[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100589144":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":34,"locations":40,"responsibleParty":54,"collaborators":25,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":25,"eligibilityCriteria":64,"healthyVolunteers":60,"sex":65,"minAge":66,"maxAge":25,"enrollmentInfo":67,"targetDuration":25,"studyType":70,"phases":71,"briefSummary":73,"conditions":74,"keywords":76,"overallStatus":42,"whyStopped":25,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"Shirley Ryan AbilityLab","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Experimental Group","ACTIVE_COMPARATOR","This group receives task specific training and transcutaneous spinal cord stimulation (TESS) during treatment sessions. TESS is applied via electrodes placed vertically over the spinous processes of C5-C6. The stimulation will be adjusted within a range of 10mA to 100mA based on participant tolerance and will be delivered for 30 minutes per training session.",[13,14],"Other: Task Specific Training (TST)","Other: Transcutaneous electrical spinal cord stimulation (TESS)",{"label":16,"type":10,"description":17,"interventionNames":18},"Comparator Group","This group receives task specific training without real TESS during treatment sessions. Instead, they receive Sham TESS, which is a placebo version in which the electrodes are applied and the stimulation is turned on so that the patient can feel it, and then ramped down to zero for the duration of the session.",[13,19],"Other: Sham transcutaneous electrical spinal cord stimulation (Sham TESS)",[21,26,30],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"Task Specific Training (TST)","Task specific training activities are types of activities that may be used in standard of care for stroke rehabilitation. Tasks will be completed in sitting or standing. As is usual in studies for upper limb hemiparesis, study participants will be picking up objects with their affected hands. They will work on grasp, grasp-lift of objects, release of objects, reaching and grasping, and reaching without grasping.",[16,9],null,{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Transcutaneous electrical spinal cord stimulation (TESS)","The Digitimer DS8R Transcutaneous Spinal Cord Neurostimulator will deliver transcutaneous electrical spinal cord stimulation. The stimulus intensity used during the intervention will be determined based on individual maximum tolerance. We expect this current amplitude to be between 10mA and 100mA. Stimulation time will be standardized to a 30min duration during which the participant will perform task specific training tasks.",[9],{"type":6,"name":31,"description":32,"armGroupLabels":33,"otherNames":25},"Sham transcutaneous electrical spinal cord stimulation (Sham TESS)","The Sham TESS intervention will utilize the same device and setup as the true TESS intervention. However, after turning on the stimulation and reaching the appropriate intensity, the stimulation will be ramped down and turned off for the remainder of the treatment session. The participant will be told that the stimulation was brought down to a sub-threshold level in order to maintain treatment group blinding.",[16],[35],{"name":36,"role":37,"phone":38,"phoneExt":25,"email":39},"Mary Ellen Stoykov, PhD, OT","CONTACT","773-704-2422","mstoykov@sralab.org",[41],{"facility":5,"status":42,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":25},"RECRUITING","Chicago","Illinois","60611","United States","US",{"type":49,"coordinates":50},"Point",[51,52],-87.65005,41.85003,{"lat":52,"lon":51},{"type":55,"investigatorFullName":56,"investigatorTitle":57,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Mary Ellen Stoykov","Research Scientist, Principal Investigator","100589144","transcutaneous-electrical-stimulation-for-stroke-patients-100589144",false,"NCT06950593","Transcutaneous Electrical Stimulation for Stroke Patients","Upper Limb Function Following Transcutaneous Electrical Spinal Cord Stimulation in Individuals With Hemiplegic Stroke","Inclusion Criteria:\n\n* 18 years or older\n* able and willing to give written consent and comply with study procedures\n* at least 6 months post-stroke\n* hemiplegia secondary to stroke\n* UE Fugle Meyer Assessment \\\u003C35\n* not currently receiving regular occupational therapy services\n* participant has received clearance from physician to participate in study\n* participant has at least a rudimentary comprehension of English\n\nExclusion Criteria:\n\n* botox injection in upper extremity within the last 4 months\n* modified ashworth score of 4 in any joint of the affected limb\n* pregnant or nursing\n* using a powered, implanted cardiac device for monitoring or support of heart function (i.e. pacemaker, defibrillator, or LVAD), or anti-spasticity implantable pumps, or cochlear implants\n* unhealed bone fractures\n* severe contractures in the upper extremities\n* active cancer or cancer remission less than 5 years\n* orthopedic dysfunction, injury, or surgery that would impact the individual's ability to use the upper extremities\n* recent procedure or operation of the spinal cord within the past year\n* traumatic brain injury or neurological conditions that would impact the study\n* skull fracture that has developed within the past 6 months\n* non-English speakers","ALL","18 Years",{"count":68,"type":69},14,"ESTIMATED","INTERVENTIONAL",[72],"NA","This study aims to evaluate the feasibility and impact of transcutaneous electrical stimulation of the spinal cord (TESS) on the recovery of post-stroke individuals who have upper limb hemiparesis. It will compare outcomes measures between individuals who receive upper limb task specific training with TESS and individuals who receive task specific training of the upper limb with Sham, or fake, TESS.",[75],"Upper Limb Hemiparesis Following Stroke",[77,78,79],"upper limb hemiparesis","stroke","transcutaneous spinal cord stimulation (TESS)","2025-08-07",{"date":82,"type":83},"2025-08-12","ACTUAL",{"date":85,"type":69},"2025-08-18",{"date":87,"type":69},"2027-01-01",{"name":5,"class":6},1]