[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100548444":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":25,"locations":31,"responsibleParty":51,"collaborators":24,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":60,"eligibilityCriteria":61,"healthyVolunteers":56,"sex":62,"minAge":63,"maxAge":24,"enrollmentInfo":64,"targetDuration":24,"studyType":67,"phases":68,"briefSummary":70,"conditions":71,"keywords":24,"overallStatus":34,"whyStopped":24,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":82},{"fullName":5,"class":6},"Beijing Tiantan Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"taVNS with \"standard-stimulation parameters\"","ACTIVE_COMPARATOR","with a current stimulation frequency of 25 Hz and a pulse width of 250 μs",[13],"Device: transauricular auricular vagus nerve stimulation",{"label":15,"type":16,"description":17,"interventionNames":18},"taVNS with \"low-stimulation parameters\"","SHAM_COMPARATOR","with a current stimulation frequency of 1 Hz and a pulse width of 250 μs.",[13],[20],{"type":21,"name":22,"description":22,"armGroupLabels":23,"otherNames":24},"DEVICE","transauricular auricular vagus nerve stimulation",[15,9],null,[26],{"name":27,"role":28,"phone":29,"phoneExt":24,"email":30},"Ruquan Han, MD","CONTACT","8610-59976660","ruquan.han@ccmu.edu.cn",[32],{"facility":33,"status":34,"city":35,"state":24,"zip":36,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"Beijing Tiantan Hospital, Capital Medical University","RECRUITING","Beijing","100070","China","CN",{"type":40,"coordinates":41},"Point",[42,43],116.39723,39.9075,{"lat":43,"lon":42},[46,49],{"name":47,"role":28,"phone":29,"phoneExt":24,"email":48},"Ruquan Han, M.D., Ph.D","ruquan.han@gmail.com",{"name":47,"role":50,"phone":24,"phoneExt":24,"email":24},"PRINCIPAL_INVESTIGATOR",{"type":50,"investigatorFullName":52,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"Ruquan Han","professor","100548444","transcutaneous-auricular-vagus-nerve-stimulation-prevents-postoperative-delirium-in-elderly-patients-100548444",false,"NCT06421077","Transcutaneous Auricular Vagus Nerve Stimulation Prevents Postoperative Delirium in Elderly Patients","Transcutaneous Auricular Vagus Nerve Stimulation （taVNS）Prevents Postoperative Delirium in Elderly Patients: a Randomized Controlled Study","Vnstar","Inclusion Criteria:\n\n* Age≥65 years\n* Expected operation time≥ 2 hours\n* Postoperative hospital stay≥ 4 days\n* Sign the informed consent form\n\nExclusion Criteria:\n\n* Neurosurgery or cardiac surgery\n* Emergency surgery within 6 hours of admission\n* End-stage disease with an expected survival of \\\u003C 3 months\n* Preoperative severe cognitive dysfunction affected perioperative cognitive function assessment\n* Severe sinus bradycardia, AVB of degree II and above, pacemaker placement","ALL","65 Years",{"count":65,"type":66},1776,"ESTIMATED","INTERVENTIONAL",[69],"NA","According to the 3D-CAM scale, evaluate the incidence of Postoperative Delirium within 5 days after surgery in elderly patients receiving taVNS.The results are expected to provide evidence of the safety and efficacy of perioperative prophylactic use of taVNS in the clinical application of improving postoperative brain health in elderly patients, as well as theoretical and practical basis for subsequent studies or clinical applications.",[72],"Vagus Nerve Stimulation","2025-04-21",{"date":75,"type":76},"2025-04-25","ACTUAL",{"date":78,"type":76},"2024-06-20",{"date":80,"type":66},"2025-12-31",{"name":5,"class":6},1]