[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100450958":3},{"organization":4,"armGroups":7,"interventions":23,"overallOfficials":33,"centralContacts":38,"locations":48,"responsibleParty":65,"collaborators":67,"id":71,"slug":72,"hasResults":73,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":29,"eligibilityCriteria":77,"healthyVolunteers":73,"sex":78,"minAge":79,"maxAge":80,"enrollmentInfo":81,"targetDuration":29,"studyType":84,"phases":85,"briefSummary":87,"conditions":88,"keywords":90,"overallStatus":51,"whyStopped":29,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":103},{"fullName":5,"class":6},"Göteborg University","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"TENS (transcutaneous electrical nerve stimulation)","ACTIVE_COMPARATOR","Patients with endometriosis-related chronic frequent pain and high pain intensity (≥ 4 according to Numeric Rating Scale, NRS) randomized to transcutaneous electrical nerve stimulation as add-on treatment in addition to conventional analgesic treatment. Treatment with transcutaneous electrical nerve stimulation (TENS) during 16 weeks.",[13],"Device: Transcutaneous electrical nerve stimulation (TENS)",{"label":15,"type":10,"description":16,"interventionNames":17},"Conventional analgesic treatment","Patients with endometriosis related chronic frequent pain and high pain intensity (≥ 4 according to Numeric Rating Scale, NRS) randomized to conventional analgesic treatment for 8 weeks. After 8 weeks the patients are treated with transcutaneous electrical nerve stimulation (TENS) during 16 weeks.",[18],"Other: Conventional analgesic treatment",{"label":20,"type":10,"description":21,"interventionNames":22},"External control group","Patients with endometriosis-related pain that is not frequent or without high pain intensity (\\\u003C 4 according to Numeric Rating Scale, NRS) constitute an external control group. The patients are treated with transcutaneous electrical nerve stimulation as add-on treatment in addition to conventional analgesic treatment. Treatment with transcutaneous electrical nerve stimulation (TENS) during 16 weeks.",[13],[24,30],{"type":25,"name":26,"description":27,"armGroupLabels":28,"otherNames":29},"DEVICE","Transcutaneous electrical nerve stimulation (TENS)","Treatment with transcutaneous electrical nerve stimulation (TENS) during 16 weeks.",[20,9],null,{"type":6,"name":15,"description":31,"armGroupLabels":32,"otherNames":29},"Conventional analgesic treatment. Conventional analgesic treatment may include no pharmacological treatment if the patient does not use any analgesics.",[15],[34],{"name":35,"affiliation":36,"role":37},"Paulin Andéll, MD","Göteborgs Universitet\u002FVästra Götalands Regionen","PRINCIPAL_INVESTIGATOR",[39,44],{"name":40,"role":41,"phone":42,"phoneExt":29,"email":43},"Paulin Andréll, MD, PhD","CONTACT","+46-31-3438259","paulin.andrell@gu.se",{"name":45,"role":41,"phone":46,"phoneExt":29,"email":47},"Cecilia Ögren, RN","+46-31-3425000","cecilia.ogren@vgregion.se",[49],{"facility":50,"status":51,"city":52,"state":29,"zip":29,"country":53,"countryCode":54,"cosmosGeoPoint":55,"geoPoint":60,"contacts":61},"Pain Centre, Department of Anaesthesiology and Intensive Care Medicine Östra, Sahlgrenska University Hospital, Region Västra Götaland","RECRUITING","Gothenburg","Sweden","SE",{"type":56,"coordinates":57},"Point",[58,59],11.96679,57.70716,{"lat":59,"lon":58},[62,63],{"name":40,"role":41,"phone":29,"phoneExt":29,"email":29},{"name":64,"role":41,"phone":29,"phoneExt":29,"email":29},"Josefin Larsson, RN",{"type":66,"investigatorFullName":29,"investigatorTitle":29,"investigatorAffiliation":29,"oldNameTitle":29,"oldOrganization":29},"SPONSOR",[68],{"name":69,"class":70},"Vastra Gotaland Region","OTHER_GOV","100450958","transcutaneous-electrical-nerve-stimulation-for-endometriosis-related-chronic-pain-100450958",false,"NCT05152264","Transcutaneous Electrical Nerve Stimulation for Endometriosis-related Chronic Pain","High Frequency, High Intensity Transcutaneous Electrical Nerve Stimulation for Endometriosis-related Chronic Pain - a Randomized Controlled Trial","Inclusion Criteria:\n\n* Age ≥18 years\n* Consents to participation in the study\n* Verified endometriosis (by laparoscopy or ultrasound).\n* Chronic endometriosis-related pain (\\> 3 months), available for TENS treatment\n* Functioning, stable endometriosis-specific hormonal drug therapy. The endometriosis-specific drug therapy must be unchanged for the last 3 months and no gynecological surgical procedures for the treatment of endometriosis are planned during the next 7 months (during study participation). The endometriosis-specific drug therapy does not refer to analgesic therapy for symptom relief of endometriosis-related pain.\n\nExclusion Criteria:\n\n* Patient with inability to understand and use written and spoken Swedish\n* Patient with pacemaker and\u002For ICD or other electronic implants\n* Patient with impaired sensation over the painful area\n* Malignant disease with an expected survival \\\u003C12 months\n* Alcohol or substance abuse\n* Serious untreated psychiatric illness and\u002For psychological condition that is the primary determinant of the patient's condition\n* Participating in another intervention study with possible impact on current study outcome measures\n* Patient who is using \\>90 morphine equivalents\u002Fday\n* Patient who is electro-acupuncture\n* Pregnancy","FEMALE","18 Years","100 Years",{"count":82,"type":83},40,"ESTIMATED","INTERVENTIONAL",[86],"NA","The study evaluates the effect of TENS (transcutaneous electrical nerve stimulation) as add-on treatment compared with conventional analgesic treatment in patients with endometriosis-related chronic pain. Patients with frequent pain and high pain intensity will be randomized to additional treatment with TENS or conventional treatment for 8 weeks to evaluate the acute effects of TENS treatment (n=40). Patients with endometriosis-related pain that is not frequent or without high pain intensity constitute an external control group. All patients in the study will receive TENS treatment for a total of 16 weeks, for evaluation of long-term effects of TENS treatment.",[89],"Endometriosis-related Pain",[91,92,93],"Endometriosis","Chronic pain","Transcutaneous electrical nerve stimulation","2025-05-20",{"date":96,"type":97},"2025-05-23","ACTUAL",{"date":99,"type":97},"2021-11-12",{"date":101,"type":83},"2028-12",{"name":5,"class":6},1]