[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100629098":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":32,"centralContacts":38,"locations":44,"responsibleParty":62,"collaborators":26,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":68,"acronym":26,"eligibilityCriteria":69,"healthyVolunteers":70,"sex":71,"minAge":72,"maxAge":73,"enrollmentInfo":74,"targetDuration":26,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":83,"overallStatus":85,"whyStopped":26,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"University of Florida","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Active tVNS","EXPERIMENTAL","Participants receive active transcutaneous vagus nerve stimulation (tVNS). Participants also complete either an evaluative stress task or a non-evaluative control task as part of the factorial design.",[13,14],"Device: Transcutaneous Vagus Nerve Stimulation (tVNS)","Behavioral: Evaluative Stress Task",{"label":16,"type":17,"description":18,"interventionNames":19},"Sham Comparator","SHAM_COMPARATOR","Participants receive sham transcutaneous vagus nerve stimulation. Participants also complete either an evaluative stress task or a non-evaluative control task as part of the factorial design.",[13,14],[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Transcutaneous Vagus Nerve Stimulation (tVNS)","Transcutaneous vagus nerve stimulation delivered via an auricular stimulation device. Participants receive either active stimulation or sham stimulation depending on random assignment",[9,16],null,{"type":28,"name":29,"description":30,"armGroupLabels":31,"otherNames":26},"BEHAVIORAL","Evaluative Stress Task","Participants complete either an evaluative stress-induction task involving social evaluation or a non-evaluative control task. Task condition is assigned as part of the factorial design.",[9,16],[33,36],{"name":34,"affiliation":5,"role":35},"Trevor Foulk, Organizational Behavior","STUDY_DIRECTOR",{"name":37,"affiliation":5,"role":35},"Dustin Hegland, MD-ANESTHESIOLOGY-GENERAL",[39],{"name":40,"role":41,"phone":42,"phoneExt":26,"email":43},"Pedepo Emmanuel, Organizational Behavior","CONTACT","813-834-7991","pedepo.emmanuel@warrington.ufl.edu",[45],{"facility":5,"status":26,"city":46,"state":47,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"Gainesville","Florida","32611","United States","US",{"type":52,"coordinates":53},"Point",[54,55],-82.32483,29.65163,{"lat":55,"lon":54},[58],{"name":59,"role":41,"phone":60,"phoneExt":26,"email":61},"Trevor Foulk, PhD in Management","301-807-0397","Trevor.foulk@warrington.ufl.edu",{"type":63,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100629098","transcutaneous-vagus-nerve-stimulation-tvns-and-stress-regulation-during-performance-tasks-100629098",false,"NCT07470229","Transcutaneous Vagus Nerve Stimulation (tVNS) and Stress Regulation During Performance Tasks","Inclusion Criteria:\n\n\\- Adults aged 18 to 65 years\n\nFluent in English\n\nAble to provide informed consent\n\nAble to complete study procedures during a single laboratory session\n\nExclusion Criteria:\n\n\\- History of neurological or psychiatric disorders\n\nCardiovascular disease or uncontrolled hypertension\n\nImplanted electrical devices (e.g., pacemaker)\n\nCurrent pregnancy\n\nContraindications to transcutaneous vagus nerve stimulation (tVNS)\n\nCurrent use of medications that significantly affect autonomic nervous system functioning",true,"ALL","18 Years","65 Years",{"count":75,"type":76},200,"ESTIMATED","INTERVENTIONAL",[79],"NA","This study examines how individuals respond to performance-related tasks and whether a non-invasive ear stimulation device influences stress responses during those tasks. Participants will be randomly assigned to use either an active or inactive (placebo) version of a transcutaneous vagus nerve stimulation (tVNS) device during a laboratory session.\n\nThe study includes two task conditions. In one condition, participants will prepare a brief speech under evaluative conditions designed to induce stress. In the other condition, participants will complete a non-evaluative writing task. During the session, participants will wear a heart rate monitor and complete short questionnaires assessing their current feelings, including state anxiety.\n\nThe primary objective is to determine whether active tVNS is associated with lower state anxiety during a performance-related stress task compared to placebo stimulation. Secondary outcomes include heart rate and task-related responses. The study will also examine whether individual differences in stress reactivity influence responses to stimulation.\n\nParticipation involves one laboratory session lasting approximately 45 minutes.",[82],"Stress Response",[84],"transcutaneous vagus nerve stimulation tVNS, stress regulation state anxiety , Trier Social Stress Test, performance","NOT_YET_RECRUITING","2026-03-10",{"date":88,"type":89},"2026-03-13","ACTUAL",{"date":91,"type":76},"2026-03-15",{"date":93,"type":76},"2026-04-15",{"name":5,"class":6},1]