[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100588811":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":11,"centralContacts":11,"locations":11,"responsibleParty":28,"collaborators":11,"id":32,"slug":33,"hasResults":34,"nctId":35,"briefTitle":36,"officialTitle":37,"acronym":11,"eligibilityCriteria":38,"healthyVolunteers":34,"sex":39,"minAge":40,"maxAge":41,"enrollmentInfo":42,"targetDuration":11,"studyType":45,"phases":46,"briefSummary":48,"conditions":49,"keywords":51,"overallStatus":55,"whyStopped":11,"lastUpdateSubmitDate":56,"lastUpdatePostDateStruct":57,"startDateStruct":60,"completionDateStruct":62,"leadSponsor":64,"locationsCount":11},{"fullName":5,"class":6},"Karadeniz Technical University","OTHER",[8,14,17,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Group 1: Patients with low EF who receive TEDS","EXPERIMENTAL",null,[13],"Device: Transcutaneous Diaphragm Stimulation",{"label":15,"type":10,"description":11,"interventionNames":16},"Group 2: Patients with high EF who receive TEDS",[13],{"label":18,"type":19,"description":11,"interventionNames":11},"Group 3: Patients with low EF who do not receive TEDS","NO_INTERVENTION",{"label":21,"type":19,"description":11,"interventionNames":11},"Group 4: Patients with high EF who do not receive TEDS",[23],{"type":24,"name":25,"description":26,"armGroupLabels":27,"otherNames":11},"DEVICE","Transcutaneous Diaphragm Stimulation","In the ICU, TEDS is administered by a physiotherapist once daily for 20 minutes, five days a week, as part of the routine treatment protocol. The stimulation is delivered using the LGT-231 model device from the LONGEST brand.\n\nA transcutaneous current with a frequency of 30-50 Hz and a pulse width of 300-400 microseconds is applied to the diaphragm. The stimulation intensity is increased until visible muscle contraction is achieved.",[9,15],{"type":29,"investigatorFullName":30,"investigatorTitle":31,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","A. Oguzhan KUCUK","MD","100588811","transcutaneous-diaphragm-stimulation-in-icu-patients-100588811",false,"NCT06946251","Transcutaneous Diaphragm Stimulation in ICU Patients","Evaluation of Patients With Reduced and Preserved Ejection Fraction After Transcutaneous Diaphragm Stimulation","Inclusion Criteria:\n\n* Patients aged between 18 and 80 years\n* Patients expected to require mechanical ventilation for at least 72 hours\n\nExclusion Criteria:\n\n* Presence of known neuromuscular diseases that contraindicate the use of transcutaneous diaphragm stimulation\n* Phrenic nerve injury\n* History of abdominal or thoracic surgery that prevents the application of diaphragm stimulation","ALL","18 Years","80 Years",{"count":43,"type":44},76,"ESTIMATED","INTERVENTIONAL",[47],"NA","The aim of this study is to compare the effects of transcutaneous electrical diaphragm stimulation (TEDS) on diaphragm thickness, duration of mechanical ventilation, length of ICU stay, and right\u002Fleft heart functions between patient groups with low and high ejection fraction (EF) levels.\n\nThis randomized controlled trial will record demographic data, diaphragm ultrasound measurements, and echocardiographic findings of patients who receive or do not receive TEDS for five consecutive days.\n\nParticipants will be divided into four groups according to their EF levels and whether or not they receive diaphragm stimulation:\n\nGroup 1: Patients with low EF who receive TEDS Group 2: Patients with high EF who receive TEDS Group 3: Patients with low EF who do not receive TEDS Group 4: Patients with high EF who do not receive TEDS\n\nDiaphragm thickness and echocardiographic assessments will be performed at baseline and at the end of the five-day TEDS intervention.\n\nTEDS Application Protocol\n\nIn the ICU, TEDS is administered by a physiotherapist once daily for 20 minutes, five days a week, as part of the routine treatment protocol. The stimulation is delivered using the LGT-231 model device from the LONGEST brand.\n\nA transcutaneous current with a frequency of 30-50 Hz and a pulse width of 300-400 microseconds is applied to the diaphragm. The stimulation intensity is increased until visible muscle contraction is achieved.\n\nElectrode placement involves:\n\nThe first pair of electrodes placed bilaterally between the 8th and 10th anterior intercostal spaces, lateral to the xiphoid process.\n\nThe second pair placed along the mid-axillary line of the thorax, also between the 8th and 10th intercostal spaces.",[50],"Intensive Care Patients",[52,53,54],"Diaphragm Stimulation","Intensive care unit","Ejection Fraction","NOT_YET_RECRUITING","2025-04-18",{"date":58,"type":59},"2025-04-27","ACTUAL",{"date":61,"type":44},"2025-05",{"date":63,"type":44},"2026-05",{"name":5,"class":6}]