pregnancy","ALL","50 Years",{"count":79,"type":80},94,"ESTIMATED","INTERVENTIONAL",[83],"NA","The goal of this clinical trial is to learn if non-invasive brain stimulation (called transcranial stimulation) can enhance the benefits from auditory training in people who struggle to understand one talker when many people are talking at the same time. The main questions it aims to answer are:\n\n* Does transcranial stimulation improve speech-on-speech understanding in people who struggle with this task?\n* Does transcranial stimulation enhance the benefits of a commercially available auditory training program?\n\nResearchers will compare transcranial stimulation to sham stimulation (no stimulation is applied during the listening task).\n\nParticipants will:\n\n* Receive login information to an online auditory training program to complete at home over 2 weeks\n* Visit the laboratory 4 times to receive transcranial stimulation while listening to speech-on-speech: once before at-home training, two times during the at-home training period, and once after at-home training has ended",[86],"Difficulties Understanding Speech in Noise","NOT_YET_RECRUITING","2024-12-12",{"date":90,"type":91},"2024-12-17","ACTUAL",{"date":93,"type":80},"2025-01-20",{"date":95,"type":80},"2026-08",{"name":5,"class":6},1]