[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100586649":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":25,"centralContacts":31,"locations":37,"responsibleParty":57,"collaborators":24,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":24,"eligibilityCriteria":66,"healthyVolunteers":62,"sex":67,"minAge":68,"maxAge":69,"enrollmentInfo":70,"targetDuration":24,"studyType":73,"phases":74,"briefSummary":76,"conditions":77,"keywords":24,"overallStatus":40,"whyStopped":24,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"Mayo Clinic","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Functional motor training with transcutaneous spinal cord stimulation","EXPERIMENTAL","Transcutaneous spinal cord stimulation will be delivered to the skin over the lower thoracic and lumbar spine region using adhesive electrodes for ages 5-11 for one multi-hour visit. The effects of stimulation will be recorded via electrophysiological and biomechanical metrics described within the outcomes measures.",[13],"Device: Transcutaneous stimulation",{"label":15,"type":10,"description":16,"interventionNames":17},"Extended functional motor training with transcutaneous spinal cord stimulation","An extended functional training arm for a subset of 10 subjects, ages 12-18, in which they will receive up to twelve multi-hour sessions of a therapeutic neuromuscular strengthening intervention within a 6 week period.",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"DEVICE","Transcutaneous stimulation","DS8R (Digitimer LLC) for transcutaneous neurostimulation.",[15,9],null,[26,29],{"name":27,"affiliation":5,"role":28},"Kristin Zhao, Ph.D.","PRINCIPAL_INVESTIGATOR",{"name":30,"affiliation":5,"role":28},"Joline Brandenburg, M.D.",[32],{"name":33,"role":34,"phone":35,"phoneExt":24,"email":36},"Julie Block","CONTACT","507-255-7393","Block.Julie@mayo.edu",[38],{"facility":39,"status":40,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Mayo Clinic in Rochester","RECRUITING","Rochester","Minnesota","55905","United States","US",{"type":47,"coordinates":48},"Point",[49,50],-92.4699,44.02163,{"lat":50,"lon":49},[53],{"name":54,"role":34,"phone":55,"phoneExt":24,"email":56},"Kristin D Zhao, Ph.D","507-284-8942","Zhao.Kristin@mayo.edu",{"type":28,"investigatorFullName":58,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"Kristin Zhao, PhD","Principal Investigator","100586649","transcutaneous-spinal-stimulation-for-children-and-youth-with-spina-bifida-100586649",false,"NCT06918119","Transcutaneous Spinal Stimulation for Children and Youth With Spina Bifida","Characterization of Transcutaneous Spinal Cord Stimulation for Enabling Reflex Motor Evoked Responses in Children and Youth With Spina Bifida","Inclusion Criteria\n\n* Congenital diagnosis of myelomeningocele (MMC)\n* Able to follow verbal commands or instructions.\n* If female and able to become pregnant, must be willing to use medically-acceptable method of contraception during study participation.\n\nExclusion Criteria\n\n* Severe cognitive deficits demonstrating inability to communicate needs\n* Gaping, weeping, or unhealed open wounds at the site of electrode placement\n* Unhealed fractures on load bearing bones\n* History of osteoporosis\n* History of implanted electronic devices at the stimulation location(e.g. deep brain stimulator, cardiac pacemaker, diaphragmatic pacer, baclofen pumps, insulin pumps, etc.)\n* Pregnancy\n* Epilepsy\n* History of seizure\n* Ongoing infections (currently being treated or are symptomatic)\n* Any illness or condition which, based on the research team's assessment, will compromise the patient's ability to comply with the protocol, patient safety, or the validity of the data collected during this study.","ALL","5 Years","18 Years",{"count":71,"type":72},30,"ESTIMATED","INTERVENTIONAL",[75],"NA","A study to use transcutaneous spinal cord stimulation to characterize sensorimotor deficits in a pediatric population of individuals with spina bifida.",[78,79],"Myelomeningocele","Spina Bifida","2025-10-09",{"date":82,"type":83},"2025-10-14","ACTUAL",{"date":85,"type":83},"2025-08-07",{"date":87,"type":72},"2030-07",{"name":5,"class":6},1]