[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100593998":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":17,"centralContacts":17,"locations":17,"responsibleParty":23,"collaborators":17,"id":27,"slug":28,"hasResults":29,"nctId":30,"briefTitle":31,"officialTitle":32,"acronym":17,"eligibilityCriteria":33,"healthyVolunteers":29,"sex":34,"minAge":35,"maxAge":17,"enrollmentInfo":36,"targetDuration":17,"studyType":39,"phases":40,"briefSummary":42,"conditions":43,"keywords":47,"overallStatus":49,"whyStopped":17,"lastUpdateSubmitDate":50,"lastUpdatePostDateStruct":51,"startDateStruct":54,"completionDateStruct":55,"leadSponsor":57,"locationsCount":17},{"fullName":5,"class":6},"Chinese PLA General Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"transversus abdominis plane block group","EXPERIMENTAL","The procedure was performed by anesthesiologists with extensive expertise in nerve blockade techniques. For upper abdominal surgical incisions, a subcostal approach transversus abdominis plane block (TAPB) was implemented under ultrasound guidance to identify the transversus abdominis plane. A total of 20 mL of 0.33% ropivacaine hydrochloride injection (Naropin®) was incrementally administered, followed by contralateral application using identical techniques, with ultrasonographic confirmation of fusiform drug distribution within the transversus abdominis plane to achieve upper abdominal incision analgesia. For lower abdominal incisions, a lateral approach was employed, with the same dosage of local anesthetic injected at the target site and bilateral blocks performed after confirming fluid dispersion patterns under real-time ultrasound visualization.",[13],"Procedure: Transversus Abdominis Plane Block, TAPB",{"label":15,"type":16,"description":17,"interventionNames":17},"Non-intervention Control Group","NO_INTERVENTION",null,[19],{"type":20,"name":21,"description":11,"armGroupLabels":22,"otherNames":17},"PROCEDURE","Transversus Abdominis Plane Block, TAPB",[9],{"type":24,"investigatorFullName":25,"investigatorTitle":26,"investigatorAffiliation":5,"oldNameTitle":17,"oldOrganization":17},"PRINCIPAL_INVESTIGATOR","Weidong Mi","Director, Department of Anesthesiology (Cheif expert of National key research and development program of China 2018YFC2001900)","100593998","transversus-abdominis-plane-block-on-postoperative-analgesic-efficacy-in-elderly-patients-undergoing-minimally-invasive-gastrointestinal-tumor-surgery-100593998",false,"NCT07013721","Transversus Abdominis Plane Block on Postoperative Analgesic Efficacy in Elderly Patients Undergoing Minimally Invasive Gastrointestinal Tumor Surgery","A Clinical Study on the Effect of Ultrasound-Guided Transversus Abdominis Plane Block on Postoperative Analgesic Efficacy in Elderly Patients Undergoing Minimally Invasive Gastrointestinal Tumor Surgery","Inclusion Criteria:\n\n1. Elderly patients scheduled for elective minimally invasive gastrointestinal tumor surgery under general anesthesia\n2. Age ≥65 years\n3. American Society of Anesthesiologists (ASA) physical status classification ≤III\n4. Body mass index (BMI) 18-30 kg\u002Fm²\n\nExclusion Criteria:\n\n1. Allergy to anesthetic agents\n2. Preoperative chronic pain or chronic use of opioids\u002Fnonsteroidal anti-inflammatory drugs (NSAIDs)\n3. Contraindications to regional blockade:Local infection at puncture site\n\n   , Coagulopathy (INR \\>1.5, platelet count \\\u003C80×10⁹\u002FL)\n4. There is cognitive impairment, which is determined based on Mini Mental State Examination (MMSE) scores below the standard threshold\n5. Preoperative neurological\u002Fpsychiatric disorders:Consciousness alterations, Epilepsy, Alzheimer's disease, Parkinson's disease, Schizophrenia, Anxiety or depressive disorders, Hepatic, pulmonary, or renal encephalopathy\n6. Recent stroke history\n7. Postoperative admission to intensive care unit (ICU)","ALL","65 Years",{"count":37,"type":38},102,"ESTIMATED","INTERVENTIONAL",[41],"NA","Elderly patients undergoing minimally invasive gastrointestinal tumor surgery face complex postoperative pain management due to age-related physiological decline and surgical particularities, where traditional opioids are prone to adverse effects. Our study investigates the clinical analgesic efficacy of ultrasound-guided transversus abdominis plane block (TAPB) in these patients, focusing on analgesic quality, delirium incidence, opioid consumption, and postoperative recovery indicators. This evaluation aims to assess its clinical value and safety while providing evidence-based insights for optimizing perioperative analgesia protocols.",[44,45,46],"Regional Anaesthesia","Transversus Abdominis Plane Block (TAP Block)","Pain, Postoperative",[44,48,46],"Transversus abdominis plane block (TAP block)","NOT_YET_RECRUITING","2025-06-02",{"date":52,"type":53},"2025-06-10","ACTUAL",{"date":50,"type":38},{"date":56,"type":38},"2026-04-15",{"name":5,"class":6}]