[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100558100":3},{"organization":4,"armGroups":7,"interventions":23,"overallOfficials":29,"centralContacts":33,"locations":39,"responsibleParty":52,"collaborators":12,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":12,"eligibilityCriteria":62,"healthyVolunteers":58,"sex":63,"minAge":64,"maxAge":12,"enrollmentInfo":65,"targetDuration":12,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":12,"overallStatus":75,"whyStopped":12,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"Saint-Joseph University","OTHER",[8,13,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Placebo","NO_INTERVENTION","This group receives standard analgesic treatment and no Transversus Thoracic Plane Block is performed",null,{"label":14,"type":15,"description":16,"interventionNames":17},"Transversus Thoracic Plane Block pre","ACTIVE_COMPARATOR","This group receives standard analgesic treatment and Transversus Thoracic Plane Block is performed before surgery",[18],"Procedure: Transversus Thoracic Plane Block",{"label":20,"type":15,"description":21,"interventionNames":22},"Transversus Thoracic Plane Block post","This group receives standard analgesic treatment and Transversus Thoracic Plane Block is performed at the end of surgery",[18],[24],{"type":25,"name":26,"description":27,"armGroupLabels":28,"otherNames":12},"PROCEDURE","Transversus Thoracic Plane Block","The Transversus Thoracic Plane Block is a recent regional anesthesia technique. It provides analgesia for the anterior cutaneous branches of the intercostal nerves T2-6 to the medial anterior chest wall via a single injection of local anesthesia between the internal intercostal muscle and the transversus thoracic muscle located between the third and fourth (or fourth and fifth) intercostal space. It is noteworthy that the TTPB can consequently reduce pulmonary morbidity and the need for high-dose opioids.",[20,14],[30],{"name":31,"affiliation":5,"role":32},"Samia Madi Jebara, MD,PHD","STUDY_DIRECTOR",[34],{"name":35,"role":36,"phone":37,"phoneExt":12,"email":38},"Joanna Tohme, MD","CONTACT","+96170492735","joanna-tohme@hotmail.com",[40],{"facility":41,"status":12,"city":42,"state":12,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":12},"Hotel Dieu de France","Beirut","166830","Lebanon","LB",{"type":47,"coordinates":48},"Point",[49,50],35.50157,33.89332,{"lat":50,"lon":49},{"type":53,"investigatorFullName":54,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":12,"oldOrganization":12},"PRINCIPAL_INVESTIGATOR","Joanna Tohme","Medical Doctor, Principal investigator","100558100","transversus-thoracic-plane-block-for-perioperative-analgesia-in-cardiac-surgery-100558100",false,"NCT06546722","Transversus Thoracic Plane Block for Perioperative Analgesia in Cardiac Surgery","Transversus Thoracic Plane Block for Perioperative Analgesia in Cardiac Surgery: a Randomized Controlled Prospective Study","Inclusion Criteria:\n\n\\- All patients scheduled for cardiac surgery via sternotomy under cardiopulmonary bypass\n\nExclusion Criteria:\n\n* Previous cardiac surgery\n* Urgent surgery\n* Pregnant women\n* Allergy to local anesthetics\n* Opioid dependence\n* Low ejection fraction \\\u003C 30%\n* Presence or onset of cognitive or neurological disorders preventing pain assessment\n* Infection at injection sites\n* Coagulopathy\n* Patients on dual antiplatelet therapy\n* Renal insufficiency with Glomerular filtration rate (GFR) \\\u003C 30 mL\u002Fmin\n* History of thoracic radiotherapy\n* History of mastectomy","ALL","18 Years",{"count":66,"type":67},150,"ESTIMATED","INTERVENTIONAL",[70],"NA","The goal of this clinical trial is to learn if perioperative Transversus Thoracic Plane Block (TTPB) decrease perioperative pain after cardiac surgery. The main questions it aims to answer are:\n\n1. does Transversus Thoracic Plane Block decrease perioperative pain after cardiac surgery more than the standard analgesic treatment?\n2. Are the results different if the investigators perform Transversus Thoracic Plane Block before surgery or at the end of surgery?",[26,73,74],"Cardiac Surgery","Post Operative Pain","NOT_YET_RECRUITING","2024-08-07",{"date":78,"type":79},"2024-08-09","ACTUAL",{"date":81,"type":67},"2024-09-01",{"date":83,"type":67},"2025-12-30",{"name":5,"class":6},1]