[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100595727":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":18,"centralContacts":23,"locations":31,"responsibleParty":69,"collaborators":71,"id":73,"slug":74,"hasResults":75,"nctId":76,"briefTitle":77,"officialTitle":77,"acronym":78,"eligibilityCriteria":79,"healthyVolunteers":80,"sex":81,"minAge":82,"maxAge":83,"enrollmentInfo":84,"targetDuration":10,"studyType":87,"phases":10,"briefSummary":88,"conditions":89,"keywords":96,"overallStatus":100,"whyStopped":10,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":109,"locationsCount":110},{"fullName":5,"class":6},"Tampere University Hospital","OTHER",[8,12,15],{"label":9,"type":10,"description":11,"interventionNames":10},"Patients with HPV associated disease",null,"1\\) colposcopy clinic detected persisting HR-HPV infection, 2) diagnosed cervical cancer; or 3) diagnosed Oral squamous cell carcinoma (OSCC).",{"label":13,"type":10,"description":14,"interventionNames":10},"Offspring of patients with HPV associated disease","Children over 12 years old",{"label":16,"type":10,"description":17,"interventionNames":10},"Sexual partner (spouse) of patients with HPV associated disease","Women or men",[19],{"name":20,"affiliation":21,"role":22},"Karolina Louvanto, Professor","Tampere University","PRINCIPAL_INVESTIGATOR",[24,28],{"name":20,"role":25,"phone":26,"phoneExt":10,"email":27},"CONTACT","+35850 4713838","karolina.louvanto@pirha.fi",{"name":29,"role":25,"phone":10,"phoneExt":10,"email":30},"Eerika Karinen, Licentiate of Medicine","eerika.karinen@tuni.fi",[32,55],{"facility":33,"status":10,"city":34,"state":10,"zip":10,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"Kuopio University Hospital","Kuopio","Finland","FI",{"type":38,"coordinates":39},"Point",[40,41],27.67703,62.89238,{"lat":41,"lon":40},[44,48,51,53],{"name":45,"role":25,"phone":46,"phoneExt":10,"email":47},"Anna Jouppila-Mättö, Doctor of medical science","+35844 7172834","anna.jouppila-matto@pshyvinvointialue.fi",{"name":49,"role":25,"phone":10,"phoneExt":10,"email":50},"Teemu Taalamo, Licentiate of Medicine","teemu.taalamo@pshyvinvointialue.fi",{"name":45,"role":52,"phone":10,"phoneExt":10,"email":10},"SUB_INVESTIGATOR",{"name":54,"role":52,"phone":10,"phoneExt":10,"email":10},"Teemu Taalamo, Licentiate of medicine",{"facility":5,"status":10,"city":56,"state":10,"zip":10,"country":35,"countryCode":36,"cosmosGeoPoint":57,"geoPoint":61,"contacts":62},"Tampere",{"type":38,"coordinates":58},[59,60],23.78712,61.49911,{"lat":60,"lon":59},[63,64,65,66,68],{"name":20,"role":25,"phone":26,"phoneExt":10,"email":27},{"name":29,"role":25,"phone":10,"phoneExt":10,"email":30},{"name":20,"role":22,"phone":10,"phoneExt":10,"email":10},{"name":67,"role":52,"phone":10,"phoneExt":10,"email":10},"Ilkka Kivekäs, Professor",{"name":29,"role":52,"phone":10,"phoneExt":10,"email":10},{"type":70,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[72],{"name":33,"class":6},"100595727","transmission-of-oncogenic-hpv-infection-among-families-100595727",false,"NCT07036211","Transmission of Oncogenic HPV Infection Among Families","TREVINO","Inclusion Criteria:\n\n* Patient with colposcopy clinic detected persisting HR-HPV infection\n* Patient with diagnosed cervical cancer\n* Patient with diagnosed OSCC\n* Patients' sexual partners of women or men that are referred to the colposcopy\u002Fgynecological oncology\u002FENT\n* offspring (over 12 years old) of the referred couples\n\nExclusion Criteria:\n\n* Candidate who don't speak Finnish",true,"ALL","12 Years","100 Years",{"count":85,"type":86},700,"ESTIMATED","OBSERVATIONAL","The goal of the Transmission of Oncogenic HPV Infection Among Families (TREVINO) study is to improve understanding of how high-risk human papillomavirus (HPV) infections are transmitted within families. The research focuses on transmission between sexual partners and between parents and children. It also examines how the various microbes may influence the persistence of HPV infections and the development of HPV-related cancers.\n\nThe study will include up to 300 couples recruited from gynecology and ear, nose, and throat (ENT) clinics in Finland, as well as their children. Participants include individuals with persistent HPV infection, cervical precancer or cancer, or HPV-related head and neck cancer, along with their partners and potentially their offspring.\n\nParticipants will provide self-collected samples from the oral and genital areas at multiple time points over up to five years. Questionnaires addressing medical, behavioural, and environmental factors will be completed.\n\nThe study is conducted at Tampere University Hospital and Kuopio University Hospital in Finland. Results will inform HPV screening and prevention programs, improve understanding of family-level transmission, and identify potential microbial and genetic markers linked to cancer risk.",[90,91,92,93,94,95],"Human Papilloma Virus (HPV)","Cervical Carcinoma","Oropharyngeal Carcinoma","Transmission Vertical","Transmission","Human Papillomavirus Infection",[97,98,99],"Oropharyngeal cancer","Cervical cancer","HPV","NOT_YET_RECRUITING","2025-06-16",{"date":103,"type":104},"2025-06-25","ACTUAL",{"date":106,"type":86},"2025-08",{"date":108,"type":86},"2031-12",{"name":5,"class":6},2]